82_FR_21325 82 FR 21239 - Request for the Technical Review of 4 Draft Immediately Dangerous to Life or Health (IDLH) Value Profile Documents

82 FR 21239 - Request for the Technical Review of 4 Draft Immediately Dangerous to Life or Health (IDLH) Value Profile Documents

DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Prevention

Federal Register Volume 82, Issue 86 (May 5, 2017)

Page Range21239-21240
FR Document2017-09149

The National Institute for Occupational Safety and Health of the Centers for Disease Control and Prevention announces four (4) draft Immediately Dangerous to Life or Health (IDLH) Value Profile documents now available for public comment.

Federal Register, Volume 82 Issue 86 (Friday, May 5, 2017) 
[Federal Register Volume 82, Number 86 (Friday, May 5, 2017)]
[Notices]
[Pages 21239-21240]
From the Federal Register Online  [www.thefederalregister.org]
[FR Doc No: 2017-09149]


-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention

[Docket Number CDC-2017-0048, NIOSH 156-C]


Request for the Technical Review of 4 Draft Immediately Dangerous 
to Life or Health (IDLH) Value Profile Documents

AGENCY: National Institute for Occupational Safety and Health (NIOSH) 
of the Centers for Disease Control and Prevention (CDC), Department of 
Health and Human Services (HHS).

ACTION: Request for information and comments.

-----------------------------------------------------------------------

SUMMARY: The National Institute for Occupational Safety and Health of 
the Centers for Disease Control and Prevention announces four (4) draft 
Immediately Dangerous to Life or Health (IDLH) Value Profile documents 
now available for public comment.

Table of Contents

Dates
Addresses
For Further Information Contact
Supplementary Information
Background
Reference

DATES: Electronic or written comments must be received by June 19, 
2017.

ADDRESSES: You may submit responses, identified by CDC-2017-0048 and 
docket number NIOSH 156-C, by any of the following methods:
     Federal eRulemaking Portal: http://www.regulations.gov. 
Follow the instructions for submitting comments.
     Mail: National Institute for Occupational Safety and 
Health, NIOSH Docket Office, 1090 Tusculum Avenue, MS C-34, Cincinnati, 
Ohio 45226-1998.
    Instructions: All information received in response to this notice 
must include the agency name and docket number [CDC-2017-0048; NIOSH 
156-C]. All relevant responses received will be posted without change 
to www.regulations.gov, including any personal information provided. 
For access to the docket to read background documents or information 
received, go to www.regulations.gov. All information received in 
response to this notice will also be available for public examination 
and copying at the NIOSH Docket Office, 1150 Tusculum Avenue, Room 155, 
Cincinnati, OH 45226-1998.

FOR FURTHER INFORMATION CONTACT: G. Scott Dotson, NIOSH, Education and 
Information Division, 1090 Tusculum Avenue, C-32, Cincinnati, OH 45226, 
telephone (513) 533-8540 (not a toll free number).

SUPPLEMENTARY INFORMATION: NIOSH seeks comments on four (4) draft IDLH 
values and IDLH Value Profile documents. The draft IDLH Value Profile 
documents were developed to provide the scientific rationale behind 
derivation of IDLH values for the following chemicals:

----------------------------------------------------------------------------------------------------------------
               Document #                             Chemical                               CAS
----------------------------------------------------------------------------------------------------------------
B-01....................................  Acetonitrile....................  (# 75-05-8)
B-02....................................  Chloroacetonitrile..............  (# 107-14-2)
B-03....................................  Methacrylonitrile...............  (# 126-98-7)
B-04....................................  Nitrogen dioxide................  (# 10102-44-0)
----------------------------------------------------------------------------------------------------------------

    Each IDLH Value Profile document provides a detailed summary of the 
health hazards of acute exposures to high airborne concentrations and 
the rationale for the proposed IDLH value with the chemical(s) of 
interest.
    To facilitate the review of these documents, NIOSH requests that 
the following questions be taken into consideration:

    1. Does this document clearly outline the health hazards associated 
with acute (or short-term) exposures to the chemical? If not, what 
specific information is missing from the document?
    2. Are the rationale and logic behind the derivation of an IDLH 
value for a specific chemical clearly explained? If not, what specific 
information is needed to clarify the basis of the IDLH value?
    3. Are the conclusions supported by the data?
    4. Are the tables clear and appropriate?
    5. Is the document organized appropriately? If not, what 
improvements are needed?
    6. Are you aware of any scientific data reported in governmental 
publications, databases, peer-reviewed journals, or other sources that 
should be included within this document?

