80_FR_29202 80 FR 29105 - Microbiome Research

80 FR 29105 - Microbiome Research

OFFICE OF SCIENCE AND TECHNOLOGY POLICY

Federal Register Volume 80, Issue 97 (May 20, 2015)

Page Range29105-29106
FR Document2015-12191

Advanced sequencing technologies have illuminated vast networks of microorganisms that drive essential functions in all environments on Earth. The study of these communities of microorganisms, or microbiomes, is nascent, and the potential of microbiome research has only begun to be tapped. Primary to achieving this potential is a functional understanding of microbiomes, which would be greatly advanced by addressing fundamental questions common to all fields of microbiome research; developing platform technologies useful to all fields; and identifying gaps in training or fields of research that should be addressed. The Office of Science and Technology Policy (OSTP) is interested in developing an effort to unify and focus microbiome research across sectors. The views of stakeholders--academic and industry researchers, private companies, and charitable foundations--are important to inform an understanding of current and future needs in diverse fields.

Federal Register, Volume 80 Issue 97 (Wednesday, May 20, 2015)
[Federal Register Volume 80, Number 97 (Wednesday, May 20, 2015)]
[Notices]
[Pages 29105-29106]
From the Federal Register Online  [www.thefederalregister.org]
[FR Doc No: 2015-12191]


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OFFICE OF SCIENCE AND TECHNOLOGY POLICY


Microbiome Research

ACTION: Notice of Request for Information

-----------------------------------------------------------------------

SUMMARY: Advanced sequencing technologies have illuminated vast 
networks of microorganisms that drive essential functions in all 
environments on Earth. The study of these communities of 
microorganisms, or microbiomes, is nascent, and the potential of 
microbiome research has only begun to be tapped. Primary to achieving 
this potential is a functional understanding of microbiomes, which 
would be greatly advanced by addressing fundamental questions common to 
all fields of microbiome research; developing platform technologies 
useful to all fields; and identifying gaps in training or fields of 
research that should be addressed. The Office of Science and Technology 
Policy (OSTP) is interested in developing an effort to unify and focus 
microbiome research across sectors. The views of stakeholders--academic 
and industry researchers, private companies, and charitable 
foundations--are important to inform an understanding of current and 
future needs in diverse fields.

DATES: Responses must be received by June 15, 2015, to be considered.

ADDRESSES: You may submit comments by any of the following methods:
     Email: [email protected]. Include [Microbiome 
RFI] in the subject line of the message.

[[Page 29106]]

     Fax: (202) 456-6027, Attn: Elizabeth Stulberg.
     Mail: Attn: Elizabeth Stulberg, Office of Science and 
Technology Policy, Eisenhower Executive Office Building, 1650 
Pennsylvania Ave., NW., Washington, DC 20504.
    Instructions: Electronic responses must be provided as attachments 
to an email. It is recommended that attachments with file sizes 
exceeding 25MB be compressed (i.e., zipped) to ensure message delivery. 
Please identify your answers by responding to a specific question or 
topic if possible. Respondents may answer as many or as few questions 
as they wish. Comments of up to two pages or fewer (1,000 words) are 
requested; longer responses will not be considered. Any information 
obtained as a result of this RFI is intended to be used by the 
Government on a non-attribution basis for planning and strategy 
development. OSTP will not respond to individual submissions. A 
response to this RFI will not be viewed as a binding commitment to 
develop or pursue the project or ideas discussed. OSTP will not pay for 
information provided under this RFI. This RFI is not accepting 
applications for financial assistance or financial incentives. OSTP 
requests that no proprietary information, copyrighted information, or 
personally identifiable information be submitted in response to this 
RFI.

FOR FURTHER INFORMATION CONTACT: Elizabeth Stulberg at 
[email protected], (202) 456-4444.

