Significant New Use Rules on Certain Chemical Substances (25-3.5e)
EPA is issuing significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for certain chemical substances that were the subject of premanufacture notices (P...
EPA is issuing significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for certain chemical substances that were the subject of premanufacture notices (PMNs) and are also subject to an Order issued by EPA pursuant to TSCA. The SNURs require persons to notify EPA at least 90 days before commencing the manufacture (defined by statute to include import) or processing of any of these chemical substances for an activity that is designated as a significant new use in the SNUR. The required notification initiates EPA's evaluation of the conditions of that use for that chemical substance. In addition, the manufacture or processing for the significant new use may not commence until EPA has conducted a review of the required notification; made an appropriate determination regarding that notification; and taken such actions as required by that determination.
DATES:
This rule is effective on January 4, 2027. For purposes of judicial review, this rule shall be promulgated at 1 p.m. (EST) on November 19, 2026.
ADDRESSES:
The docket for this action, identified under docket identification (ID) number EPA-HQ-OPPT-2025-2169, is available online at
www.regulations.gov
or in person at the Office of Pollution Prevention and Toxics Docket (OPPT Docket) in the Environmental Protection Agency Docket Center (EPA/DC). Please review the visitor instructions and additional information about the docket available at
www.epa.gov/dockets.
FOR FURTHER INFORMATION CONTACT:
For technical information:
Joseph Said, New Chemicals Division (7405M), Office of Pollution Prevention and Toxics, Environmental Protection Agency, 1200 Pennsylvania Ave. NW, Washington, DC 20460-0001; telephone number: (202) 566-0848; email address:
said.joseph@epa.gov.
For general information on SNURs:
Iliriana Mushkolaj, New Chemicals Division (7405M), Office of Pollution Prevention and Toxics, Environmental Protection Agency, 1200 Pennsylvania Ave. NW, Washington, DC 20460-0001; telephone number: (202) 564-6877; email address:
mushkolaj.iliriana@epa.gov.
For general information on TSCA:
The TSCA Assistance Information Service Hotline, Goodwill of the Finger Lakes, 422 South Clinton Ave., Rochester, NY 14620; telephone number: (202) 554-1404; email address:
TSCA-Hotline@epa.gov.
SUPPLEMENTARY INFORMATION:
I. Executive Summary
A. What is the Agency's authority for taking this action?
TSCA section 5(a)(2) (15 U.S.C. 2604(a)(2)) authorizes EPA to determine that a use of a chemical substance is a “significant new use.” EPA must make this determination by rule after considering all relevant factors, including the factors in TSCA section 5(a)(2).
B. What action is the Agency taking?
EPA is finalizing SNURs under TSCA section 5(a)(2) for the chemical substances identified in this document. These chemical substances were the subject of PMNs and are also subject to an Order issued by EPA pursuant to TSCA section 5(e)(1)(A), as required by the determinations made under TSCA section 5(a)(3)(B). The SNURs identify as significant new uses any manufacturing, processing, use, distribution in commerce, or disposal that does not conform to the restrictions imposed by the underlying TSCA Orders, consistent with TSCA section 5(f)(4). The SNURs require persons who intend to manufacture or process any of these chemical substances for an activity that is designated as a significant new use in the SNURs to notify EPA at least 90 days before commencing that activity.
Previously, EPA proposed SNURs for these chemical substances in the
Federal Register
of June 5, 2026 (91 FR 34480 (FRL-13126-01-OCSPP)). The docket includes information considered by the Agency in developing the proposed and final rules, including public comments and EPA's responses to the comments received as discussed in Unit II.D.
C. Does this action apply to me?
1. General Applicability
This action applies to you if you manufacture, process, or use the chemical substances identified in this document. The following list of North American Industrial Classification System (NAICS) codes is not intended to be exhaustive, but rather provides a guide to help readers determine whether this document applies to them. Potentially affected entities may include:
Manufacturers or processors of one or more subject chemical substances (NAICS codes 325 and 324110),e.g.,
chemical manufacturing and petroleum refineries.
2. Applicability to Importers and Exporters
This action may also apply to certain entities through pre-existing import certification and export notification requirements under TSCA (
www.epa.gov/tsca-import-export-requirements).
Chemical importers are subject to TSCA section 13 (15 U.S.C. 2612), the requirements in 19 CFR 12.118 through 12.127, 19 CFR 127.28, and 40 CFR part 707, subpart B. Importers of chemical substances in bulk form, as part of a mixture, or as part of an article (if required by rule) must certify that the shipment of the chemical substance complies with all applicable rules and orders under TSCA, including regulations issued under TSCA sections 5, 6, 7 and Title IV.
Pursuant to 40 CFR 721.20, any persons who export or intend to export a chemical substance identified in this document are subject to the export notification provisions of TSCA section 12(b) (15 U.S.C. 2611(b)) and must comply with the export notification requirements in 40 CFR part 707, subpart D.
D. What are the incremental economic impacts of this action?
EPA has evaluated the potential costs of establishing SNUN reporting requirements for potential manufacturers and processors of the chemical substances identified in this
( printed page 69705)
document. This analysis, which is available in the docket, is briefly summarized here.
1. Estimated Costs for SNUN Submissions
A SNUR requires that any person who intends to engage in such activity in the future must first notify EPA by submitting a SNUN. If a SNUN is submitted, costs are an estimated $45,000 per SNUN submission for large business submitters and $14,500 for small business submitters. These estimates include the cost to prepare and submit the SNUN (including registration for EPA's Central Data Exchange (CDX)), and the payment of a user fee. Businesses that submit a SNUN would be subject to either a $37,000 user fee required by 40 CFR 700.45(c)(2)(ii) and (d), or, if they are a small business as defined at 13 CFR 121.201, a reduced user fee of $6,480 (40 CFR 700.45(c)(1)(ii) and (d)). These estimates reflect the costs and fees as they are known at the time of this rulemaking.
2. Estimated Costs for Export Notifications
EPA has also evaluated the potential costs associated with the pre-existing export notification requirements under TSCA section 12(b) and the implementing regulations at 40 CFR part 707, subpart D. For persons exporting a substance that is the subject of a SNUR, a one-time notice to EPA must be provided for the first export or intended export to a particular country. The total costs of export notification will vary by chemical, depending on the number of required notifications (
i.e.,
the number of countries to which the chemical is exported). While EPA is unable to make any estimate of the likely number of export notifications for the chemical substances covered by these SNURs, as stated in the accompanying economic analysis, the estimated cost of the export notification requirement on a per unit basis is approximately $106.
