82 FR 24062 - Flazasulfuron; Pesticide Tolerances
ENVIRONMENTAL PROTECTION AGENCY Federal Register Volume 82, Issue 100 (May 25, 2017)
Federal Register Volume 82, Issue 100 (May 25, 2017)
| Page Range | 24062-24067 | |
| FR Document | 2017-10763 |
[Federal Register Volume 82, Number 100 (Thursday, May 25, 2017)] [Rules and Regulations] [Pages 24062-24067] From the Federal Register Online [www.thefederalregister.org] [FR Doc No: 2017-10763] ----------------------------------------------------------------------- ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 180 [EPA-HQ-OPP-2016-0112; FRL-9961-54] Flazasulfuron; Pesticide Tolerances AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. ----------------------------------------------------------------------- SUMMARY: This regulation establishes tolerances for residues of flazasulfuron in or on olives. ISK Biosciences Corporation requested these tolerances under the Federal Food, Drug, and Cosmetic Act (FFDCA). DATES: This regulation is effective May 25, 2017. Objections and requests for hearings must be received on or before July 24, 2017, and must be filed in accordance with the instructions provided in 40 CFR part 178 (see also Unit I.C. of the SUPPLEMENTARY INFORMATION). ADDRESSES: The docket for this action, identified by docket identification (ID) number EPA-HQ-OPP-2016-0112, is available at http://www.regulations.gov or at the Office of Pesticide Programs Regulatory Public Docket (OPP Docket) in the Environmental Protection Agency Docket Center (EPA/DC), West William Jefferson Clinton Bldg., Rm. 3334, 1301 Constitution Ave. NW., Washington, DC 20460-0001. The Public Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through Friday, excluding legal holidays. The telephone number for the Public Reading Room is (202) 566-1744, and the telephone number for the OPP Docket is (703) 305-5805. Please review the visitor instructions and additional information about the docket available at http://www.epa.gov/dockets. FOR FURTHER INFORMATION CONTACT: Michael Goodis, Registration Division (7505P), Office of Pesticide Programs, Environmental Protection Agency, 1200 Pennsylvania Ave. NW., Washington, DC 20460-0001; main telephone number: (703) 305-7090; email address: [email protected]. SUPPLEMENTARY INFORMATION: I. General Information A. Does this action apply to me? You may be potentially affected by this action if you are an agricultural producer, food manufacturer, or pesticide manufacturer. The following list of North American Industrial Classification System (NAICS) codes is not intended to be exhaustive, but rather provides a guide to help readers determine whether this document applies to them. Potentially affected entities may include:Crop production (NAICS code 111). Animal production (NAICS code 112). Food manufacturing (NAICS code 311). Pesticide manufacturing (NAICS code 32532). B. How can I get electronic access to other related information? You may access a frequently updated electronic version of EPA's tolerance regulations at 40 CFR part 180 through the Government Printing Office's e-CFR site at http://www.ecfr.gov/cgi-bin/text-idx?&c=ecfr&tpl=/ecfrbrowse/Title40/40tab_02.tpl. C. How can I file an objection or hearing request? Under FFDCA section 408(g), 21 U.S.C. 346a, any person may file an objection to any aspect of this regulation and may also request a hearing on those objections. You must file your objection [[Page 24063]] or request a hearing on this regulation in accordance with the instructions provided in 40 CFR part 178. To ensure proper receipt by EPA, you must identify docket ID number EPA-HQ-OPP-2016-0112 in the subject line on the first page of your submission. All objections and requests for a hearing must be in writing, and must be received by the Hearing Clerk on or before July 24, 2017. Addresses for mail and hand delivery of objections and hearing requests are provided in 40 CFR 178.25(b). In addition to filing an objection or hearing request with the Hearing Clerk as described in 40 CFR part 178, please submit a copy of the filing (excluding any Confidential Business Information (CBI)) for inclusion in the public docket. Information not marked confidential pursuant to 40 CFR part 2 may be disclosed publicly by EPA without prior notice. Submit the non-CBI copy of your objection or hearing request, identified by docket ID number EPA-HQ-OPP-2016-0112, by one of the following methods: Federal eRulemaking Portal: http://www.regulations.gov. Follow the online instructions for submitting comments. Do not submit electronically any information you consider to be CBI or other information whose disclosure is restricted by statute. Mail: OPP Docket, Environmental Protection Agency Docket Center (EPA/DC), (28221T), 1200 Pennsylvania Ave. NW., Washington, DC 20460-0001. Hand Delivery: To make special arrangements for hand delivery or delivery of boxed information, please follow the instructions at http://www.epa.gov/dockets/contacts.html. Additional instructions on commenting or visiting the docket, along with more information about dockets generally, is available at http://www.epa.gov/dockets. II. Summary of Petitioned-For Tolerance In the Federal Register of April 25, 2016 (81 FR 24044) (FRL-9944- 86), EPA issued a document pursuant to FFDCA section 408(d)(3), 21 U.S.C. 346a(d)(3), announcing the filing of a pesticide petition (PP 6F8447) by ISK Biosciences Corporation, 7470 Auburn Road, Suite A, Concord, Ohio 44077. The petition requested that 40 CFR part 180 be amended by establishing tolerances for residues of the herbicide, flazasulfuron (N-[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]-3- (trifluoromethyl)-2-pyridinesulfonamide), in or on olive at 0.01 parts per million (ppm). That document referenced a summary of the petition prepared by ISK Biosciences Corporation, the registrant, which is available in the docket, http://www.regulations.gov. There were no comments received in response to the notice of filing. III. Aggregate Risk Assessment and Determination of Safety Section 408(b)(2)(A)(i) of FFDCA allows EPA to establish a tolerance (the legal limit for a pesticide chemical residue in or on a food) only if EPA determines that the tolerance is ``safe.'' Section 408(b)(2)(A)(ii) of FFDCA defines ``safe'' to mean that ``there is a reasonable certainty that no harm will result from aggregate exposure to the pesticide chemical residue, including all anticipated dietary exposures and all other exposures for which there is reliable information.'' This includes exposure through drinking water and in residential settings, but does not include occupational exposure. Section 408(b)(2)(C) of FFDCA requires EPA to give special consideration to exposure of infants and children to the pesticide chemical residue in establishing a tolerance and to ``ensure that there is a reasonable certainty that no harm will result to infants and children from aggregate exposure to the pesticide chemical residue. . . .'' Consistent with FFDCA section 408(b)(2)(D), and the factors specified in FFDCA section 408(b)(2)(D), EPA has reviewed the available scientific data and other relevant information in support of this action. EPA has sufficient data to assess the hazards of and to make a determination on aggregate exposure for flazasulfuron including exposure resulting from the tolerances established by this action. EPA's assessment of exposures and risks associated with flazasulfuron follows. A. Toxicological Profile EPA has evaluated the available toxicity data and considered its validity, completeness, and reliability as well as the relationship of the results of the studies to human risk. EPA has also considered