SUPPLEMENTARY INFORMATION: The purpose of this RFI is to solicit 
feedback from industry, academia, research laboratories, and other 
stakeholder groups on both the overarching questions that unite all 
microbiome research and the tools, technologies, and training that are 
needed to answer these questions. OSTP is specifically interested in 
information that corresponds to the mission statements of multiple 
Federal agencies, private sector interests, and current White House 
Policy Initiatives. In particular, respondents may wish to address the 
following topics:
     What are the most pressing, fundamental questions in 
microbiome research, common to most or all fields?
     Over the next ten years, what are the most important 
research gaps that must be addressed to advance this field?
     What tools, platform technologies, or technological 
advances would propel microbiome research from correlative to 
predictive?
     What crucial types of scientific and technical training 
will be needed to take advantage of harnessing the microbiome's 
potential?
     What fields of microbiome research are currently 
underfunded or underrepresented?
     What specific steps could be taken by the federal 
government, research institutes, universities, and philanthropies to 
encourage multi-disciplinary microbiome research?
     Is there any additional information, not requested above, 
that you believe OSTP should consider in identifying crucial areas of 
microbiome research?

Ted Wackler,
Deputy Chief of Staff and Assistant Director.
[FR Doc. 2015-12191 Filed 5-19-15; 8:45 am]
BILLING CODE 3270-F5-P



                                                                               Federal Register / Vol. 80, No. 97 / Wednesday, May 20, 2015 / Notices                                                   29105