B. Applicability of the Significant New Use Designation
To establish a significant new use, EPA must determine that the use is not ongoing. As discussed in Unit II.E. of the proposed rule, EPA concluded that the proposed significant new uses were not ongoing. If EPA subsequently determines that such a use was ongoing as of the date of publication of the proposed rule and did not cease prior to issuance of the final rule, EPA will not designate that use as a significant new use in the final rule. EPA has no information to suggest that any of the significant new uses identified in this rule meet this criterion.
As discussed in the
Federal Register
of April 24, 1990 (55 FR 17376 (FRL-3658-5)), EPA believes that the intent of TSCA section 5(a)(1)(B) is best served by designating a use as a significant new use as of the date of publication of the proposed rule rather than as of the effective date of the final rule. The objective of EPA's approach is to ensure that a person cannot impede finalization of a SNUR by initiating a significant new use after publication of the proposed rule but before the effective date of the final rule. Uses arising after the publication of the proposed rule are distinguished from uses that are identified in the final rule as having been ongoing on the date of publication of the proposed rule. The former would be new uses, the latter ongoing uses, except that uses that are identified as ongoing as of the publication of the proposed rule would not be considered ongoing uses if they have ceased by the date of issuance of a final rule.
In the unlikely event that before a final rule becomes effective a person begins commercial manufacturing (including importing) or processing of the chemical substances for a use that is designated as a significant new use in that final rule, such a person would have to cease any such activity upon the effective date of the final rule. To resume their activities, these persons would have to first comply with all applicable SNUR notification requirements and wait until all TSCA prerequisites for the commencement of manufacture or processing have been satisfied.
Issuance of a SNUR for a chemical substance does not signify that the chemical substance is listed on the TSCA Chemical Substance Inventory (TSCA Inventory). Guidance on how to determine if a chemical substance is on the TSCA Inventory is available on the internet at
www.epa.gov/tsca-inventory.
EPA recognizes that TSCA section 5 does not require development of any particular new information (
e.g.,
generating test data) before submission of a SNUN. There is an exception: If a person is required to submit information for a chemical substance pursuant to a rule, order or consent agreement under TSCA section 4, then TSCA section 5(b)(1)(A) requires such information to be submitted to EPA at the time of submission of the SNUN.
In the absence of a rule, TSCA order, or consent agreement under TSCA section 4 covering the chemical substance, persons are required only to submit information in their possession or control and to describe any other information known to or reasonably ascertainable by them (see 40 CFR 720.50). However, upon review of PMNs and SNUNs, the Agency has the authority to require appropriate testing. To assist with EPA's analysis of the SNUN, submitters are encouraged, but not required, to provide the potentially useful information as identified for the chemical substance in Unit III.C. of the proposed rule.
EPA strongly encourages persons, before performing any testing, to consult with the Agency pertaining to protocol selection. Furthermore, pursuant to TSCA section 4(h), which pertains to reduction of testing in vertebrate animals, EPA encourages consultation with the Agency on the use of alternative test methods and strategies (also called New Approach Methodologies, or NAMs), if available, to generate the recommended test data. EPA encourages dialog with Agency representatives to help determine how best the submitter can meet both the data needs and the objective of TSCA section 4(h). For more information on alternative test methods and strategies to reduce vertebrate animal testing, visit
www.epa.gov/assessing-and-managing-chemicals-under-tsca/alternative-test-methods-and-strategies-reduce.
The potentially useful information described in Unit III. of the proposed rule may not be the only means of providing information to evaluate the chemical substance associated with the significant new uses. However, submitting a SNUN without any test data may increase the likelihood that
( printed page 69706)
EPA will take action under TSCA sections 5(e) or 5(f). EPA recommends that potential SNUN submitters contact EPA early enough so that they will be able to conduct the appropriate tests.
SNUN submitters should be aware that EPA will be better able to evaluate SNUNs which provide detailed information about human exposure and environmental release that may result from the significant new use of the chemical substances.
D. Public Comments on Proposed Rule and EPA Responses
EPA received public comments on the proposed SNURs and prepared a Response to Comment document that provides the Agency responses. The comments and the Response to Comment document are available in the docket. As described in the Response to Comment document, EPA is finalizing these SNURs or has already finalized a SNUR in a separate action as proposed.
III. Chemical Substances Subject to These SNURs
A. What is the designated cutoff date for ongoing uses?
EPA designates the date of publication of the proposed rule as the cutoff date for determining whether the new use is ongoing,
i.e.,
June 5, 2026 (91 FR 34480 (FRL-13126-01-OCSPP)). This designation is explained in more detail in Unit II.B.
B. What information was provided for each chemical substance?
In Unit III.C. of the proposed rule, EPA provided the following information for each chemical substance subject to these SNURs:
PMN number (the CFR citation assigned in the regulatory text section of this document).
Chemical name (generic name, if the specific name is claimed as CBI).
Chemical Abstracts Service Registry Number (CASRN) or Accession Number (if assigned, for confidential chemical identities).
Basis for the SNUR (e.g.,
effective date of and basis for the TSCA Order).
Potentially useful information.
The regulatory text section of this document specifies the chemical substances and activities designated as significant new uses. Certain new uses, including production volume limits and other uses designated, may be claimed as CBI, as discussed in more detail in Unit II.C. of the proposed rule.
In addition, as discussed in Unit III.B. of the proposed rule, these SNURs include PMN substances that are subject to orders issued under TSCA section 5(e)(1)(A), as required by the determinations made under TSCA section 5(a)(3)(B). Those TSCA Orders require protective measures to limit exposures or otherwise mitigate the potential unreasonable risk. As such, the SNURs identify as significant new uses any manufacturing, processing, use, distribution in commerce, or disposal that does not conform to the restrictions imposed by the underlying TSCA Orders, consistent with TSCA section 5(f)(4).
This action establishes SNURs for new chemical substances that were the subject of PMNs. The Office of Management and Budget (OMB) has exempted these types of actions from review under Executive Order 12866 (58 FR 51735, October 4, 1993).