available information concerning the variability of the sensitivities of major identifiable subgroups of consumers, including infants and children. The risk assessment for flazasulfuron is based on a well- characterized and complete toxicology database. After oral administration to rats, more than 84% of the dose of flazasulfuron was excreted within 72 hours, mostly as parent compound. Urinary elimination accounted for about 80-90% of the dose and fecal elimination for about 10-20%. Females tended to eliminate more in the urine, and slightly more rapidly, than males. Tissue distribution was rapid but incomplete. While levels in tissue were generally low, the tissues with highest concentrations were the blood, liver, and muscle. The liver was the main target organ of flazasulfuron in most species tested, with effects ranging from non-adverse liver hypertrophy to more severe histopathological findings like inflammatory cell infiltration, hepatocellular necrosis and swelling, and bile duct proliferation. Rats also showed kidney toxicity (nephropathy) after chronic exposure. No adverse effects were observed in most short and intermediate duration (<=90 days) studies; only reduced body weight gain and non-adverse liver effects (increased weight and hepatocellular hypertrophy) were observed in some of the subchronic toxicity studies. Developmental toxicity was observed in rats and abortions in rabbits; however, findings in rats were not consistent across strains. A small increase in the incidence of intraventricular septal defect was observed in Wistar rats but not in Sprague-Dawley rats. Significant decreases in mean fetal body weight were observed in both rat strains at the limit dose. In these same studies in the rat, the maternal animals showed no adverse effects. A high incidence of abortion and decreased food consumption, but no specific fetal effects, were observed in rabbits. While the developmental studies indicate there is offspring susceptibility in rats, both rat studies provide clear no- observed-adverse-effect levels (NOAELs) for the adverse fetal effects. Furthermore, the points of departure (PODs) used for risk assessment are lower than doses associated with fetal effects; therefore, the assessments are protective of the observed offspring effects. No increase in tumor incidence was seen in rats or mice. Flazasulfuron is not genotoxic. There was no evidence of neurotoxicity in the database. The acute toxicity data indicate that flazasulfuron has low acute oral, dermal, and inhalation toxicity. It was not found to be a skin irritant, but was a moderate eye irritant. Flazasulfuron was not a dermal sensitizer. Flazasulfuron is classified as ``not likely to be carcinogenic in humans'' based on the lack of carcinogenic effects in the rat and mouse carcinogenicity studies, and lack of a mutagenicity concern. Specific information on the studies received and the nature of the adverse effects caused by flazasulfuron as well as the NOAEL and the lowest-observed- [[Page 24064]] adverse-effect-level (LOAEL) from the toxicity studies can be found at http://www.regulations.gov in document titled ``Flazasulfuron. Aggregate Human Health Risk Assessment for the Proposed New Use on Olives'' at page 23 in docket ID number EPA-HQ-OPP-2016-0112. B. Toxicological Points of Departure/Levels of Concern Once a pesticide's toxicological profile is determined, EPA identifies toxicological POD and levels of concern to use in evaluating the risk posed by human exposure to the pesticide. For hazards that have a threshold below which there is no appreciable risk, the toxicological POD is used as the basis for derivation of reference values for risk assessment. PODs are developed based on a careful analysis of the doses in each toxicological study to determine the dose at which no adverse effects are observed (the NOAEL) and the lowest dose at which adverse effects of concern are identified (the LOAEL). Uncertainty/safety factors are used in conjunction with the POD to calculate a safe exposure level--generally referred to as a population- adjusted dose (PAD) or a reference dose (RfD)--and a safe margin of exposure (MOE). For non-threshold risks, the Agency assumes that any amount of exposure will lead to some degree of risk. Thus, the Agency estimates risk in terms of the probability of an occurrence of the adverse effect expected in a lifetime. For more information on the general principles EPA uses in risk characterization and a complete description of the risk assessment process, see http://www2.epa.gov/pesticide-science-and-assessing-pesticide-risks/assessing-human-health-risk-pesticides. A summary of the toxicological endpoints for flazasulfuron used for human risk assessment is discussed in Unit II. B. of the final rule published in the Federal Register of September 5, 2014 (79 FR 52985) (FRL-9915-32). C. Exposure Assessment 1. Dietary exposure from food and feed uses. In evaluating dietary exposure to flazasulfuron, EPA considered exposure under the petitioned-for tolerances as well as all existing flazasulfuron tolerances in 40 CFR 180.655. EPA assessed dietary exposures from flazasulfuron in food as follows: i. Acute exposure. Quantitative acute dietary exposure and risk assessments are performed for a food-use pesticide, if a toxicological study has indicated the possibility of an effect of concern occurring as a result of a 1-day or single exposure. Such effects were identified for flazasulfuron. In estimating acute dietary exposure, EPA used food consumption information from the United States Department of Agriculture (USDA) under the Continuing Survey of Food Intake by Individuals (CSFII) and the CDC under the National Health and Nutrition Examination Survey/What We Eat in America (NHANES/ WEIA) 2003-2008. The acute dietary exposure analyses incorporate tolerance-level residues of the currently registered and proposed crops combined with 100% crop treated (%CT) to determine the exposure and risk estimates. Residues of flazasulfuron were all http://www2.epa.gov/pesticide-science-and-assessing-pesticide-risks/about-water-exposure-models-used-pesticide. Based on the Pesticide Root Zone Model Ground Water (PRZM GW) for ground water and the Pesticide Root Zone Model/Exposure Analysis Modeling System (PRZM/EXAMS) for surface water, the estimated drinking water concentrations (EDWCs) of flazasulfuron for acute exposures are estimated to be 26.9 parts per billion (ppb) for surface water and 90.8 ppb for ground water. For chronic exposures for non-cancer assessments EDWCs are estimated to be 4.67 ppb for surface water and 55.6 ppb for ground water. Modeled estimates of drinking water concentrations were directly entered into the dietary exposure model. For acute dietary risk assessment, the water concentration value of 90.8 ppb was used to assess the contribution to drinking water. For chronic dietary risk assessment, the water concentration of value 55.6 ppb was used to assess the contribution to drinking water. 