                                                  significantly increase cumulative                       www.prc.gov. Those who cannot submit                  interests of the general public (Public
                                                  occupational radiation exposure.                        comments electronically should contact                Representative) in this docket.
                                                  Therefore, the requirements of 10 CFR                   the person identified in the FOR FURTHER
                                                                                                                                                                III. Ordering Paragraphs
                                                  51.22(c)(9)(iii) are met.                               INFORMATION CONTACT section by
                                                                                                          telephone for advice on filing                           It is ordered:
                                                  Conclusion                                                                                                       1. The Commission reopens Docket
                                                                                                          alternatives.
                                                     Based on the above, the NRC staff                                                                          No. CP2015–9 for consideration of
                                                                                                          FOR FURTHER INFORMATION CONTACT:                      matters raised by the Postal Service’s
                                                  concludes that the proposed exemption
                                                                                                          David A. Trissell, General Counsel, at                Notice.
                                                  meets the eligibility criteria for the
                                                                                                          202–789–6820.                                            2. Pursuant to 39 U.S.C. 505, the
                                                  categorical exclusion set forth in 10 CFR
                                                  51.22(c)(9). Therefore, in accordance                   SUPPLEMENTARY INFORMATION:                            Commission appoints Lyudmila Y.
                                                  with 10 CFR 51.22(b), no environmental                  Table of Contents                                     Bzhilyanskaya to serve as an officer of
                                                  impact statement or environmental                                                                             the Commission (Public Representative)
                                                                                                          I. Introduction                                       to represent the interests of the general
                                                  assessment need be prepared in
                                                                                                          II. Notice of Filing                                  public in this proceeding.
                                                  connection with the NRC’s proposed                      III. Ordering Paragraphs
                                                  issuance of this exemption.                                                                                      3. Comments are due no later than
                                                                                                          I. Introduction                                       May 21, 2015.
                                                  IV. Conclusions                                                                                                  4. The Secretary shall arrange for
                                                                                                             On May 13, 2015, the Postal Service                publication of this order in the Federal
                                                     Accordingly, the Commission has                      filed notice that it has agreed to a
                                                  determined that, pursuant to 10 CFR                                                                           Register.
                                                                                                          Modification to the existing Global
                                                  50.12, the exemption is authorized by                                                                           By the Commission.
                                                                                                          Expedited Package Services 3 negotiated
                                                  law, will not present an undue risk to                  service agreement approved in this                    Shoshana M. Grove,
                                                  the public health and safety, and is                    docket.1 In support of its Notice, the                Secretary.
                                                  consistent with the common defense                      Postal Service includes a redacted copy               [FR Doc. 2015–12119 Filed 5–19–15; 8:45 am]
                                                  and security. Also, special                             of the Modification and a certification of            BILLING CODE 7710–FW–P
                                                  circumstances pursuant to 10 CFR                        compliance with 39 U.S.C. 3633(a), as
                                                  50.12(a)(2)(ii) are present. Therefore, the             required by 39 CFR 3015.5. Notice,
                                                  Commission hereby grants Dominion                       Attachments 1 and 2.                                  OFFICE OF SCIENCE AND
                                                  Nuclear Connecticut, Inc., an exemption                    The Postal Service also filed the                  TECHNOLOGY POLICY
                                                  from the requirements of 10 CFR 50.46                   unredacted Modification and supporting
                                                  and Appendix K to 10 CFR part 50, to                    financial information under seal. Notice              Microbiome Research
                                                  allow the application of those criteria to,             at 1. The Postal Service seeks to
                                                  and the use of, M5 fuel rod cladding                                                                          ACTION:Notice of Request for
                                                                                                          incorporate by reference the Application
                                                  material at MPS2.                                                                                             Information
                                                                                                          for Non-Public Treatment originally
                                                     This exemption is effective upon                     filed in this docket for the protection of            SUMMARY:   Advanced sequencing
                                                  issuance.                                               information that it has filed under seal.             technologies have illuminated vast
                                                    Dated at Rockville, Maryland, this 12th               Id. at 1–2.                                           networks of microorganisms that drive
                                                  Day of May, 2015.                                          The Modification adds a new                        essential functions in all environments
                                                  For the Nuclear Regulatory Commission                   paragraph to Article 5 addressing the                 on Earth. The study of these
                                                  Louise Lund,                                            use of permit imprints, adds a new                    communities of microorganisms, or
                                                  Acting Director, Division of Operating Reactor          paragraph to Article 5 (text under seal),             microbiomes, is nascent, and the
                                                  Licensing, Office of Nuclear Reactor                    revises the minimum commitment in                     potential of microbiome research has
                                                  Regulation.                                             Article 11, and replaces Annex 2 (price               only begun to be tapped. Primary to
                                                  [FR Doc. 2015–12264 Filed 5–19–15; 8:45 am]             charts). Id. at 1. The Postal Service                 achieving this potential is a functional
                                                  BILLING CODE 7590–01–P                                  intends the rates in the Modification to              understanding of microbiomes, which
                                                                                                          take effect June 1, 2015. Id. at 1. The               would be greatly advanced by
                                                                                                          Postal Service asserts that the                       addressing fundamental questions
                                                  POSTAL REGULATORY COMMISSION                            Modification will not impair the ability              common to all fields of microbiome
                                                  [Docket No. CP2015–9; Order No. 2483]
                                                                                                          of the contract to comply with 39 U.S.C.              research; developing platform
                                                                                                          3633. Id. Attachment 2.                               technologies useful to all fields; and
                                                  New Postal Product                                                                                            identifying gaps in training or fields of
                                                                                                          II. Notice of Filing
                                                                                                                                                                research that should be addressed. The
                                                  AGENCY: Postal Regulatory Commission.                     The Commission invites comments on                  Office of Science and Technology Policy
                                                  ACTION: Notice.                                         whether the changes presented in the                  (OSTP) is interested in developing an
                                                                                                          Postal Service’s Notice are consistent                effort to unify and focus microbiome
                                                  SUMMARY:   The Commission is noticing a                 with the policies of 39 U.S.C. 3632,                  research across sectors. The views of
                                                  recent Postal Service filing concerning a               3633, or 3642, 39 CFR 3015.5, and 39                  stakeholders—academic and industry
                                                  modification to a Global Expedited                      CFR part 3020, subpart B. Comments are                researchers, private companies, and
                                                  Package Services 3 negotiated service                   due no later than May 21, 2015. The                   charitable foundations—are important
                                                  agreement. This notice informs the                      public portions of these filings can be               to inform an understanding of current
                                                  public of the filing, invites public                    accessed via the Commission’s Web site                and future needs in diverse fields.
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                                                  comment, and takes other                                (http://www.prc.gov).                                 DATES: Responses must be received by
                                                  administrative steps.                                     The Commission appoints Lyudmila                    June 15, 2015, to be considered.
                                                  DATES: Comments are due: May 21,                        Y. Bzhilyanskaya to represent the                     ADDRESSES: You may submit comments
                                                  2015.
                                                                                                            1 Notice of the United States Postal Service of
                                                                                                                                                                by any of the following methods:
                                                  ADDRESSES:   Submit comments                            Filing Modification to Global Expedited Package
                                                                                                                                                                   • Email: MicrobiomeRFI@
                                                  electronically via the Commission’s                     Services 3 Negotiated Service Agreement, May 13,      ostp.eop.gov. Include [Microbiome RFI]
                                                  Filing Online system at http://                         2015 (Notice).                                        in the subject line of the message.