According to the PRA (44 U.S.C. 3501et seq.), an agency may not conduct or sponsor, and a person is not required to respond to a collection of information that requires OMB approval under PRA, unless it has been approved by OMB and displays a currently valid OMB control number. The OMB control numbers for EPA's regulations in title 40 of the CFR, after appearing in the
Federal Register
, are listed in 40 CFR part 9, and included on the related collection instrument or form, if applicable.
The information collection requirements related to SNURs have already been approved by OMB pursuant to PRA under OMB control number 2070-0038 (EPA ICR No. 1188). This action does not impose any burden requiring additional OMB approval. If an entity were to submit a SNUN to the Agency, the annual burden is estimated to average between 30 and 170 hours per submission. This burden estimate includes the time needed to review instructions, search existing data sources, gather and maintain the data needed, and complete, review, and submit the required SNUN.
D. Regulatory Flexibility Act (RFA)
I certify that this action will not have a significant economic impact on a substantial number of small entities under the RFA (5 U.S.C. 601et seq.). The requirement to submit a SNUN applies to any person (including small or large entities) who intends to engage in any activity described in the final rule as a “significant new use.” Because these uses are “new,” based on all information currently available to EPA, EPA has concluded that no small or large entities presently engage in such activities.
A SNUR requires that any person who intends to engage in such activity in the future must first notify EPA by submitting a SNUN. Although some small entities may decide to pursue a significant new use in the future, EPA cannot presently determine how many, if any, there may be. However, EPA's experience to date is that, in response to the promulgation of SNURs covering over 1,000 chemicals, the Agency receives only a small number of notices per year. For example, the number of SNUNs received was 7 in Federal fiscal year (FY) 2020, 9 in FY2021, 9 in FY2022, 23 in FY2023, and 7 in FY2024, and only a fraction of these submissions were from small businesses.
In addition, the Agency currently offers relief to qualifying small businesses by reducing the SNUN submission fee from $37,000 to $6,480. This lower fee reduces the total reporting and recordkeeping cost of submitting a SNUN to about $14,500 per SNUN submission for qualifying small firms. Therefore, the potential economic impacts of complying with these proposed SNURs are not expected to be significant or adversely impact a substantial number of small entities. In a SNUR that published in the
Federal Register
of June 2, 1997 (62 FR 29684 (FRL-5597-1)), the Agency presented its general determination that SNURs are not expected to have a significant economic impact on a substantial number of small entities, which was provided to the Chief Counsel for Advocacy of the Small Business Administration.
E. Unfunded Mandates Reform Act (UMRA)
This action does not contain an unfunded mandate of $100 million or more (in 1995 dollars) in any one year as described in UMRA, 2 U.S.C. 1531-1538, and does not significantly or uniquely affect small governments.
( printed page 69707)
Based on EPA's experience with proposing and finalizing SNURs, State, local, and Tribal governments have not been impacted by SNURs, and EPA does not have any reasons to believe that any State, local, or Tribal government will be impacted by these SNURs. In addition, the estimated costs of this action to the private sector do not exceed $183 million or more in any one year (the 1995 dollars are adjusted to 2023 dollars for inflation using the GDP implicit price deflator). The estimated costs for this action are discussed in Unit I.D.
This action will not have federalism implications as specified in Executive Order 13132 (64 FR 43255, August 10, 1999), because it is not expected to have a substantial direct effect on States, on the relationship between the national government and the States, or on the distribution of power and responsibilities among the various levels of government. Accordingly, the requirements of Executive Order 13132 do not apply to this action.
G. Executive Order 13175: Consultation and Coordination With Indian Tribal Governments
This action will not have Tribal implications as specified in Executive Order 13175 (65 FR 67249, November 9, 2000), because it is not expected to have substantial direct effects on Indian Tribes, significantly or uniquely affect the communities of Indian Tribal governments and does not involve or impose any requirements that affect Indian Tribes. Accordingly, the requirements of Executive Order 13175 do not apply to this action.
H. Executive Order 13045: Protection of Children From Environmental Health Risks and Safety Risks
This action is not subject to Executive Order 13045 (62 FR 19885, April 23, 1997), because it does not concern an environmental health or safety risk. Since this action does not concern a human health risk, EPA's 2026 Policy on Children's Health also does not apply. Although the establishment of these SNURs do not address an existing children's environmental health concern because the chemical uses involved are not ongoing uses, SNURs require that persons notify EPA at least 90 days before commencing manufacture (defined by statute to include import) or processing of the identified chemical substances for an activity that is designated as a significant new use by the SNUR. This notification allows EPA to assess the intended uses to identify potential risks and take appropriate actions before the activities commence.
I. Executive Order 13211: Actions Concerning Regulations That Significantly Affect Energy Supply, Distribution, or Use
This action is not a “significant energy action” as defined in Executive Order 13211 (66 FR 28355, May 22, 2001), because it is not likely to have a significant adverse effect on the supply, distribution, or use of energy.
J. National Technology Transfer and Advancement Act (NTTAA)
This action does not involve any technical standards subject to NTTAA section 12(d) (15 U.S.C. 272 note).
K. Congressional Review Act (CRA)
This action is subject to the CRA (5 U.S.C. 801et seq.), and EPA will submit a rule report to each House of the Congress and to the Comptroller General of the United States. This action is not a “major rule” as defined by 5 U.S.C. 804(2).
Substitutedheterocyclic onium compound, salt with fluoropolysubstitutedalkyl substitutedtricycloalkane carboxylate (1:1), polymer with 4-ethenyl-2-methoxylphenol and fluorosubstitutedaromaticalkyl 2-methyl-2-propenoate, di-Me 2,2′-(1,2-diazenediyl)bis[2- methylpropanoate]-initiated (generic).
Dibenzothiophenium, 5-phenyl-, salt with fluoroheterosubstitutedalkyl
( printed page 69708)
heterosubstitutedhalosubstitutedaromatichydrocarboncarboxylate (1:1), polymer with 3- ethenylphenol and fluorocarbomonocyclealkyl 2-methyl-2-propenoate (generic).
Dibenzothiophenium, 5-phenyl-, salt with fluoroheterosubstitutedalkyl heterosubstitutedhalosubstitutedaromatichydrocarboncarboxylate (1:1), polymer with 3- ethenylphenol and alkylcycloalkyl 2-methyl-2-propenoate (generic).
Sulfonium, bis(dihalo carbomonocycle)carbomonocycle-. salt with dihalo-sulfoalkyl [(alkenylcarbomonocycle)substituted] trisubstituted benzoate, polymer with alkenylcarbomonocycle and alkylcarbomonocycle alkyl alkenoate (generic).