3. From non-dietary exposure. The term ``residential exposure'' is used in this document to refer to non-occupational, non-dietary exposure (e.g., for lawn and garden pest control, indoor pest control, termiticides, and flea and tick control on pets). Flazasulfuron is currently registered for use on turf that could result in residential exposures. Residential exposure may occur by the dermal, oral, and inhalation routes of exposures. Flazasulfuron does not pose a dermal hazard; therefore, only inhalation (handler exposure for adults) and oral (post-application incidental oral for children) were assessed. Non-occupational exposures to flazasulfuron are expected to be for short-term durations only. The recommended residential exposure for use in the adult aggregate assessment reflects inhalation exposure from applications to turf via backpack or manually pressurized handwand. The recommended residential exposure for use in the children 1 to <2 years old aggregate assessment reflects hand-to-mouth exposures from post-application exposure to turf treatments. A turf transferable residues (TTR) study is not required for flazasulfuron at this time since there was no dermal hazard [[Page 24065]] identified and the hand-to-mouth MOE is greater than 1,000 based on default values for the fraction of application rate available for transfer after a turf application. Further information regarding EPA standard assumptions and generic inputs for residential exposures may be found at http://www2.epa.gov/pesticide-science-and-assessing-pesticide-risks/standard-operating-procedures-residential-pesticide. 4. Cumulative effects from substances with a common mechanism of toxicity. Section 408(b)(2)(D)(v) of FFDCA requires that, when considering whether to establish, modify, or revoke a tolerance, the Agency consider ``available information'' concerning the cumulative effects of a particular pesticide's residues and ``other substances that have a common mechanism of toxicity.'' In 2016, EPA's Office of Pesticide Programs released a guidance document entitled, ``Pesticide Cumulative Risk Assessment: Framework for Screening Analysis'' https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/pesticide-cumulative-risk-assessment-framework. This document provides guidance on how to screen groups of pesticides for cumulative evaluation using a two-step approach beginning with the evaluation of available toxicological information and if necessary, followed by a risk-based screening approach. This framework supplements the existing guidance documents for establishing common mechanism groups (CMGs) and conducting cumulative risk assessments (CRA). The Agency has utilized this framework for flazasulfuron and determined that although flazasulfuron shares some chemical and/or toxicological characteristics (e.g., chemical structure or apical endpoint) with other pesticides, the toxicological database does not support a testable hypothesis for a common mechanism of action. No further data is required to determine that no common mechanism of toxicity exists for flazasulfuron and other pesticides and no further cumulative evaluation is necessary for flazasulfuron. D. Safety Factor for Infants and Children 1. In general. Section 408(b)(2)(C) of FFDCA provides that EPA shall apply an additional tenfold (10X) margin of safety for infants and children in the case of threshold effects to account for prenatal and postnatal toxicity and the completeness of the database on toxicity and exposure unless EPA determines based on reliable data that a different margin of safety will be safe for infants and children. This additional margin of safety is commonly referred to as the FQPA Safety Factor (SF). In applying this provision, EPA either retains the default value of 10X, or uses a different additional safety factor when reliable data available to EPA support the choice of a different factor. 2. Prenatal and postnatal sensitivity. The available data indicate that flazasulfuron produced developmental effects in the rabbit (increased abortions), and reproductive effects in the rat (decreased pup body weight), only at maternally/parentally toxic dose levels, and these developmental/offspring effects were not more severe than maternal/parental effects (increased abortions the rabbit, increased nephropathy and decreased pup body weight in the rat). While developmental effects (increased incidence of interventricular septal defect and reduced fetal weights) were seen in rats in the absence of maternal toxicity, an indication of quantitative and qualitative susceptibility, clear NOAELs and LOAELs have been established for these adverse fetal effects. Furthermore, the PODs used for risk assessment are lower than doses associated with these developmental effects. Therefore, the assessments are protective of the observed offspring effects, and the Agency has no concerns for quantitative or qualitative susceptibility. 3. Conclusion. EPA has determined that reliable data show the safety of infants and children would be adequately protected if the FQPA SF were reduced to 1X. That decision is based on the following findings: i. The toxicity database for flazasulfuron is complete. ii. An acute neurotoxicity study was conducted with flazasulfuron at dose levels up to 2,000 mg/kg. Mean motor activity measurements at dose levels of 1,000 and 2,000 mg/kg for males and females were statistically significantly decreased from the respective control groups five hours post-dosing. Animals were less active with more resting time than controls. The effect was reversed by the next scheduled observation (Day 7). Neurohistopathologic evaluation did not demonstrate any test material related neurotoxic lesions following the examination of tissues from the central and peripheral nervous systems of high dose and control animals. The NOAEL was 50 mg/kg. A subchronic neurotoxicity study was conducted with flazasulfuron at up to 732 mg/kg bw/day in the diet for 90 days. No biologically relevant neurotoxic effects were observed at the dose levels tested. The available neurotoxicity battery, therefore, did not raise concern for neurotoxicity. Similarly, the subchronic and chronic data in the database did not show any adverse effects that could be considered as neurotoxicity. iii. While there is evidence of increased qualitative and quantitative susceptibility in the young based on rat malformations and decreased fetal weight in two rat developmental toxicity studies, the FQPA Safety Factor is reduced to 1X and is protective of the observed offspring susceptibility because there are clear NOAELs for the developmental effects in the two rat studies developmental toxicity studies and the PODs selected for risk assessment are protective of those effects. iv. There are no residual uncertainties identified in the exposure databases. The exposure databases are complete or are estimated based on data that reasonably account for potential exposures. The acute and chronic dietary food exposure assessment were conservatively based on tolerance-level residues on the currently registered and proposed crops, 100% CT assumptions, and conservative ground water drinking water modeling estimates. The Agency does not believe that the non- dietary residential exposures are underestimated because they are also based on conservative assumptions. All of the exposure estimates are based on conservative assumptions and are not likely to result in underestimated risk. E. Aggregate Risks and Determination of Safety EPA determines whether acute and chronic dietary pesticide exposures are safe by comparing aggregate exposure estimates to the acute PAD (aPAD) and chronic PAD (cPAD). For linear cancer risks, EPA calculates the lifetime probability of acquiring cancer given the estimated aggregate exposure. Short-, intermediate-, and chronic-term risks are evaluated by comparing the estimated aggregate food, water, and residential exposure to the appropriate PODs to ensure that an adequate MOE exists. 1. Acute risk. Using the exposure assumptions discussed in this unit for acute exposure, the acute dietary exposure from food and water to flazasulfuron will occupy 3.1% of the aPAD for infants less than one-year old, the population group receiving the greatest exposure. 