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                                                  29106                        Federal Register / Vol. 80, No. 97 / Wednesday, May 20, 2015 / Notices

                                                     • Fax: (202) 456–6027, Attn:                         advantage of harnessing the                             II. Self-Regulatory Organization’s
                                                  Elizabeth Stulberg.                                     microbiome’s potential?                                 Statement of the Purpose of, and
                                                     • Mail: Attn: Elizabeth Stulberg,                      • What fields of microbiome research                  Statutory Basis for, the Proposed Rule
                                                  Office of Science and Technology                        are currently underfunded or                            Change
                                                  Policy, Eisenhower Executive Office                     underrepresented?                                          In its filing with the Commission, the
                                                  Building, 1650 Pennsylvania Ave., NW.,                    • What specific steps could be taken                  self-regulatory organization included
                                                  Washington, DC 20504.                                   by the federal government, research                     statements concerning the purpose of,
                                                     Instructions: Electronic responses                   institutes, universities, and                           and basis for, the proposed rule change
                                                  must be provided as attachments to an                   philanthropies to encourage multi-                      and discussed any comments it received
                                                  email. It is recommended that                           disciplinary microbiome research?                       on the proposed rule change. The text
                                                  attachments with file sizes exceeding                     • Is there any additional information,                of these statements may be examined at
                                                  25MB be compressed (i.e., zipped) to                    not requested above, that you believe                   the places specified in Item IV below.
                                                  ensure message delivery. Please identify                OSTP should consider in identifying                     The self-regulatory organization has
                                                  your answers by responding to a                         crucial areas of microbiome research?                   prepared summaries, set forth in
                                                  specific question or topic if possible.                                                                         sections A, B and C below, of the most
                                                                                                          Ted Wackler,
                                                  Respondents may answer as many or as                                                                            significant aspects of such statements.
                                                  few questions as they wish. Comments                    Deputy Chief of Staff and Assistant Director.
                                                  of up to two pages or fewer (1,000                      [FR Doc. 2015–12191 Filed 5–19–15; 8:45 am]             A. Self-Regulatory Organization’s
                                                  words) are requested; longer responses                  BILLING CODE 3270–F5–P                                  Statement of the Purpose of, and
                                                  will not be considered. Any information                                                                         Statutory Basis for, the Proposed Rule
                                                  obtained as a result of this RFI is                                                                             Change
                                                  intended to be used by the Government                                                                           1. Purpose
                                                  on a non-attribution basis for planning                 SECURITIES AND EXCHANGE
                                                                                                          COMMISSION                                                 The Exchange proposes to amend the
                                                  and strategy development. OSTP will
                                                                                                                                                                  Schedule of Fees to introduce a new
                                                  not respond to individual submissions.
                                                                                                                                                                  ‘‘Retail’’ designation for Priority
                                                  A response to this RFI will not be                      [Release No. 34–74970; File No. SR–ISE–
                                                                                                          2015–14]
                                                                                                                                                                  Customer orders. A ‘‘Priority Customer’’
                                                  viewed as a binding commitment to
                                                                                                                                                                  is a person or entity that is not a broker/
                                                  develop or pursue the project or ideas                                                                          dealer in securities, and does not place
                                                  discussed. OSTP will not pay for                        Self-Regulatory Organizations;
                                                                                                          International Securities Exchange,                      more than 390 orders in listed options
                                                  information provided under this RFI.                                                                            per day on average during a calendar
                                                  This RFI is not accepting applications                  LLC; Notice of Filing and Immediate
                                                                                                          Effectiveness of Proposed Rule                          month for its own beneficial account(s),
                                                  for financial assistance or financial                                                                           as defined in Rule 100(a)(37A). This
                                                  incentives. OSTP requests that no                       Change To Amend the Schedule of
                                                                                                          Fees To Introduce a New ‘‘Retail’’                      market participant type is one of six
                                                  proprietary information, copyrighted                                                                            currently recognized for purposes of
                                                  information, or personally identifiable                 Designation for Priority Customer
                                                                                                          Orders                                                  determining applicable fees and rebates,
                                                  information be submitted in response to                                                                         along with: Market Maker,3 Non-ISE
                                                  this RFI.                                               May 14, 2015.                                           Market Maker,4 Firm Proprietary,5
                                                  FOR FURTHER INFORMATION CONTACT:                           Pursuant to Section 19(b)(1) of the                  Broker-Dealer,6 and Professional
                                                  Elizabeth Stulberg at MicrobiomeRFI@                    Securities Exchange Act of 1934 (the                    Customer.7 The Priority Customer
                                                  ostp.eop.gov, (202) 456–4444.                           ‘‘Act’’),1 and Rule 19b–4 thereunder,2                  designation was adopted by the
                                                  SUPPLEMENTARY INFORMATION: The                          notice is hereby given that on April 29,                Exchange to provide competitive pricing
                                                  purpose of this RFI is to solicit feedback              2015, the International Securities                      and market structure advantages to
                                                  from industry, academia, research                       Exchange, LLC (the ‘‘Exchange’’ or the                  retail investors, and to level the playing
                                                  laboratories, and other stakeholder                     ‘‘ISE’’) filed with the Securities and                  field between retail investors and
                                                  groups on both the overarching                          Exchange Commission the proposed                        market professionals. As such, Priority
                                                  questions that unite all microbiome                     rule change, as described in Items I, II,               Customer orders executed on the
                                                  research and the tools, technologies, and               and III below, which items have been                    Exchange are generally afforded more
                                                  training that are needed to answer these                prepared by the self-regulatory                         favorable fees and rebates than other
                                                  questions. OSTP is specifically                         organization. The Commission is                         market participants, including
                                                  interested in information that                          publishing this notice to solicit                       Professional Customers. The Exchange
                                                  corresponds to the mission statements                   comments on the proposed rule change                    now believes that it is appropriate to
                                                  of multiple Federal agencies, private                   from interested persons.                                introduce a further distinction between
                                                  sector interests, and current White
                                                                                                          I. Self-Regulatory Organization’s
                                                  House Policy Initiatives. In particular,                                                                           3 The term ‘‘Market Makers’’ refers to
                                                                                                          Statement of the Terms of Substance of                  ‘‘Competitive Market Makers’’ and ‘‘Primary Market
                                                  respondents may wish to address the
                                                                                                          the Proposed Rule Change                                Makers’’ collectively. See Rule 100(a)(25).
                                                  following topics:                                                                                                  4 A ‘‘Non-ISE Market Maker’’ is a market maker
                                                     • What are the most pressing,                           The ISE proposes to amend the                        as defined in Section 3(a)(38) of the Securities
                                                  fundamental questions in microbiome                     Schedule of Fees to introduce a new                     Exchange Act of 1934, as amended, registered in the
                                                  research, common to most or all fields?                 ‘‘Retail’’ designation for Priority                     same options class on another options exchange.
                                                     • Over the next ten years, what are                  Customer orders. The text of the                        See Schedule of Fees, Preface.
                                                                                                                                                                     5 A ‘‘Firm Proprietary’’ order is an order
mstockstill on DSK4VPTVN1PROD with NOTICES




