81 FR 7820 - Center for Scientific Review; Notice of Closed Meetings

DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health

Federal Register Volume 81, Issue 30 (February 16, 2016)

Page Range		7820-7820
FR Document		2016-02974

Federal Register, Volume 81 Issue 30 (Tuesday, February 16, 2016)

[Federal Register Volume 81, Number 30 (Tuesday, February 16, 2016)]
[Notices]
[Page 7820]
From the Federal Register Online  [www.thefederalregister.org]
[FR Doc No: 2016-02974]



[[Page 7820]]

-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Center for Scientific Review; Notice of Closed Meetings

    Pursuant to section 10(d) of the Federal Advisory Committee Act, as 
amended (5 U.S.C. App.), notice is hereby given of the following 
meetings.
    The meetings will be closed to the public in accordance with the 
provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 
U.S.C., as amended. The grant applications and the discussions could 
disclose confidential trade secrets or commercial property such as 
patentable material, and personal information concerning individuals 
associated with the grant applications, the disclosure of which would 
constitute a clearly unwarranted invasion of personal privacy.

    Name of Committee: AIDS and Related Research Integrated Review 
Group, AIDS Discovery and Development of Therapeutics Study Section.
    Date: March 8, 2016.
    Time: 8:00 a.m. to 6:00 p.m.
    Agenda: To review and evaluate grant applications.
    Place: Residence Inn Bethesda, 7335 Wisconsin Avenue, Bethesda, 
MD 20814.
    Contact Person: Shiv A Prasad, Ph.D., Scientific Review Officer, 
Center for Scientific Review, National Institutes of Health, 6701 
Rockledge Drive, Room 5220, MSC 7852, Bethesda, MD 20892, 301-443-
5779, [email protected].

    Name of Committee: Center for Scientific Review Special Emphasis 
Panel, Infectious Diseases and Microbiology.
    Date: March 8, 2016.
    Time: 9:30 a.m. to 6:00 p.m.
    Agenda: To review and evaluate grant applications.
    Place: National Institutes of Health, 6701 Rockledge Drive, 
Bethesda, MD 20892 (Virtual Meeting).
    Contact Person: Guangyong Ji, Ph.D., Scientific Review Officer, 
Center for Scientific Review, National Institutes of Health, 6701 
Rockledge Drive, Room 3211, MSC 7808, Bethesda, MD 20892, 301-435-
1146, [email protected].

    Name of Committee: Center for Scientific Review Special Emphasis 
Panel, AREA application in Infectious Diseases and Microbiology.
    Date: March 8, 2016.
    Time: 9:30 a.m. to 6:00 p.m.
    Agenda: To review and evaluate grant applications.
    Place: National Institutes of Health, 6701 Rockledge Drive, 
Bethesda, MD 20892, (Virtual Meeting).
    Contact Person: Liangbiao Zheng, Ph.D., Scientific Review 
Officer, Center for Scientific Review, National Institutes of 
Health, 6701 Rockledge Drive, Room 3202, MSC 7808, Bethesda, MD 
20892, 301-996-5819, [email protected].

(Catalogue of Federal Domestic Assistance Program Nos. 93.306, 
Comparative Medicine; 93.333, Clinical Research, 93.306, 93.333, 
93.337, 93.393-93.396, 93.837-93.844, 93.846-93.878, 93.892, 93.893, 
National Institutes of Health, HHS)

    Dated: February 9, 2016.
Sylvia Neal,
Program Analyst, Office of Federal Advisory Committee Policy.
[FR Doc. 2016-02974 Filed 2-12-16; 8:45 am]
 BILLING CODE 4140-01-P