2. Chronic risk. Using the exposure assumptions described in this unit for chronic exposure, EPA has concluded that chronic exposure to flazasulfuron from food and water will utilize 23% of [[Page 24066]] the cPAD for infants less than one-year old, the population group receiving the greatest exposure. Based on the explanation in Unit III.C.3., regarding residential use patterns, chronic residential exposure to residues of flazasulfuron is not expected. 3. Short- and intermediate-term aggregate risk. There is potential short-term aggregate exposure to flazasulfuron via the dietary pathway (which is considered background exposure) and the residential pathway (which is considered the primary pathway). Since intermediate-term residential exposures are not likely to occur, intermediate-term aggregate risks were not assessed. Since there is no dermal endpoint, the short-term aggregate exposure assessment for adults includes dietary (food and drinking water) and inhalation handler exposures and results in an aggregate MOE of 1,600. The short-term aggregate exposure assessment for children 1-2 years old includes dietary (food and drinking water) and post-application hand-to-mouth exposure from treated turf and results in an aggregate MOE of 810. Because EPA's level of concern for flazasulfuron is a MOE of 100 or below, these MOEs are not of concern. 4. Aggregate cancer risk for U.S. population. A cancer aggregate risk assessment was not conducted because there was no evidence of carcinogenicity to humans based on lack of carcinogenic effects in the rat and mouse carcinogenicity studies. 5. Determination of safety. Based on these risk assessments, EPA concludes that there is a reasonable certainty that no harm will result to the general population, or to infants and children from aggregate exposure to flazasulfuron residues. IV. Other Considerations A. Analytical Enforcement Methodology An adequate enforcement method is available. The method uses high performance liquid chromatography/tandem mass spectrometry with multiple reaction monitoring (HPLC/MS-MS/MRM). The LOQ is 0.01 ppm. B. International Residue Limits In making its tolerance decisions, EPA seeks to harmonize U.S. tolerances with international standards whenever possible, consistent with U.S. food safety standards and agricultural practices. EPA considers the international maximum residue limits (MRLs) established by the Codex Alimentarius Commission (Codex), as required by FFDCA section 408(b)(4). The Codex Alimentarius is a joint United Nations Food and Agriculture Organization/World Health Organization food standards program, and it is recognized as an international food safety standards-setting organization in trade agreements to which the United States is a party. EPA may establish a tolerance that is different from a Codex MRL; however, FFDCA section 408(b)(4) requires that EPA explain the reasons for departing from the Codex level. The Codex has not established a MRL for flazasulfuron. V. Conclusion Therefore, tolerances are established for residues of flazasulfuron, herbicide, in or on olive at 0.01 ppm. VI. Statutory and Executive Order Reviews This action establishes tolerances under FFDCA section 408(d) in response to a petition submitted to the Agency. The Office of Management and Budget (OMB) has exempted these types of actions from review under Executive Order 12866, entitled ``Regulatory Planning and Review'' (58 FR 51735, October 4, 1993). Because this action has been exempted from review under Executive Order 12866, this action is not subject to Executive Order 13211, entitled ``Actions Concerning Regulations That Significantly Affect Energy Supply, Distribution, or Use'' (66 FR 28355, May 22, 2001) or Executive Order 13045, entitled ``Protection of Children from Environmental Health Risks and Safety Risks'' (62 FR 19885, April 23, 1997). This action does not contain any information collections subject to OMB approval under the Paperwork Reduction Act (PRA) (44 U.S.C. 3501 et seq.), nor does it require any special considerations under Executive Order 12898, entitled ``Federal Actions to Address Environmental Justice in Minority Populations and Low-Income Populations'' (59 FR 7629, February 16, 1994). Since tolerances and exemptions that are established on the basis of a petition under FFDCA section 408(d), such as the tolerance in this final rule, do not require the issuance of a proposed rule, the requirements of the Regulatory Flexibility Act (RFA) (5 U.S.C. 601 et seq.), do not apply. This action directly regulates growers, food processors, food handlers, and food retailers, not States or tribes, nor does this action alter the relationships or distribution of power and responsibilities established by Congress in the preemption provisions of FFDCA section 408(n)(4). As such, the Agency has determined that this action will not have a substantial direct effect on States or tribal governments, on the relationship between the national government and the States or tribal governments, or on the distribution of power and responsibilities among the various levels of government or between the Federal Government and Indian tribes. Thus, the Agency has determined that Executive Order 13132, entitled ``Federalism'' (64 FR 43255, August 10, 1999) and Executive Order 13175, entitled ``Consultation and Coordination with Indian Tribal Governments'' (65 FR 67249, November 9, 2000) do not apply to this action. In addition, this action does not impose any enforceable duty or contain any unfunded mandate as described under Title II of the Unfunded Mandates Reform Act (UMRA) (2 U.S.C. 1501 et seq.). This action does not involve any technical standards that would require Agency consideration of voluntary consensus standards pursuant to section 12(d) of the National Technology Transfer and Advancement Act (NTTAA) (15 U.S.C. 272 note). VII. Congressional Review Act Pursuant to the Congressional Review Act (5 U.S.C. 801 et seq.), EPA will submit a report containing this rule and other required information to the U.S. Senate, the U.S. House of Representatives, and the Comptroller General of the United States prior to publication of the rule in the Federal Register. This action is not a ``major rule'' as defined by 5 U.S.C. 804(2). List of Subjects in 40 CFR Part 180 Environmental protection, Administrative practice and procedure, Agricultural commodities, Pesticides and pests, Reporting and recordkeeping requirements. Dated: April 26, 2017. Michael Goodis, Director, Registration Division, Office of Pesticide Programs. 0 Therefore, 40 CFR chapter I is amended as follows: PART 180--[AMENDED] 0 1. The authority citation for part 180 continues to read as follows: Authority: 21 U.S.C. 321(q), 346a and 371. 0 2. In Sec. 180.655, add alphabetically the entry ``Olive'' to the table in paragraph (a) to read as follows: Sec. 180.655 Flazasulfuron; tolerances for residues. (a) * * * [[Page 24067]] ------------------------------------------------------------------------ Parts per Commodity million ------------------------------------------------------------------------ * * * * * Olive................................................... 0.01 * * * * * ------------------------------------------------------------------------ * * * * * [FR Doc. 2017-10763 Filed 5-24-17; 8:45 am] BILLING CODE 6560-50-P
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(e) * * *
NEW HAMPSHIRE NONREGULATORY
State
Name of nonregulatory Applicable geographic submittal EPA approved Explanations
SIP provision or nonattainment area date/effective date 3
date
* * * * * * *
Infrastructure SIP for Statewide ..................... 12/31/2012 5/25/2017 [Insert Fed- Items that were conditionally approved on 12/
2008 ozone NAAQS. eral Register cita- 16/15 are now fully approved.
tion].