Sulfonium, bis(dihalo carbomonocycle)(halo carbomonocycle)-, salt with dihalo-sulfoalkyl [(alkenylcarbomonocycle)substituted] trisubstituted benzoate, polymer with alkenylcarbomonocycle and alkylcarbomonocycle alkyl alkenoate (generic).
Alcohols, C16-18 and C18-unsatd., reaction products with substituted alkyloxirane and alkyl acid (generic).
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as alcohols, C16-18 and C18-unsatd., reaction products with substituted alkyloxirane and alkyl acid (PMN P-21-76) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1) and (a)(3) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1) and (5). For purposes of § 721.72(g)(1), this substance may cause: skin sensitization and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(o). It is a significant new use to manufacture, process, or use the substance in any manner that results in inhalation exposure.
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified as manganate(4-), hexakis(cyano-.kappa.C)-, manganese(2+) sodium, (OC-6-11)- (PMN P-22-40; CAS No. 2073840-04-5) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into an article.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1), (a)(3) through (6), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health (NIOSH) assigned protection factor (APF) of at least 1000.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For purposes of § 721.72(g)(1), this substance may cause: acute toxicity, skin sensitization, reproductive toxicity, and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(b) and (c). For purposes of § 721.80(b) and (c), the process remains enclosed as long as the only releases are from sampling, dust filter changes, loss of integrity or failure of the manufacturing process equipment or control systems. It is a significant new use to use the substance other than as a component in manufacture of high-performance batteries. It is a significant new use to use the substance in any manner that results in inhalation exposure to workers. It is a significant new use to perform the dust filter change more than two times a year. It is a significant new use to manufacture the substance at a site that has off-gas waste streams unless all such waste streams are captured and routed through engineering controls that achieve a total combined efficiency of 99.9% destruction of the substance. It is a significant new use to manufacture the substance unless the concentration of manganese does not exceed the confidential percentage by weight listed in the Order.
(iv)
Disposal.
It is a significant new use to dispose of the substance, when not in solid form, by landfill. The substance may be disposed of by landfill at hazardous waste landfill facilities that are in compliance with RCRA subtitle C and D, when in solid form. The substance or waste streams containing the substance must be disposed of by incineration, when not in solid form. It is a significant new use to exceed the confidential disposal by incineration limit listed in the Order. This limit does
( printed page 69709)
not apply to quantities sent for incineration at a hazardous waste incineration facility that is compliant with RCRA subtitle C.
(v)
Release to water.
Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N=0.2.
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified as ferrate(4-), hexakis(cyano-.kappa.C)-, iron(3+) manganese(2+) sodium, (OC-6-11)- (PMN P-22-41; CAS No. 2073839-30-0) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into an article.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1), (a)(3) through (6), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health (NIOSH) assigned protection factor (APF) of at least 10.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For purposes of § 721.72(g)(1), this substance may cause: acute toxicity, skin sensitization, reproductive toxicity, and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(b) and (c). For purposes of § 721.80(b) and (c), the process remains enclosed as long as the only releases are from sampling, dust filter changes, loss of integrity or failure of the manufacturing process equipment or control systems. It is a significant new use to use the substance other than as a component in manufacture of high-performance batteries. It is a significant new use to use the substance in any manner that results in inhalation exposure to workers. It is a significant new use to perform the dust filter change more than two times a year. It is a significant new use to manufacture the substance at a site that has off-gas waste streams unless all such waste streams are captured and routed through engineering controls that achieve a total combined efficiency of 99.9% destruction of the substance. It is a significant new use to manufacture the substance unless the concentration of manganese does not exceed the confidential percentage by weight listed in the Order.
(iv)
Disposal.
It is a significant new use to dispose of the substance, when not in solid form, by landfill. The substance may be disposed of by landfill at hazardous waste landfill at a facility that is in compliance with RCRA subtitle C and D, when in solid form. The substance or waste streams containing the substance must be disposed of by incineration, when not in solid form. It is a significant new use to exceed the confidential disposal by incineration limit listed in the Order. This limit does not apply to quantities sent for incineration at a hazardous waste incineration facility that is compliant with RCRA subtitle C.
(v)
Release to water.
Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N = 2.
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section
except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
(a) Chemical substance and significant new uses subject to reporting. (1) The chemical substances identified as 1H,4H,14H,17H-2,16:3,15-dimethano-5H,6H,7H,8H,9H,10H,11H,12H,13H,18H,19H,20H,21H,22H,23H,24H,25H,26H-2,3,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,15,16,17a,18a,19a,20a,21a,22a,23a,24a,25a,26a-tetracosaazabispentaleno[1″′,6″′:5″,6″,7″]cycloocta[1″,2″,3″:3′,4′]pentaleno[1′,6′:5,6,7]cycloocta[1,2,3-gh:1′,2′,3′-g′h′]cycloocta[1,2,3-cd:5,6,7-c′d′]dipentalene-1,4,6,8,10,12,14,17,19,21,23,25-dodecone, dodecahydro-, stereoisomer; 2,18:3,17-dimethano-2,3,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,14a,15a,17,18,19a,20a,21a,22a,23a,24a,25a,26a,27a,28a,29a,30a-octacosaazabispentaleno[1″″′,6″″′:5″″, 6″″,7″″]cycloocta[1″″,2″″,3″″:3″′,4″′]pentaleno[1″′,6″′:5″,6″,7″]cycloocta[1″,2″,3″:3′,4′]pentaleno[1′,6′:5,6,7]cycloocta[1,2,3-cd:1′,2′,3′-gh]pentalene-1,4,6,8,10,12,14,16,19,21,23,25,27,29-tetradecone, tetradecahydro-, stereoisomer; 2,20:3,19-dimethano-2,3,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,14a,15a,16a,17a,19,20,21a,22a,23a,24a,25a,26a,27a,28a,29a,30a,31a,32a,33a,34a-dotriacontaazabispentaleno[1″″′,6″″′:5″″,6″″,7″″]cycloocta[1″″,2″″,3″″:3″′,4″′]pentaleno[1″′,6″′:5″,6″,7″]cycloocta[1″,2″,3″:3′,4′]pentaleno
( printed page 69710)
[1′,6′:5,6,7]cycloocta[1,2,3-gh:1′,2′,3′-g′h′]cycloocta[1,2,3-cd:5,6,7-c′d′]dipentalene-1,4,6,8,10,12,14,16,18,21,23,25,27,29,31,33-hexadecone, hexadecahydro-, stereoisomer (PMN P-22-158; CASRNs 283175-97-3; 259886-50-5; 259886-51-6) are subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substances after they have been incorporated into a polymer matrix, or when incorporated into a consumer product at or below 1.7% by weight (calculated by the weight of all three substances combined) and packaged as a consumer product.