7820 Federal Register / Vol. 81, No. 30 / Tuesday, February 16, 2016 / Notices

DEPARTMENT OF HEALTH AND (Catalogue of Federal Domestic Assistance Description of Technology
HUMAN SERVICES Program Nos. 93.306, Comparative Medicine;
93.333, Clinical Research, 93.306, 93.333, The only currently available treatment
National Institutes of Health 93.337, 93.393–93.396, 93.837–93.844, for Menkes disease, subcutaneous
93.846–93.878, 93.892, 93.893, National copper histidinate injections, is
Center for Scientific Review; Notice of Institutes of Health, HHS) successful only in patients with ATP7A
Closed Meetings Dated: February 9, 2016. gene mutations that do not completely
Sylvia Neal, corrupt ATP7A copper transport
Pursuant to section 10(d) of the function (estimated 20–25% of affected
Federal Advisory Committee Act, as Program Analyst, Office of Federal Advisory
Committee Policy. patients) and when started at a very
amended (5 U.S.C. App.), notice is early age (first month of life). The
hereby given of the following meetings. [FR Doc. 2016–02974 Filed 2–12–16; 8:45 am]
combination of viral gene therapy with
The meetings will be closed to the BILLING CODE 4140–01–P
copper injections provides working
public in accordance with the copies of the ATP7A copper transporter
provisions set forth in sections into the brain, together with a source of
552b(c)(4) and 552b(c)(6), Title 5 U.S.C., DEPARTMENT OF HEALTH AND
HUMAN SERVICES the substrate (copper) needed for proper
as amended. The grant applications and brain growth and clinical
the discussions could disclose neurodevelopment.
National Institutes of Health
confidential trade secrets or commercial Codon-optimized nucleic acids
property such as patentable material, Government-Owned Inventions; encoding a reduced-size ATP7A protein
and personal information concerning Availability for Licensing and compositions of AAV vectors were
individuals associated with the grant discovered by NICHD researchers along
applications, the disclosure of which AGENCY: National Institutes of Health, with methods of administering this
would constitute a clearly unwarranted HHS. therapy. Human P-type ATPase copper-
invasion of personal privacy. transporting ATPase 1 (ATP7A)
ACTION: Notice.
Name of Committee: AIDS and Related transports copper from enterocytes
Research Integrated Review Group, AIDS (where it is taken up from dietary
Discovery and Development of Therapeutics
SUMMARY: The invention listed below is
owned by an agency of the U.S. copper) into the blood. ATP7A also
Study Section.
Date: March 8, 2016. Government and is available for mediates passage of copper across the
Time: 8:00 a.m. to 6:00 p.m. licensing and/or co-development in the blood-cerebrospinal fluid (CSF) barrier
Agenda: To review and evaluate grant U.S. in accordance with 35 U.S.C. 209 and the blood-brain barrier. In Menkes
applications. and 37 CFR part 404 to achieve disease and occipital horn syndrome
Place: Residence Inn Bethesda, 7335 expeditious commercialization of (OHS), copper accumulates in intestinal
Wisconsin Avenue, Bethesda, MD 20814. cells and less copper is absorbed into
results of federally-funded research and
Contact Person: Shiv A Prasad, Ph.D., the blood, resulting in restricted copper
Scientific Review Officer, Center for development. Foreign patent
applications are filed on selected supply to other tissues, particularly the
Scientific Review, National Institutes of
Health, 6701 Rockledge Drive, Room 5220, inventions to extend market coverage brain. Death in infancy or early
MSC 7852, Bethesda, MD 20892, 301–443– for companies and may also be available childhood is a common consequence.
5779, prasads@csr.nih.gov. for licensing and/or co-development. Therapeutic delivery of the copper
Name of Committee: Center for Scientific transport protein via an AAV vector,
Review Special Emphasis Panel, Infectious ADDRESSES: Invention Development and combined with subcutaneous copper
Diseases and Microbiology. Marketing Unit, Technology Transfer histidinate treatment will relieve the
Date: March 8, 2016. Center, National Cancer Institute, 9609 copper deficiency to the brain and
Time: 9:30 a.m. to 6:00 p.m. Medical Center Drive, Mail Stop 9702, permit normal neurological
Agenda: To review and evaluate grant Rockville, MD 20850–9702. development and function.
applications.
Place: National Institutes of Health, 6701 FOR FURTHER INFORMATION CONTACT: Potential Commercial Applications
Rockledge Drive, Bethesda, MD 20892 Information on licensing and co-
(Virtual Meeting). development research collaborations, • Treatment of Menkes Disease,
Contact Person: Guangyong Ji, Ph.D., and copies of the U.S. patent Occipital Horn Syndrome, and of
Scientific Review Officer, Center for applications listed below may be ATP7A-related distal motor neuropathy
Scientific Review, National Institutes of obtained by contacting: Attn. Invention
Health, 6701 Rockledge Drive, Room 3211, Value Proposition
MSC 7808, Bethesda, MD 20892, 301–435– Development and Marketing Unit,
Technology Transfer Center, National • Provides working copies of the
1146, jig@csr.nih.gov.
Cancer Institute, 9609 Medical Center ATP7A copper transporter into the
Name of Committee: Center for Scientific brain, together with a source of the
Review Special Emphasis Panel, AREA Drive, Mail Stop 9702, Rockville, MD,
application in Infectious Diseases and 20850–9702, Tel. 240–276–5515 or substrate (copper) needed for proper
Microbiology. email ncitechtransfer@mail.nih.gov. A brain growth and clinical
Date: March 8, 2016. signed Confidential Disclosure neurodevelopment.
Time: 9:30 a.m. to 6:00 p.m. Agreement may be required to receive
Agenda: To review and evaluate grant
Development Stage
copies of the patent applications.
applications. Pre-clinical (in vivo validation)
SUPPLEMENTARY INFORMATION:
mstockstill on DSK4VPTVN1PROD with NOTICES

Place: National Institutes of Health, 6701
Rockledge Drive, Bethesda, MD 20892, Technology description follows. Inventor(s)
(Virtual Meeting). Stephen G. Kaler, M.D. (NICHD)
Contact Person: Liangbiao Zheng, Ph.D., Title of Invention
Scientific Review Officer, Center for Intellectual Property
Scientific Review, National Institutes of AAV-based Vectors for the
Health, 6701 Rockledge Drive, Room 3202, Therapeutic Management of Menkes HHS Reference No. E–062–2015/0
MSC 7808, Bethesda, MD 20892, 301–996– Disease and Related Copper Transport U.S. Provisional Application No. 62/
5819, zhengli@csr.nih.gov. Disorders 244,594 filed 21 October 2015

VerDate Sep<11>2014 22:15 Feb 12, 2016 Jkt 238001 PO 00000 Frm 00079 Fmt 4703 Sfmt 4703 E:\FR\FM\16FEN1.SGM 16FEN1

Document Created: 2016-02-13 03:13:41
Document Modified: 2016-02-13 03:13:41

Category		Regulatory Information
Collection		Federal Register
sudoc Class		AE 2.7: GS 4.107: AE 2.106:
Publisher		Office of the Federal Register, National Archives and Records Administration
Section		Notices
Dates		March 8, 2016.
FR Citation		81 FR 7820

81 FR 7820 - Center for Scientific Review; Notice of Closed Meetings

DEPARTMENT OF HEALTH AND HUMAN SERVICESNational Institutes of Health

Federal Register Volume 81, Issue 30 (February 16, 2016)

DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health