Infrastructure SIP for the Statewide ..................... 11/7/2011 5/25/2017 [Insert Fed- Items that were conditionally approved on 12/
2008 Lead NAAQS. eral Register cita- 16/15 are now fully approved.
tion].
Infrastructure SIP for the Statewide ..................... 1/28/2013 5/25/2017 [Insert Fed- Items that were conditionally approved on 12/
2010 NO2 NAAQS. eral Register cita- 16/15 are now fully approved.
tion].
Infrastructure SIP for the Statewide ..................... 7/13/2013 5/25/2017 [Insert Fed- Items that were conditionally approved on 7/8/
2010 SO2 NAAQS. eral Register cita- 2016 are now fully approved.
tion].
Infrastructure SIP for the Statewide ..................... 7/3/2012 5/25/2017 [Insert Fed- Items that were conditionally approved on 12/
1997 PM2.5 NAAQS. eral Register cita- 16/15 are now fully approved.
tion].
Infrastructure SIP for Statewide ..................... 9/18/2009 5/25/2017 [Insert Fed- Items that were conditionally approved on 12/
2006 PM2.5 NAAQS. eral Register cita- 16/15 are now fully approved.
tion].
* * * * * * *
Transport SIP for the Statewide ..................... 11/17/2015 5/25/2017 [Insert Fed-
2010 NO2 Standard. eral Register cita-
tion].
3 In order to determine the EPA effective date for a specific provision listed in this table, consult the Federal Register notice cited in this col-
umn for the particular provision.
[FR Doc. 2017–09536 Filed 5–24–17; 8:45 am] available at http://www.regulations.gov pesticide manufacturer. The following
BILLING CODE 6560–50–P or at the Office of Pesticide Programs list of North American Industrial
Regulatory Public Docket (OPP Docket) Classification System (NAICS) codes is
in the Environmental Protection Agency not intended to be exhaustive, but rather
ENVIRONMENTAL PROTECTION Docket Center (EPA/DC), West William provides a guide to help readers
AGENCY Jefferson Clinton Bldg., Rm. 3334, 1301 determine whether this document
Constitution Ave. NW., Washington, DC applies to them. Potentially affected
40 CFR Part 180 20460–0001. The Public Reading Room entities may include:
[EPA–HQ–OPP–2016–0112; FRL–9961–54] is open from 8:30 a.m. to 4:30 p.m., • Crop production (NAICS code 111).
Monday through Friday, excluding legal • Animal production (NAICS code
Flazasulfuron; Pesticide Tolerances holidays. The telephone number for the 112).
Public Reading Room is (202) 566–1744, • Food manufacturing (NAICS code
AGENCY: Environmental Protection
and the telephone number for the OPP 311).
Agency (EPA).
Docket is (703) 305–5805. Please review • Pesticide manufacturing (NAICS
ACTION: Final rule. the visitor instructions and additional code 32532).
SUMMARY: This regulation establishes information about the docket available
B. How can I get electronic access to
tolerances for residues of flazasulfuron at http://www.epa.gov/dockets.
other related information?
in or on olives. ISK Biosciences FOR FURTHER INFORMATION CONTACT:
Corporation requested these tolerances Michael Goodis, Registration Division You may access a frequently updated
under the Federal Food, Drug, and (7505P), Office of Pesticide Programs, electronic version of EPA’s tolerance
Cosmetic Act (FFDCA). Environmental Protection Agency, 1200 regulations at 40 CFR part 180 through
Pennsylvania Ave. NW., Washington, the Government Printing Office’s e-CFR
DATES: This regulation is effective May
DC 20460–0001; main telephone site at http://www.ecfr.gov/cgi-bin/text-
25, 2017. Objections and requests for idx?&c=ecfr&tpl=/ecfrbrowse/Title40/
hearings must be received on or before number: (703) 305–7090; email address:
RDFRNotices@epa.gov. 40tab_02.tpl.
July 24, 2017, and must be filed in
accordance with the instructions SUPPLEMENTARY INFORMATION: C. How can I file an objection or hearing
provided in 40 CFR part 178 (see also request?
I. General Information
Unit I.C. of the SUPPLEMENTARY Under FFDCA section 408(g), 21
INFORMATION). A. Does this action apply to me? U.S.C. 346a, any person may file an
ADDRESSES: The docket for this action, You may be potentially affected by objection to any aspect of this regulation
identified by docket identification (ID) this action if you are an agricultural and may also request a hearing on those
number EPA–HQ–OPP–2016–0112, is producer, food manufacturer, or objections. You must file your objection
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or request a hearing on this regulation petition prepared by ISK Biosciences urine, and slightly more rapidly, than
in accordance with the instructions Corporation, the registrant, which is males. Tissue distribution was rapid but
provided in 40 CFR part 178. To ensure available in the docket, http:// incomplete. While levels in tissue were
proper receipt by EPA, you must www.regulations.gov. There were no generally low, the tissues with highest
identify docket ID number EPA–HQ– comments received in response to the concentrations were the blood, liver,
OPP–2016–0112 in the subject line on notice of filing. and muscle.