    Background: In 2013, NIOSH published Current Intelligence Bulletin 
(CIB) 66--Derivation of Immediately Dangerous to Life or Health (IDLH) 
Values [NIOSH 2013]. Since the establishment of the IDLH values in the 
1970s, NIOSH has continued to review available scientific data to 
improve the protocol used to derive acute exposure guidelines, in 
addition to the chemical-specific IDLH values. The information 
presented in this CIB represents the most recent update of the 
scientific rationale and the methodology (hereby referred to as the 
IDLH methodology) used to derive IDLH values. The primary objectives of 
this document are to:

1. Provide a brief history of the development of IDLH values
2. Update the scientific bases and risk assessment methodology used to 
derive IDLH values from quality data

[[Page 21240]]

3. Provide transparency behind the rationale and derivation process for 
IDLH values
4. Demonstrate how scientifically credible IDLH values can be derived 
from available data resources

    The IDLH methodology is based on a weight-of-evidence approach that 
applies scientific judgment for critical evaluation of the quality and 
consistency of scientific data and in extrapolation from the available 
data to the IDLH value. The weight-of-evidence approach refers to 
critical examination of all available data from diverse lines of 
evidence and the derivation of a scientific interpretation on the basis 
of the collective body of data, including its relevance, quality, and 
reported results. Conceptually, the derivation process for IDLH values 
is similar to that used in other risk-assessment applications, 
including these steps:

1. Hazard characterization
2. Identification of critical adverse effects
3. Identification of a point of departure (POD)
4. Application of appropriate uncertainty factors (UFs), based on the 
study and POD
5. Determination of the final risk value

Reference

NIOSH [2013]. Current intelligence bulletin 66: derivation of 
immediately dangerous to life or health (IDLH) values. Cincinnati, 
OH: US Department of Health and Human Services, Centers for Disease 
Control and Prevention, National Institute for Occupational Safety 
and Health, DHHS (NIOSH) Publication 2014-100.

John Howard,
Director, National Institute for Occupational Safety and Health, 
Centers for Disease Control and Prevention.
[FR Doc. 2017-09149 Filed 5-4-17; 8:45 am]
 BILLING CODE 4163-19-P