                                                  the most important research gaps that                   proposed rule change is available on the                submitted by a member for its own proprietary
                                                  must be addressed to advance this field?                Exchange’s Web site (http://                            account. See Schedule of Fees, Preface.
                                                     • What tools, platform technologies,                 www.ise.com), at the principal office of                   6 A ‘‘Broker-Dealer’’ order is an order submitted

                                                  or technological advances would propel                  the Exchange, and at the Commission’s                   by a member for a broker-dealer account that is not
                                                  microbiome research from correlative to                 Public Reference Room.                                  its own proprietary account. See Schedule of Fees,
                                                                                                                                                                  Preface.
                                                  predictive?                                                                                                        7 A ‘‘Professional Customer’’ is a person or entity
                                                     • What crucial types of scientific and                 1 15   U.S.C. 78s(b)(1).                              that is not a broker/dealer and is not a Priority
                                                  technical training will be needed to take                 2 17   CFR 240.19b–4.                                 Customer. See Schedule of Fees, Preface.



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Document Created: 2018-02-21 10:29:16
Document Modified: 2018-02-21 10:29:16
CategoryRegulatory Information
CollectionFederal Register
sudoc ClassAE 2.7:
GS 4.107:
AE 2.106:
PublisherOffice of the Federal Register, National Archives and Records Administration
SectionNotices
ActionNotice of Request for Information
DatesResponses must be received by June 15, 2015, to be considered.
ContactElizabeth Stulberg at [email protected], (202) 456-4444.
FR Citation80 FR 29105 

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