the first page of your submission. All The liver was the main target organ of
III. Aggregate Risk Assessment and flazasulfuron in most species tested,
objections and requests for a hearing
Determination of Safety with effects ranging from non-adverse
must be in writing, and must be
received by the Hearing Clerk on or Section 408(b)(2)(A)(i) of FFDCA liver hypertrophy to more severe
before July 24, 2017. Addresses for mail allows EPA to establish a tolerance (the histopathological findings like
and hand delivery of objections and legal limit for a pesticide chemical inflammatory cell infiltration,
hearing requests are provided in 40 CFR residue in or on a food) only if EPA hepatocellular necrosis and swelling,
178.25(b). determines that the tolerance is ‘‘safe.’’ and bile duct proliferation. Rats also
In addition to filing an objection or Section 408(b)(2)(A)(ii) of FFDCA showed kidney toxicity (nephropathy)
hearing request with the Hearing Clerk defines ‘‘safe’’ to mean that ‘‘there is a after chronic exposure. No adverse
as described in 40 CFR part 178, please reasonable certainty that no harm will effects were observed in most short and
submit a copy of the filing (excluding result from aggregate exposure to the intermediate duration (≤90 days)
any Confidential Business Information pesticide chemical residue, including studies; only reduced body weight gain
(CBI)) for inclusion in the public docket. all anticipated dietary exposures and all and non-adverse liver effects (increased
Information not marked confidential other exposures for which there is weight and hepatocellular hypertrophy)
pursuant to 40 CFR part 2 may be reliable information.’’ This includes were observed in some of the
disclosed publicly by EPA without prior exposure through drinking water and in subchronic toxicity studies.
notice. Submit the non-CBI copy of your residential settings, but does not include Developmental toxicity was observed
objection or hearing request, identified occupational exposure. Section in rats and abortions in rabbits;
by docket ID number EPA–HQ–OPP– 408(b)(2)(C) of FFDCA requires EPA to however, findings in rats were not
2016–0112, by one of the following give special consideration to exposure consistent across strains. A small
methods: of infants and children to the pesticide increase in the incidence of
• Federal eRulemaking Portal: http:// chemical residue in establishing a intraventricular septal defect was
www.regulations.gov. Follow the online tolerance and to ‘‘ensure that there is a observed in Wistar rats but not in
instructions for submitting comments. reasonable certainty that no harm will Sprague-Dawley rats. Significant
Do not submit electronically any result to infants and children from decreases in mean fetal body weight
information you consider to be CBI or aggregate exposure to the pesticide were observed in both rat strains at the
other information whose disclosure is chemical residue. . . .’’ limit dose. In these same studies in the
restricted by statute. Consistent with FFDCA section rat, the maternal animals showed no
• Mail: OPP Docket, Environmental 408(b)(2)(D), and the factors specified in adverse effects. A high incidence of
Protection Agency Docket Center (EPA/ FFDCA section 408(b)(2)(D), EPA has abortion and decreased food
DC), (28221T), 1200 Pennsylvania Ave. reviewed the available scientific data consumption, but no specific fetal
NW., Washington, DC 20460–0001. and other relevant information in effects, were observed in rabbits. While
• Hand Delivery: To make special support of this action. EPA has the developmental studies indicate
arrangements for hand delivery or sufficient data to assess the hazards of there is offspring susceptibility in rats,
delivery of boxed information, please and to make a determination on both rat studies provide clear no-
follow the instructions at http:// aggregate exposure for flazasulfuron observed-adverse-effect levels (NOAELs)
www.epa.gov/dockets/contacts.html. including exposure resulting from the for the adverse fetal effects.
Additional instructions on commenting tolerances established by this action. Furthermore, the points of departure
or visiting the docket, along with more EPA’s assessment of exposures and risks (PODs) used for risk assessment are
information about dockets generally, is associated with flazasulfuron follows. lower than doses associated with fetal
available at http://www.epa.gov/ effects; therefore, the assessments are
dockets. A. Toxicological Profile protective of the observed offspring
EPA has evaluated the available effects.
II. Summary of Petitioned-For toxicity data and considered its validity, No increase in tumor incidence was
Tolerance completeness, and reliability as well as seen in rats or mice. Flazasulfuron is not
In the Federal Register of April 25, the relationship of the results of the genotoxic. There was no evidence of
2016 (81 FR 24044) (FRL–9944–86), studies to human risk. EPA has also neurotoxicity in the database. The acute
EPA issued a document pursuant to considered available information toxicity data indicate that flazasulfuron
FFDCA section 408(d)(3), 21 U.S.C. concerning the variability of the has low acute oral, dermal, and
346a(d)(3), announcing the filing of a sensitivities of major identifiable inhalation toxicity. It was not found to
pesticide petition (PP 6F8447) by ISK subgroups of consumers, including be a skin irritant, but was a moderate
Biosciences Corporation, 7470 Auburn infants and children. eye irritant. Flazasulfuron was not a
Road, Suite A, Concord, Ohio 44077. The risk assessment for flazasulfuron dermal sensitizer. Flazasulfuron is
The petition requested that 40 CFR part is based on a well-characterized and classified as ‘‘not likely to be
180 be amended by establishing complete toxicology database. After oral carcinogenic in humans’’ based on the
tolerances for residues of the herbicide, administration to rats, more than 84% of lack of carcinogenic effects in the rat
flazasulfuron (N-[[(4,6-dimethoxy-2- the dose of flazasulfuron was excreted and mouse carcinogenicity studies, and
pyrimidinyl)amino]carbonyl]-3- within 72 hours, mostly as parent lack of a mutagenicity concern.
(trifluoromethyl)-2- compound. Urinary elimination Specific information on the studies
pyridinesulfonamide), in or on olive at accounted for about 80–90% of the dose received and the nature of the adverse
0.01 parts per million (ppm). That and fecal elimination for about 10–20%. effects caused by flazasulfuron as well
document referenced a summary of the Females tended to eliminate more in the as the NOAEL and the lowest-observed-
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![24066 Federal Register / Vol. 82, No. 100 / Thursday, May 25, 2017 / Rules and Regulations
the cPAD for infants less than one-year United Nations Food and Agriculture has determined that this action will not
old, the population group receiving the Organization/World Health have a substantial direct effect on States
greatest exposure. Based on the Organization food standards program, or tribal governments, on the
explanation in Unit III.C.3., regarding and it is recognized as an international relationship between the national
residential use patterns, chronic food safety standards-setting government and the States or tribal
residential exposure to residues of organization in trade agreements to governments, or on the distribution of
flazasulfuron is not expected. which the United States is a party. EPA power and responsibilities among the
3. Short- and intermediate-term may establish a tolerance that is various levels of government or between
aggregate risk. There is potential short- different from a Codex MRL; however, the Federal Government and Indian
term aggregate exposure to flazasulfuron FFDCA section 408(b)(4) requires that tribes. Thus, the Agency has determined
via the dietary pathway (which is EPA explain the reasons for departing that Executive Order 13132, entitled
considered background exposure) and from the Codex level. ‘‘Federalism’’ (64 FR 43255, August 10,
the residential pathway (which is The Codex has not established a MRL 1999) and Executive Order 13175,
considered the primary pathway). Since for flazasulfuron. entitled ‘‘Consultation and Coordination
intermediate-term residential exposures V. Conclusion with Indian Tribal Governments’’ (65 FR
are not likely to occur, intermediate- 67249, November 9, 2000) do not apply
term aggregate risks were not assessed. Therefore, tolerances are established to this action. In addition, this action
Since there is no dermal endpoint, the for residues of flazasulfuron, herbicide, does not impose any enforceable duty or
short-term aggregate exposure in or on olive at 0.01 ppm. contain any unfunded mandate as
assessment for adults includes dietary VI. Statutory and Executive Order described under Title II of the Unfunded
(food and drinking water) and Reviews Mandates Reform Act (UMRA) (2 U.S.C.