Federal Register / Vol. 82, No. 86 / Friday, May 5, 2017 / Notices 21239 Campus through the front entrance on DEPARTMENT OF HEALTH AND docket number NIOSH 156–C, by any of Clifton Road. Vehicles may be searched, HUMAN SERVICES the following methods: and the guard force will then direct • Federal eRulemaking Portal: http:// visitors to the designated parking area. Centers for Disease Control and www.regulations.gov. Follow the Upon arrival at the facility, visitors must Prevention instructions for submitting comments. present government-issued photo [Docket Number CDC–2017–0048, NIOSH • Mail: National Institute for identification (e.g., a valid federal 156–C] Occupational Safety and Health, NIOSH identification badge, state driver’s Docket Office, 1090 Tusculum Avenue, license, state non-driver’s identification Request for the Technical Review of 4 MS C–34, Cincinnati, Ohio 45226–1998. card, or passport). Non-United States Draft Immediately Dangerous to Life or Instructions: All information received citizens must complete the required Health (IDLH) Value Profile Documents in response to this notice must include security paperwork prior to the meeting the agency name and docket number AGENCY: National Institute for date and must present a valid passport, [CDC–2017–0048; NIOSH 156–C]. All Occupational Safety and Health relevant responses received will be visa, Permanent Resident Card, or other (NIOSH) of the Centers for Disease posted without change to type of work authorization document Control and Prevention (CDC), www.regulations.gov, including any upon arrival at the facility. All persons Department of Health and Human personal information provided. For entering the building must pass through Services (HHS). access to the docket to read background a metal detector. CDC Security ACTION: Request for information and documents or information received, go personnel will issue a visitor’s ID badge comments. to www.regulations.gov. All information at the entrance to Building 19. Visitors received in response to this notice will may receive an escort to the meeting SUMMARY: The National Institute for Occupational Safety and Health of the also be available for public examination room. All items brought to HHS/CDC and copying at the NIOSH Docket are subject to inspection. Centers for Disease Control and Prevention announces four (4) draft Office, 1150 Tusculum Avenue, Room Dated: May 2, 2017. Immediately Dangerous to Life or Health 155, Cincinnati, OH 45226–1998. Sandra Cashman, (IDLH) Value Profile documents now FOR FURTHER INFORMATION CONTACT: G. Executive Secretary, Centers for Disease available for public comment. Scott Dotson, NIOSH, Education and Control and Prevention. Information Division, 1090 Tusculum Table of Contents Avenue, C–32, Cincinnati, OH 45226, [FR Doc. 2017–09133 Filed 5–4–17; 8:45 am] Dates telephone (513) 533–8540 (not a toll free BILLING CODE 4163–18–P Addresses number). For Further Information Contact SUPPLEMENTARY INFORMATION: NIOSH Supplementary Information seeks comments on four (4) draft IDLH Background values and IDLH Value Profile Reference documents. The draft IDLH Value DATES: Electronic or written comments Profile documents were developed to must be received by June 19, 2017. provide the scientific rationale behind ADDRESSES: You may submit responses, derivation of IDLH values for the identified by CDC–2017–0048 and following chemicals: Document # Chemical CAS B–01 ....................................................... Acetonitrile ............................................................................................................ (# 75–05–8) B–02 ....................................................... Chloroacetonitrile .................................................................................................. (# 107–14–2) B–03 ....................................................... Methacrylonitrile .................................................................................................... (# 126–98–7) B–04 ....................................................... Nitrogen dioxide .................................................................................................... (# 10102–44–0) Each IDLH Value Profile document not, what specific information is needed 1970s, NIOSH has continued to review provides a detailed summary of the to clarify the basis of the IDLH value? available scientific data to improve the health hazards of acute exposures to 3. Are the conclusions supported by protocol used to derive acute exposure high airborne concentrations and the the data? guidelines, in addition to the chemical- rationale for the proposed IDLH value 4. Are the tables clear and specific IDLH values. The information with the chemical(s) of interest. appropriate? presented in this CIB represents the To facilitate the review of these 5. Is the document organized most recent update of the scientific documents, NIOSH requests that the appropriately? If not, what rationale and the methodology (hereby following questions be taken into improvements are needed? referred to as the IDLH methodology) consideration: 6. Are you aware of any scientific data used to derive IDLH values. The reported in governmental publications, primary objectives of this document are 1. Does this document clearly outline databases, peer-reviewed journals, or SRADOVICH on DSK3GMQ082PROD with NOTICES the health hazards associated with acute to: other sources that should be included (or short-term) exposures to the within this document? 1. Provide a brief history of the chemical? If not, what specific Background: In 2013, NIOSH development of IDLH values information is missing from the published Current Intelligence Bulletin 2. Update the scientific bases and risk document? (CIB) 66—Derivation of Immediately assessment methodology used to 2. Are the rationale and logic behind Dangerous to Life or Health (IDLH) derive IDLH values from quality the derivation of an IDLH value for a Values [NIOSH 2013]. Since the data specific chemical clearly explained? If establishment of the IDLH values in the VerDate Sep<11>2014 17:43 May 04, 2017 Jkt 241001 PO 00000 Frm 00054 Fmt 4703 Sfmt 4703 E:\FR\FM\05MYN1.SGM 05MYN1