(2) The significant new uses are:
(i)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(3)(iii), and (g)(5). Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(ii)
Industrial, commercial, and consumer activities.
It is a significant new use to process for use or use the substances in a consumer product unless the concentration of the substances combined does not exceed 1.7% by weight in the consumer product.
(iii)
Release to water.
Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4) where N = 18.
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (c), (f) through (i), and (k) are applicable to manufacturers, importers, and processors of these substances.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as mixed metal oxide (PMNs P-22-187 and P-24-88; Accession No. 303027) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been entrained in cured coating.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1), (a)(3) through (6), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health (NIOSH) assigned protection factor (APF) of at least 10.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (f), (g)(1) and (5). For purposes of § 721.72(g)(1), this substance may cause: specific target organ toxicity and carcinogenicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
It is a significant new use to manufacture, process, or use the substance in a solid form other than when using dust controls with a capture and control efficiency of >97%.
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (j) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
Rosin, fumarated, polymer with adipic acid and glycerol.
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified as rosin, fumarated, polymer with adipic acid and glycerol (PMN P-23-96; CASRN 2888640-13-7) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1) and (3) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For purposes of § 721.72(g)(1), this substance may cause: eye irritation and skin sensitization. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(o).
(iv)
Release to water.
Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4) where N = 330.
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i), and (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
Derivatives of fats and oils, plant based, polycyclic acids functionalized, aromatic acids, polyester with diols and triols (generic).
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as derivatives of fats and oils, plant based, polycyclic acids functionalized, aromatic acids, polyester with diols and triols (PMN P-23-99) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely reacted or cured.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1), (a)(3) through (6), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health
( printed page 69711)
(NIOSH) assigned protection factor (APF) of at least 10.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For purposes of § 721.72(g)(1), this substance may cause: skin irritation, eye irritation, skin sensitization, reproductive toxicity, and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(o). It is a significant new use to use the substance in spray applications.
(iv)
Release to water.
Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N = 21. For purposes of 721.91(a)(7), the control technology is primary and secondary wastewater treatment as defined in 40 CFR part 133 and the percentage removal of the substance resulting from use of the specified control technology is 90%.
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i), and (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified as multi-walled carbon nanotubes (PMN P-23-105) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely entrained or incorporated into an article.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1), (a)(3) through (6), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health (NIOSH) assigned protection factor (APF) of at least 1,000.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For purposes of § 721.72(g)(1), this substance may cause: eye irritation, skin sensitization, respiratory sensitization, specific target organ toxicity, reproductive toxicity, genetic toxicity, and carcinogenicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(f), (k), (o), and (t). It is a significant new use to manufacture, process, or use the substance in solid form unless using engineering controls with a minimum efficiency of 95% capture and 99% control. Engineering controls are not needed when the substance is in liquid solution or dispersion. It is a significant new use to manufacture, process, or use the substance unless the confidential residual listed in the Order is present at the confidential limit listed in the Order or less by weight.
(iv)
Release to water.
Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1).
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i), and (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as polysubstitutedcarbocycle, polyhydroxy, polyalkyl (PMN P-23-156) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1), (a)(3) through (6), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health (NIOSH) assigned protection factor (APF) of at least 50, or 1,000 if spray applied.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For purposes of § 721.72(g)(1), this substance may cause: respiratory sensitization, skin sensitization, and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(f). It is a significant new use to process for use or use the substance in a consumer product where the concentration of the substance is equal to or exceeds the confidential percentage in formulation listed in the Order.
(iv)
Release to water.
Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4) where N = 19.
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i), and (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
Cashew, nutshell liq., polymer with epichlorohydrin and glycol (generic).
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as cashew, nutshell liq., polymer with epichlorohydrin and glycol (PMN P-24-45) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after
( printed page 69712)
they have been completely reacted or cured.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1), (a)(3) through (6), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health (NIOSH) assigned protection factor (APF) of at least 50.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), and (5). For purposes of § 721.72(g)(1), this substance may cause: skin irritation, eye irritation, reproductive toxicity, and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(o). It is a significant new use to spray apply the substance.
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
Fatty acids, reaction products with alkene polyamine (generic).
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as fatty acids, reaction products with alkene polyamine (PMN P-24-54) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1) and (3) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For purposes of § 721.72(g)(1), this substance may cause: eye corrosion, skin corrosion, skin sensitization, and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(g) and (o). It is a significant new use to manufacture, process, or use the substance in any manner that results in inhalation exposure to the substance.
(iv)
Release to water.
Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1).
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i), and (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
Fatty acids, reaction products with alkene polyamine (generic).
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as fatty acids, reaction products with alkene polyamine (PMN P-24-55) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1) and (3) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For purposes of § 721.72(g)(1), this substance may cause: eye corrosion, skin corrosion, skin sensitization, and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(g) and (o). It is a significant new use to manufacture, process, or use the substance in any manner that results in inhalation exposure to the substance.
(iv)
Release to water.
Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1).
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i), and (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
Fatty acids, reaction products with alkene polyamine (generic).
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as fatty acids, reaction products with alkene polyamine (PMN P-24-56) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1) and (3) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For purposes of § 721.72(g)(1), this substance may cause: eye corrosion, skin corrosion, skin sensitization, and specific target organ toxicity. Alternative hazard and warning
( printed page 69713)
statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(g) and (o). It is a significant new use to manufacture, process, or use the substance in any manner that results in inhalation exposure to the substance.
(iv)
Release to water.
Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1).
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i), and (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
Functionalized fatty acids, reaction products with alkene polyamines (generic).
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as functionalized fatty acids, reaction products with alkene polyamines (PMN P-24-58) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1) and (3) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For purposes of § 721.72(g)(1), this substance may cause: acute toxicity, serious eye damage, skin corrosion, skin sensitization, and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(g) and (o). It is a significant new use to manufacture, process, or use the substance in any manner that results in inhalation exposure to the substance.