inhalation handler exposures and This action establishes tolerances 1501 et seq.).
results in an aggregate MOE of 1,600. under FFDCA section 408(d) in This action does not involve any
The short-term aggregate exposure response to a petition submitted to the technical standards that would require
assessment for children 1–2 years old Agency. The Office of Management and Agency consideration of voluntary
includes dietary (food and drinking Budget (OMB) has exempted these types consensus standards pursuant to section
water) and post-application hand-to- of actions from review under Executive 12(d) of the National Technology
mouth exposure from treated turf and Order 12866, entitled ‘‘Regulatory Transfer and Advancement Act
results in an aggregate MOE of 810. Planning and Review’’ (58 FR 51735, (NTTAA) (15 U.S.C. 272 note).
Because EPA’s level of concern for October 4, 1993). Because this action
flazasulfuron is a MOE of 100 or below, VII. Congressional Review Act
has been exempted from review under
these MOEs are not of concern. Executive Order 12866, this action is Pursuant to the Congressional Review
4. Aggregate cancer risk for U.S. not subject to Executive Order 13211, Act (5 U.S.C. 801 et seq.), EPA will
population. A cancer aggregate risk entitled ‘‘Actions Concerning submit a report containing this rule and
assessment was not conducted because Regulations That Significantly Affect other required information to the U.S.
there was no evidence of Energy Supply, Distribution, or Use’’ (66 Senate, the U.S. House of
carcinogenicity to humans based on lack FR 28355, May 22, 2001) or Executive Representatives, and the Comptroller
of carcinogenic effects in the rat and Order 13045, entitled ‘‘Protection of General of the United States prior to
mouse carcinogenicity studies. Children from Environmental Health publication of the rule in the Federal
5. Determination of safety. Based on Risks and Safety Risks’’ (62 FR 19885, Register. This action is not a ‘‘major
these risk assessments, EPA concludes April 23, 1997). This action does not rule’’ as defined by 5 U.S.C. 804(2).
that there is a reasonable certainty that contain any information collections
no harm will result to the general List of Subjects in 40 CFR Part 180
subject to OMB approval under the
population, or to infants and children Paperwork Reduction Act (PRA) (44 Environmental protection,
from aggregate exposure to flazasulfuron U.S.C. 3501 et seq.), nor does it require Administrative practice and procedure,
residues. any special considerations under Agricultural commodities, Pesticides
IV. Other Considerations Executive Order 12898, entitled and pests, Reporting and recordkeeping
‘‘Federal Actions to Address requirements.
A. Analytical Enforcement Methodology Environmental Justice in Minority Dated: April 26, 2017.
An adequate enforcement method is Populations and Low-Income Michael Goodis,
available. The method uses high Populations’’ (59 FR 7629, February 16, Director, Registration Division, Office of
performance liquid chromatography/ 1994). Pesticide Programs.
tandem mass spectrometry with Since tolerances and exemptions that
multiple reaction monitoring (HPLC/ are established on the basis of a petition ■Therefore, 40 CFR chapter I is
MS–MS/MRM). The LOQ is 0.01 ppm. under FFDCA section 408(d), such as amended as follows:
the tolerance in this final rule, do not
B. International Residue Limits PART 180—[AMENDED]
require the issuance of a proposed rule,
In making its tolerance decisions, EPA the requirements of the Regulatory ■ 1. The authority citation for part 180
seeks to harmonize U.S. tolerances with Flexibility Act (RFA) (5 U.S.C. 601 et continues to read as follows:
international standards whenever seq.), do not apply.
possible, consistent with U.S. food This action directly regulates growers, Authority: 21 U.S.C. 321(q), 346a and 371.
safety standards and agricultural food processors, food handlers, and food ■ 2. In § 180.655, add alphabetically the
practices. EPA considers the retailers, not States or tribes, nor does entry ‘‘Olive’’ to the table in paragraph
international maximum residue limits this action alter the relationships or (a) to read as follows:
(MRLs) established by the Codex distribution of power and
Alimentarius Commission (Codex), as responsibilities established by Congress § 180.655 Flazasulfuron; tolerances for
required by FFDCA section 408(b)(4). in the preemption provisions of FFDCA residues.
The Codex Alimentarius is a joint section 408(n)(4). As such, the Agency (a) * * *
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![Federal Register / Vol. 82, No. 100 / Thursday, May 25, 2017 / Rules and Regulations 24067
Parts per SUPPLEMENTARY INFORMATION: • Federal eRulemaking Portal: http://
Commodity million www.regulations.gov. Follow the online
I. General Information
instructions for submitting comments.
A. Does this action apply to me? Do not submit electronically any
* * * * * information you consider to be CBI or
Olive ...................................... 0.01 You may be potentially affected by
other information whose disclosure is
this action if you are an agricultural
restricted by statute.
* * * * * producer, food manufacturer, or
• Mail: OPP Docket, Environmental
pesticide manufacturer. The following Protection Agency Docket Center (EPA/
* * * * * list of North American Industrial
[FR Doc. 2017–10763 Filed 5–24–17; 8:45 am] DC), (28221T), 1200 Pennsylvania Ave.
Classification System (NAICS) codes is NW., Washington, DC 20460–0001.
BILLING CODE 6560–50–P not intended to be exhaustive, but rather • Hand Delivery: To make special
provides a guide to help readers arrangements for hand delivery or
determine whether this document delivery of boxed information, please
ENVIRONMENTAL PROTECTION applies to them. Potentially affected
AGENCY follow the instructions at http://
entities may include: www.epa.gov/dockets/contacts.html.