21240 Federal Register / Vol. 82, No. 86 / Friday, May 5, 2017 / Notices 3. Provide transparency behind the an opportunity for the public to FOR FURTHER INFORMATION CONTACT: rationale and derivation process for comment on CMS’ intention to collect Reports Clearance Office at (410) 786– IDLH values information from the public. Under the 1326. 4. Demonstrate how scientifically Paperwork Reduction Act of 1995 (the SUPPLEMENTARY INFORMATION: credible IDLH values can be derived PRA), federal agencies are required to from available data resources publish notice in the Federal Register Contents The IDLH methodology is based on a concerning each proposed collection of This notice sets out a summary of the weight-of-evidence approach that information (including each proposed use and burden associated with the applies scientific judgment for critical extension or reinstatement of an existing following information collections. More evaluation of the quality and collection of information) and to allow detailed information can be found in consistency of scientific data and in 60 days for public comment on the each collection’s supporting statement extrapolation from the available data to proposed action. Interested persons are and associated materials (see the IDLH value. The weight-of-evidence invited to send comments regarding our ADDRESSES). approach refers to critical examination burden estimates or any other aspect of CMS–10320 Health Care Reform of all available data from diverse lines this collection of information, including Insurance Web Portal Requirements of evidence and the derivation of a the necessity and utility of the proposed 45 CFR part 159 scientific interpretation on the basis of information collection for the proper CMS–724 Medicare/Medicaid the collective body of data, including its performance of the agency’s functions, Psychiatric Hospital Survey Data and relevance, quality, and reported results. the accuracy of the estimated burden, Supporting Regulations Conceptually, the derivation process for ways to enhance the quality, utility, and Under the PRA (44 U.S.C. 3501– IDLH values is similar to that used in clarity of the information to be 3520), federal agencies must obtain other risk-assessment applications, collected, and the use of automated approval from the Office of Management including these steps: collection techniques or other forms of and Budget (OMB) for each collection of 1. Hazard characterization information technology to minimize the information they conduct or sponsor. 2. Identification of critical adverse information collection burden. The term ‘‘collection of information’’ is effects DATES: Comments must be received by defined in 44 U.S.C. 3502(3) and 5 CFR 3. Identification of a point of departure July 5, 2017. 1320.3(c) and includes agency requests (POD) or requirements that members of the 4. Application of appropriate ADDRESSES: When commenting, please public submit reports, keep records, or uncertainty factors (UFs), based on reference the document identifier or provide information to a third party. the study and POD OMB control number. To be assured Section 3506(c)(2)(A) of the PRA 5. Determination of the final risk value consideration, comments and requires federal agencies to publish a recommendations must be submitted in Reference 60-day notice in the Federal Register any one of the following ways: concerning each proposed collection of NIOSH [2013]. Current intelligence bulletin 1. Electronically. You may send your information, including each proposed 66: derivation of immediately dangerous comments electronically to http:// extension or reinstatement of an existing to life or health (IDLH) values. www.regulations.gov. Follow the collection of information, before Cincinnati, OH: US Department of instructions for ‘‘Comment or Health and Human Services, Centers for submitting the collection to OMB for Submission’’ or ‘‘More Search Options’’ approval. To comply with this Disease Control and Prevention, National to find the information collection requirement, CMS is publishing this Institute for Occupational Safety and Health, DHHS (NIOSH) Publication document(s) that are accepting notice. 2014–100. comments. 2. By regular mail. You may mail Information Collection John Howard, 1. Type of Information Collection written comments to the following Director, National Institute for Occupational address: CMS, Office of Strategic Request: Extension of a currently Safety and Health, Centers for Disease Control approved information collection; Title and Prevention. Operations and Regulatory Affairs, Division of Regulations Development, of Information Collection: Health Care [FR Doc. 2017–09149 Filed 5–4–17; 8:45 am] Attention: Document Identifier/OMB Reform Insurance Web Portal BILLING CODE 4163–19–P Control Number llll, Room C4–26– Requirements 45 CFR part 159; Use: In 05, 7500 Security Boulevard, Baltimore, accordance with the provisions of the Maryland 21244–1850. ACA referenced above, the U.S. DEPARTMENT OF HEALTH AND To obtain copies of a supporting Department of Health and Human HUMAN SERVICES statement and any related forms for the Services created a Web site called Centers for Medicare & Medicaid proposed collection(s) summarized in healthcare.gov to meet these and other Services this notice, you may make your request provisions of the law, and data using one of following: collection was conducted for six months [Document Identifier: CMS–10320 and CMS– based upon an emergency information 724] 1. Access CMS’ Web site address at collection request. The interim final rule https://www.cms.gov/Regulations-and- published on May 5, 2010 served as the Agency Information Collection Guidance/Legislation/ emergency Federal Register notice for SRADOVICH on DSK3GMQ082PROD with NOTICES Activities: Proposed Collection; PaperworkReductionActof1995/PRA- the prior information collection request. Comment Request Listing.html. The Office of Management and Budget AGENCY: Centers for Medicare & 2. Email your request, including your (OMB) reviewed the request under Medicaid Services, HHS. address, phone number, OMB number, emergency processing and approved it and CMS document identifier, to on April 30, 2010. ACTION: Notice. Paperwork@cms.hhs.gov. CMS updated the web portal system SUMMARY: The Centers for Medicare & 3. Call the Reports Clearance Office at where state Departments of Insurance Medicaid Services (CMS) is announcing (410) 786–1326. and issuers log in using a custom user VerDate Sep<11>2014 17:43 May 04, 2017 Jkt 241001 PO 00000 Frm 00055 Fmt 4703 Sfmt 4703 E:\FR\FM\05MYN1.SGM 05MYN1


Document Created: 2018-11-08 08:39:29
Document Modified: 2018-11-08 08:39:29
CategoryRegulatory Information
CollectionFederal Register
sudoc ClassAE 2.7:
GS 4.107:
AE 2.106:
PublisherOffice of the Federal Register, National Archives and Records Administration
SectionNotices
ActionRequest for information and comments.
DatesElectronic or written comments must be received by June 19, 2017.
ContactG. Scott Dotson, NIOSH, Education and Information Division, 1090 Tusculum Avenue, C-32, Cincinnati, OH 45226, telephone (513) 533-8540 (not a toll free number).
FR Citation82 FR 21239 
2025 Federal Register | Disclaimer | Privacy Policy
USC | CFR | eCFR