(iv)
Release to water.
Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1).
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i) and (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
Functionalized fatty acids, reaction products with alkene polyamines (generic).
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as functionalized fatty acids, reaction products with alkene polyamines (PMN P-24-59) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1) and (3) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For purposes of § 721.72(g)(1), this substance may cause: acute toxicity, serious eye damage, skin corrosion, skin sensitization, and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(g) and (o). It is a significant new use to manufacture, process, or use the substance in any manner that results in inhalation exposure to the substance.
(iv)
Release to water.
Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1).
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i) and (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
Substituted heterocyclic onium compound, salt with fluoropolysubstitutedalkyl substitutedtricycloalkane carboxylate (1:1), polymer with 4-ethenyl-2-methoxylphenol and fluorosubstitutedaromaticalkyl 2-methyl-2-propenoate, di-Me 2,2′-(1,2-diazenediyl)bis[2-methylpropanoate]-initiated (generic).
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as substitutedheterocyclic onium compound, salt with fluoropolysubstitutedalkyl substitutedtricycloalkane carboxylate (1:1), polymer with 4-ethenyl-2-methoxylphenol and fluorosubstitutedaromaticalkyl 2-methyl-2-propenoate, di-Me 2,2′-(1,2-diazenediyl)bis[2-methylpropanoate]-initiated (PMN P-24-98) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely reacted or adhered (during photolithographic processes) onto a semiconductor wafer surface or similar manufactured article used in the production of semiconductor technologies.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1), (a)(2)(i) and (iii), (a)(3), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (f), (g)(1), (g)(2)(i) through (iii) and (g)(2)(v), (g)(3)(i) and (ii), and (g)(5). For purposes of § 721.72(e), the concentration is set at 1.0% by weight or volume. For purposes of § 721.72(g)(1), this substance may cause: acute toxicity, skin irritation, serious eye damage, skin sensitization, genetic
( printed page 69714)
toxicity, and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(f), (k), and (t). It is a significant new use to import the substance other than in solution unless in sealed containers weighing 5 kilograms or less. It is a significant new use to process the substance in any way that generates vapor, dust, mist, or aerosol in a non-enclosed process. It is a significant new use to manufacture the substance longer than 9 months.
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
Dibenzothiophenium, 5-phenyl-, salt with fluorohetero substituted alkyl hetero substituted halo substituted aromatichydrocarboncarboxylate (1:1), polymer with 3-ethenylphenol and fluorocarbomonocyclealkyl 2-methyl-2-propenoate (generic).
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as dibenzothiophenium, 5-phenyl-, salt with fluoroheterosubstituted alkyl hetero substituted halo substituted aromatichydrocarboncarboxylate (1:1), polymer with 3- ethenylphenol and fluorocarbomonocyclealkyl 2-methyl-2-propenoate (PMN P-25-60) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely reacted or adhered (during photolithographic processes) onto a semiconductor wafer surface or similar manufactured article used in the production of semiconductor technologies.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1), (a)(2)(i) and (iii), (a)(3), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (f), (g)(1), (g)(2)(i) through (iii) and (g)(2)(v), (g)(3)(i) and (ii), and (g)(5). For purposes of § 721.72(e), the concentration is set at 1.0% by weight or volume. For purposes of § 721.72(g)(1), this substance may cause: acute toxicity, skin irritation, serious eye damage, skin sensitization, genetic toxicity, and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(f), (k), and (t). It is a significant new use to import the substance other than in solution unless in sealed containers weighing 5 kilograms or less. It is a significant new use to process the substance in any way that generates vapor, dust, mist, or aerosol in a non-enclosed process. It is a significant new use to manufacture the substance longer than 9 months.
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
Dibenzothiophenium, 5-phenyl-, salt with fluoroheterosubstitutedalkyl hetero substituted halo substituted aromatichydrocarboncarboxylate (1:1), polymer with 3-ethenylphenol and alkylcycloalkyl 2-methyl-2-propenoate (generic).
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as dibenzothiophenium, 5-phenyl-, salt with fluoroheterosubstitutedalkyl hetero substituted halo substituted aromatichydrocarboncarboxylate (1:1), polymer with 3- ethenylphenol and alkylcycloalkyl 2-methyl-2-propenoate (PMN P-25-64) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely reacted or adhered (during photolithographic processes) onto a semiconductor wafer surface or similar manufactured article used in the production of semiconductor technologies.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1), (a)(2)(i) and (iii), (a)(3), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (f), (g)(1), (g)(2)(i) through (iii) and (g)(2)(v), (g)(3)(i) and (ii), and (g)(5). For purposes of § 721.72(e), the concentration is set at 1.0% by weight or volume. For purposes of § 721.72(g)(1), this substance may cause: acute toxicity, skin irritation, serious eye damage, skin sensitization, genetic toxicity, and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(f), (k), and (t). It is a significant new use to import the substance other than in solution unless in sealed containers weighing 5 kilograms or less. It is a significant new use to process the substance in any way that generates vapor, dust, mist, or aerosol in a non-enclosed process. It is a significant new use to manufacture the substance longer than 9 months.
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified
( printed page 69715)
generically as lithium dihalo (oxalato)borate(1-) (PMN P-24-109) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been sealed in a battery.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1), (a)(3) through (6), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health (NIOSH) assigned protection factor (APF) of at least 10.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For purposes of § 721.72(g)(1), this substance may cause: acute toxicity, skin irritation, skin sensitization, serious eye damage, reproductive toxicity, and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(o).
(iv)
Release to water.
Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N=1.
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i) and (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
Carbamodithioic acid, N,N-bis(phenylmethyl)-, compd. with 2,2′-dithiobis[ethanamine] (2:1).
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified as carbamodithioic acid, N,N-bis(phenylmethyl)-, compd. with 2,2′-dithiobis[ethanamine] (2:1) (PMN P-24-112; CAS No. 239446-62-9) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance when completely reacted or cured.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1), (a)(3) through (6), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health (NIOSH) assigned protection factor (APF) of at least 10.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For purposes of § 721.72(g)(1), this substance may cause: acute toxicity, skin sensitization, reproductive toxicity, and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(o). It is a significant new use to manufacture the substance other than by import in a pellet form into the United States (
i.e.,
no domestic manufacture).
(iv)
Release to water.
Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1).