• Crop production (NAICS code 111). Additional instructions on commenting
40 CFR Part 180
• Animal production (NAICS code or visiting the docket, along with more
[EPA–HQ–OPP–2016–0029 FRL–9961–99] 112). information about dockets generally, is
• Food manufacturing (NAICS code available at http://www.epa.gov/
Fenazaquin; Pesticide Tolerances 311). dockets.
AGENCY: Environmental Protection • Pesticide manufacturing (NAICS
code 32532). II. Summary of Petitioned-For
Agency (EPA). Tolerances
ACTION: Final rule. B. How can I get electronic access to
In the Federal Registers of March 16,
other related information?
SUMMARY: This regulation establishes 2016 (81 FR 14030) (FRL–9942–86);
tolerances for residues of fenazaquin in You may access a frequently updated May 19, 2016 (81 FR 31581) (FRL–9946–
or on hop, dried cones; nuts, tree, group electronic version of EPA’s tolerance 02); and August 12, 2016 (81 FR 53379)
14–12; pineapple; and tea, dried. Gowan regulations at 40 CFR part 180 through (FRL–9949–53) EPA issued documents
Company requested these tolerances the Government Printing Office’s e-CFR pursuant to FFDCA section 408(d)(3), 21
under the Federal Food, Drug, and site at http://www.ecfr.gov/cgi-bin/text- U.S.C. 346a(d)(3), announcing the filing
Cosmetic Act (FFDCA). idx?&c=ecfr&tpl=/ecfrbrowse/Title40/ of pesticide petitions (PP 6F8442, PP
DATES: This regulation is effective May 40tab_02.tpl. 5F8429, and PP 6E8466) by Gowan
25, 2017. Objections and requests for C. How can I file an objection or hearing Company, P.O. Box 5569, Yuma, AZ
hearings must be received on or before request? 85366–5569. The petitions requested
July 24, 2017, and must be filed in that 40 CFR 180.632 be amended by
Under FFDCA section 408(g), 21 establishing tolerances for residues of
accordance with the instructions
U.S.C. 346a, any person may file an the miticide/insecticide fenazaquin, 4-
provided in 40 CFR part 178 (see also
objection to any aspect of this regulation [2-[4-(1,1-dimethylethyl)
Unit I.C. of the SUPPLEMENTARY
and may also request a hearing on those phenyl]ethoxy]quinazoline, in or on
INFORMATION).
objections. You must file your objection hops at 30 parts per million (ppm) (PP
ADDRESSES: The docket for this action, or request a hearing on this regulation 6F8442); nuts, tree, group 14–12 at 0.02
identified by docket identification (ID) in accordance with the instructions ppm (PP 5F8429); pineapple at 0.2 ppm
number EPA–HQ–OPP–2016–0029, is provided in 40 CFR part 178. To ensure (PP 6E8466); and tea at 9 ppm (PP
available at http://www.regulations.gov proper receipt by EPA, you must 6E8466). The petitions also requested
or at the Office of Pesticide Programs identify docket ID number EPA–HQ– that the existing tolerance for almond at
Regulatory Public Docket (OPP Docket) OPP–2016–0029 in the subject line on 0.2 ppm be removed upon
in the Environmental Protection Agency the first page of your submission. All establishment of the above tolerance for
Docket Center (EPA/DC), West William objections and requests for a hearing nut, tree group 14–12. Those documents
Jefferson Clinton Bldg., Rm. 3334, 1301 must be in writing, and must be referenced summaries of the petitions
Constitution Ave. NW., Washington, DC received by the Hearing Clerk on or prepared by Gowan Company, the
20460–0001. The Public Reading Room before July 24, 2017. Addresses for mail registrant, which are available in the
is open from 8:30 a.m. to 4:30 p.m., and hand delivery of objections and docket, http://www.regulations.gov.
Monday through Friday, excluding legal hearing requests are provided in 40 CFR Comments were received on the Notices
holidays. The telephone number for the 178.25(b). of Filing. EPA’s response to these
Public Reading Room is (202) 566–1744, In addition to filing an objection or comments is discussed in Unit IV.C.
and the telephone number for the OPP hearing request with the Hearing Clerk
Docket is (703) 305–5805. Please review as described in 40 CFR part 178, please III. Aggregate Risk Assessment and
the visitor instructions and additional submit a copy of the filing (excluding Determination of Safety
information about the docket available any Confidential Business Information Section 408(b)(2)(A)(i) of FFDCA
at http://www.epa.gov/dockets. (CBI)) for inclusion in the public docket. allows EPA to establish a tolerance (the
FOR FURTHER INFORMATION CONTACT: Information not marked confidential legal limit for a pesticide chemical
Michael Goodis, Registration Division pursuant to 40 CFR part 2 may be residue in or on a food) only if EPA
(7505P), Office of Pesticide Programs, disclosed publicly by EPA without prior determines that the tolerance is ‘‘safe.’’
Environmental Protection Agency, 1200 notice. Submit the non-CBI copy of your Section 408(b)(2)(A)(ii) of FFDCA
Pennsylvania Ave. NW., Washington, objection or hearing request, identified defines ‘‘safe’’ to mean that ‘‘there is a
DC 20460–0001; main telephone by docket ID number EPA–HQ–OPP– reasonable certainty that no harm will
number: (703) 305–7090; email address: 2016–0029, by one of the following result from aggregate exposure to the
RDFRNotices@epa.gov. methods: pesticide chemical residue, including
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Document Created: 2018-11-08 08:52:41
Document Modified: 2018-11-08 08:52:41
| Category | Regulatory Information | |
| Collection | Federal Register | |
| sudoc Class | AE 2.7: GS 4.107: AE 2.106: | |
| Publisher | Office of the Federal Register, National Archives and Records Administration | |
| Section | Rules and Regulations | |
| Action | Final rule. | |
| Dates | This regulation is effective May 25, 2017. Objections and requests for hearings must be received on or before July 24, 2017, and must be filed in accordance with the instructions provided in 40 CFR part 178 (see also Unit I.C. of the SUPPLEMENTARY INFORMATION). | |
| Contact | Michael Goodis, Registration Division (7505P), Office of Pesticide Programs, Environmental Protection Agency, 1200 Pennsylvania Ave. NW., Washington, DC 20460-0001; main telephone | |
| FR Citation | 82 FR 24062 | |
| CFR Associated | Environmental Protection; Administrative Practice and Procedure; Agricultural Commodities; Pesticides and Pests and Reporting and Recordkeeping Requirements |
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