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i) (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as benzene, [alkyl [polycycloalkyl]-yl] polyfluoro-alkyl- (PMN P-24-146) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance when sealed inside a display.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1) and (3) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), and (5). For purposes of § 721.72(g)(1), this substance may cause: specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(k). It is a significant new use to manufacture, process, or use the substance other than in a liquid solution.
(iv)
Release to water.
Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1).
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i) and (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as substituted polyphenyl, alkyl-fluoro-alky (PMN P-24-148) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into an article.
(2) The significant new uses are:
( printed page 69716)
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1) and (3) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), and (g)(1) and (5). For purposes of § 721.72(g)(1), this substance may cause: reproductive toxicity and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(k) and (o). It is a significant new use to manufacture, process, or use the substance in any manner that generates a vapor, mist, dust, or aerosol containing the substance.
(iv)
Disposal.
It is a significant new use to dispose of the substance, or waste streams containing the substance, by incineration other than by hazardous waste incineration in compliance with RCRA subtitle C, incineration above 1,000 degrees C for at least two seconds.
(v)
Release to water.
Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1).
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as substituted polyphenyl, alkyl-polyfluoro-alkyl (PMN P-24-149) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into an article.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1) and (3) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), and (5). For purposes of § 721.72(g)(1), this substance may cause: reproductive toxicity and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(k) and (o). It is a significant new use to manufacture, process, or use the substance in any manner that generates a vapor, mist, dust, or aerosol containing the substance.
(iv)
Disposal.
It is a significant new use to dispose of the substance, or waste streams containing the substance, by incineration other than by hazardous waste incineration in compliance with RCRA subtitle C, incineration above 1,000 degrees C for at least two seconds.
(v)
Release to water.
Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1).
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
(a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified generically as substituted polyphenyl, alkyl-alkyl-polyfluoro- (PMN P-24-150) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into an article.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1) and (3) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), and (5). For purposes of § 721.72(g)(1), this substance may cause: reproductive toxicity and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(k) and (o). It is a significant new use to manufacture, process, or use the substance in any manner that generates a vapor, mist, dust, or aerosol containing the substance.
(iv)
Disposal.
It is a significant new use to dispose of the substance, or waste streams containing the substance, by incineration other than by hazardous waste incineration in compliance with RCRA subtitle C, incineration above 1,000 degrees C for at least two seconds.
(v)
Release to water.
Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1).
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as substituted polyphenyl, alkyl-alkyl-fluoro- (PMN P-24-151) is subject to reporting under this section
( printed page 69717)
for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into an article.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1) and (3) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), and (5). For purposes of § 721.72(g)(1), this substance may cause: reproductive toxicity and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(k) and (o). It is a significant new use to manufacture, process, or use the substance in any manner that generates a vapor, mist, dust, or aerosol containing the substance.
(iv)
Disposal.
It is a significant new use to dispose of the substance, or waste streams containing the substance, by incineration other than by hazardous waste incineration in compliance with RCRA subtitle C, incineration above 1,000 degrees C for at least two seconds.
(v)
Release to water.
Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1).
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as phenyl carboxylic acid, alkylcycloalkyl, phenylalkanediyl ester (PMN P-24-152) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into an article.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1) and (3) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), and (5). For purposes of § 721.72(g)(1), this substance may cause: specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(k) and (o). It is a significant new use to manufacture, process, or use the substance in any manner that generates a vapor, mist, dust, or aerosol containing the substance.
(iv)
Disposal.
It is a significant new use to dispose of the substance, or waste streams containing the substance, by hazardous waste landfill other than at a facility that is in compliance with RCRA Subtitle C.
(v)
Release to water.
Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1).
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as fluoro substituted polyphenyl alkyl (PMN P-24-153) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into an article.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1) and (3) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), and (5). For purposes of § 721.72(g)(1), this substance may cause: reproductive toxicity and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(k) and (o). It is a significant new use to manufacture, process, or use the substance in any manner that generates a vapor, mist, dust, or aerosol containing the substance.
(iv)
Disposal.
It is a significant new use to dispose of the substance, or waste streams containing the substance, by incineration unless hazardous waste incineration in compliance with RCRA Subtitle C, incineration above 1,000 degrees C for at least two seconds is used.
(v)
Release to water.
Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1).
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as polyphenyl, ethoxy-polyfluoro-alkyl- (PMN P-24-154) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into an article.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1) and (3) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For purposes of § 721.72(g)(1), this substance may cause: specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(k) and (o). It is a significant new use to manufacture, process, or use the substance in any manner that generates a vapor, mist, dust, or aerosol containing the substance.
(iv)
Disposal.
It is a significant new use to dispose of the substance, or waste streams containing the substance, by incineration unless hazardous waste incineration in compliance with RCRA Subtitle C, incineration above 1,000 degrees C for at least two seconds is used.
(v)
Release to water.
Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1).
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
Transition metal polykis (heteroatom substituted carbomonocycle), hydroxy- oxo- (generic).
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as transition metal polykis (heteroatom substituted carbomonocycle), hydroxy- oxo- (PMN P-24-163) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into an article.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1), (3) through (6), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health (NIOSH) assigned protection factor (APF) of at least 1000 when the proportion of the substance with a particle size less than 10 microns is >0.1% (by weight). When the proportion of the substance with a particle size less than 10 microns is ≤0.1% (by weight), the worker respirator requirement does not apply.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), and (5). For purposes of § 721.72(g)(1), this substance may cause: specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(k).
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as heteromonocyclealkanol, homopolymer, monoalkyl ether (PMN P-25-58) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1) and (3) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For purposes of § 721.72(g)(1), this substance may cause: skin irritation and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(k). It is a significant new use to manufacture, process for use or use the substance in any manner that results in inhalation exposure to the substance.
(iv)
Disposal.
Requirements as specified in § 721.85(a)(1) through (3), (b)(1) through (3), and (c)(1) through (3). For purposes of § 721.85(a)(2), (b)(2), and (c)(2), the landfill must be a hazardous waste landfill facility that is in compliance with subtitles C and D of the Resource Conservation and Recovery Act (RCRA).
(v)
Release to water.
Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N = 140. For purposes of 721.91(a)(7), the control technology is primary and secondary wastewater treatment as defined in 40 CFR part 133 and the percentage removal of the substance resulting from use of the specified control technology is 50%.
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
( printed page 69719)
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (k) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
Sulfonium, bis(dihalo carbomonocycle)carbomonocycle-. salt with dihalo-sulfoalkyl [(alkenylcarbomonocycle)substituted] trisubstituted benzoate, polymer with alkenylcarbomonocycle and alkylcarbomonocycle alkyl alkenoate (generic).
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as sulfonium, bis(dihalo carbomonocycle)carbomonocycle-. salt with dihalo-sulfoalkyl [(alkenylcarbomonocycle)substituted] trisubstituted benzoate, polymer with alkenylcarbomonocycle and alkylcarbomonocycle alkyl alkenoate (PMN P-25-66; Accession No. 303323) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely reacted or adhered (during photolithographic processes) onto a semiconductor wafer surface or similar manufactured article used in the production of semiconductor technologies.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1), (a)(2)(i) and (iii), (a)(3), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (f), (g)(1), (g)(2)(i) through (iii) and (g)(2)(v), (g)(3)(i) and (ii), and (g)(5). For purposes of § 721.72(e), the concentration is set at 1.0% by weight or volume. For purposes of § 721.72(g)(1), this substance may cause: acute toxicity, skin irritation, serious eye damage, skin sensitization, genetic toxicity, and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(f), (k), and (t). It is a significant new use to import the substance other than in solution unless in sealed containers weighing 5 kilograms or less. It is a significant new use to process the substance in any way that generates vapor, dust, mist, or aerosol in a non-enclosed process. It is a significant new use to manufacture the substance longer than 9 months.
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
Sulfonium, bis(dihalo carbomonocycle)(halo carbomonocycle)-, salt with dihalo-sulfoalkyl [(alkenylcarbomonocycle)substituted] trisubstituted benzoate, polymer with alkenylcarbomonocycle and alkylcarbomonocycle alkyl alkenoate (generic).
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as sulfonium, bis(dihalo carbomonocycle)(halocarbomonocycle)-, salt with dihalo-sulfoalkyl [(alkenylcarbomonocycle)substituted] trisubstituted benzoate, polymer with alkenylcarbomonocycle and alkylcarbomonocycle alkyl alkenoate (PMN P-25-70) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely reacted or adhered (during photolithographic processes) onto a semiconductor wafer surface or similar manufactured article used in the production of semiconductor technologies.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1), (a)(2)(i) and (iii), (a)(3), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (f), (g)(1), (g)(2)(i) through (iii) and (g)(2)(v), (g)(3)(i) and (ii), and (g)(5). For purposes of § 721.72(e), the concentration is set at 1.0% by weight or volume. For purposes of § 721.72(g)(1), this substance may cause: acute toxicity, skin irritation, serious eye damage, skin sensitization, genetic toxicity, and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(f), (k), and (t). It is a significant new use to import the substance other than in solution unless in sealed containers weighing 5 kilograms or less. It is a significant new use to process the substance in any way that generates vapor, dust, mist, or aerosol in a non-enclosed process. It is a significant new use to manufacture the substance longer than 9 months.
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
Sulfonium, bis(dihalo carbomonocycle)(halocarbomonocycle)-, salt with trihalobenzoate (generic).
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as sulfonium, bis(dihalo carbomonocycle)(halocarbomonocycle)-, salt with trihalobenzoate (PMN P-25-71) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely reacted or adhered (during photolithographic processes) onto a semiconductor wafer surface or similar manufactured article used in the production of semiconductor technologies.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1), (a)(2)(i) and (iii), (a)(3), and (c). When determining which persons are reasonably likely to be
( printed page 69720)
exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (f), (g)(1), (g)(2)(i) through (iii) and (g)(2)(v), (g)(3)(i) and (ii), and (g)(5). For purposes of § 721.72(e), the concentration is set at 1.0% by weight or volume. For purposes of § 721.72(g)(1), this substance may cause: acute toxicity, skin irritation, serious eye damage, skin sensitization, genetic toxicity, and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(f), (k), and (t). It is a significant new use to import the substance other than in solution unless in sealed containers weighing 5 kilograms or less. It is a significant new use to process the substance in any way that generates vapor, dust, mist, or aerosol in a non-enclosed process. It is a significant new use to manufacture the substance longer than 9 months.
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
Aromatic sulfonium tricyclo salt with carbopolycycloalkyl ester polysubstitutedarylhetero-acid (generic).
(a)
Chemical substance and significant new uses subject to reporting.
(1) The chemical substance identified generically as aromatic sulfonium tricyclo salt with carbopolycycloalkyl ester polysubstitutedarylhetero-acid (PMN P-25-97; Accession No. 303607) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely reacted or adhered (during photolithographic processes) onto a semiconductor wafer surface or similar manufactured article used in the production of semiconductor technologies.
(2) The significant new uses are:
(i)
Protection in the workplace.
Requirements as specified in § 721.63(a)(1), (a)(2)(i) and (iii), (a)(3), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
e.g.,
enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
e.g.,
workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii)
Hazard communication.
Requirements as specified in § 721.72(a) through (f), (g)(1), (g)(2)(i) through (iii) and (g)(2)(v), (g)(3)(i) and (ii), and (g)(5). For purposes of § 721.72(e), the concentration is set at 1.0% by weight or volume. For purposes of § 721.72(g)(1), this substance may cause: acute toxicity, skin irritation, serious eye damage, skin sensitization, genetic toxicity, and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii)
Industrial, commercial, and consumer activities.
Requirements as specified in § 721.80(f), (k), and (t). It is a significant new use to import the substance other than in solution unless in sealed containers weighing 5 kilograms or less. It is a significant new use to process the substance in any way that generates vapor, dust, mist, or aerosol in a non-enclosed process. It is a significant new use to manufacture the substance longer than 18 months.
(b)
Specific requirements.
The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1)
Recordkeeping.
Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance.
(2)
Limitation or revocation of certain notification requirements.
The provisions of § 721.185 apply to this section.
Use this for formal legal and research references to the published document.
91 FR 69704
Web Citation
Suggested Web Citation
Use this when citing the archival web version of the document.
“Significant New Use Rules on Certain Chemical Substances (25-3.5e),” thefederalregister.org (November 5, 2026), https://thefederalregister.org/documents/2026-22576/significant-new-use-rules-on-certain-chemical-substances-25-3-5e.
www.regulations.gov
www.epa.gov/dockets
15 U.S.C. 2604(a)(2)
19 CFR 12.118