81 FR 42706 - FIFRA Scientific Advisory Panel; Notice of Public Meeting
ENVIRONMENTAL PROTECTION AGENCY Federal Register Volume 81, Issue 126 (June 30, 2016)
Federal Register Volume 81, Issue 126 (June 30, 2016)
| Page Range | 42706-42708 | |
| FR Document | 2016-15589 |
[Federal Register Volume 81, Number 126 (Thursday, June 30, 2016)] [Notices] [Pages 42706-42708] From the Federal Register Online [www.thefederalregister.org] [FR Doc No: 2016-15589] ----------------------------------------------------------------------- ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OPP-2016-0349; FRL-9948-17] FIFRA Scientific Advisory Panel; Notice of Public Meeting AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. ----------------------------------------------------------------------- SUMMARY: There will be a 2-day meeting of the Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) to consider and review a set of scientific issues being considered by the Environmental Protection Agency regarding the human health and ecological risk assessments for SmartStax PRO (MON 89034 x TC1507 x MON 87411 x DAS-59122-7), a plant-incorporated protectant intended to control corn rootworm through ribonucleic acid (RNA) interference. DATES: The meeting will be held on September 27-28, 2016, from approximately 9:00 a.m. to 5:00 p.m. Comments. The Agency encourages written comments be submitted on or before September 13, 2016, to provide adequate time for the FIFRA SAP to review and consider the comments. The Agency encourages requests for oral comments be submitted on or before September 20, 2016. However, written comments and requests to make oral comments may be submitted until the date of the meeting, but anyone submitting written comments after September 13, 2016, should contact the Designated Federal Official (DFO) listed under FOR FURTHER INFORMATION CONTACT. For additional instructions, see Unit I.C. of the SUPPLEMENTARY INFORMATION. Nominations. Nominations of candidates to serve as ad hoc members of FIFRA SAP for this meeting should be provided on or before August 1, 2016. Webcast. This meeting may be webcast. Please refer to the FIFRA SAP Web site at http://www.epa.gov/sap for information on how to access the meeting webcast. Please note that the webcast is a supplementary public process provided only for convenience. If difficulties arise resulting in webcasting outages, the meeting will continue as planned. Special accommodations. For information on access or services for individuals with disabilities, and to request accommodation of a disability, please contact the DFO listed under FOR FURTHER INFORMATION CONTACT at least 10 days prior to the meeting to give EPA as much time as possible to process your request. ADDRESSES: Meeting: The meeting will be held at the Environmental Protection Agency, Conference Center, Lobby Level, One Potomac Yard (South Bldg.), 2777 S. Crystal Dr., Arlington, VA 22202. Comments: Submit your comments, identified by docket identification (ID) number EPA-HQ-OPP-2016-0349, by one of the following methods:Federal eRulemaking Portal: http://www.regulations.gov. Follow the online instructions for submitting comments. Do not submit electronically any information you consider to be Confidential Business Information (CBI) or other information whose disclosure is restricted by statute. Mail: OPP Docket, Environmental Protection Agency Docket Center (EPA/DC), (28221T), 1200 Pennsylvania Ave. NW., Washington, DC 20460-0001. Hand Delivery: To make special arrangements for hand delivery or [[Page 42707]] delivery of boxed information, please follow the instructions at http://www.epa.gov/dockets/contacts.html. Additional instructions on commenting or visiting the docket, along with more information about dockets generally, is available at http://www.epa.gov/dockets. Nominations, requests to present oral comments, and requests for special accommodations. Submit nominations to serve as ad hoc members of FIFRA SAP, requests for special accommodations, or requests to present oral comments to the DFO listed under FOR FURTHER INFORMATION CONTACT. FOR FURTHER INFORMATION CONTACT: Steven Knott, DFO, Office of Science Coordination and Policy (7201M), Environmental Protection Agency, 1200 Pennsylvania Ave. NW., Washington, DC 20460-0001; telephone number: (202) 564-0103; email address: [email protected]. SUPPLEMENTARY INFORMATION: I. General Information A. Does this action apply to me? This action is directed to the public in general. This action may, however, be of interest to persons who are or may be required to conduct testing of chemical substances under the Federal Food, Drug, and Cosmetic Act (FFDCA) and FIFRA. Since other entities may also be interested, the Agency has not attempted to describe all the specific entities that may be affected by this action. B. What should I consider as I prepare my comments for EPA? 1. Submitting CBI. Do not submit CBI information to EPA through regulations.gov or email. If your comments contain any information that you consider to be CBI or otherwise protected, please contact the DFO listed under FOR FURTHER INFORMATION CONTACT to obtain special instructions before submitting your comments. 2. Tips for preparing your comments. When preparing and submitting your comments, see the commenting tips at http://www.epa.gov/dockets/comments.html. C. How may I participate in this meeting? You may participate in this meeting by following the instructions in this unit. To ensure proper receipt by EPA, it is imperative that you identify docket ID number EPA-HQ-OPP-2016-0349 in the subject line on the first page of your request. 1. Written comments. The Agency encourages written comments be submitted, using the instructions in ADDRESSES and Unit I.B., on or before September 13, 2016, to provide FIFRA SAP the time necessary to consider and review the written comments. Written comments are accepted until the date of the meeting, but anyone submitting written comments after September 13, 2016, should contact the DFO listed under FOR FURTHER INFORMATION CONTACT. Anyone submitting written comments at the meeting should bring 15 copies for distribution to FIFRA SAP by the DFO. 2. Oral comments. The Agency encourages each individual or group wishing to make brief oral comments to FIFRA SAP to submit their request to the DFO listed under FOR FURTHER INFORMATION CONTACT on or before September 20, 2016, in order to be included on the meeting agenda. Requests to present oral comments will be accepted until the date of the meeting and, to the extent that time permits, the Chair of FIFRA SAP may permit the presentation of oral comments at the meeting by interested persons who have not previously requested time. The request should identify the name of the individual making the presentation, the organization (if any) the individual will represent, and any requirements for audiovisual equipment. Oral comments before FIFRA SAP are limited to approximately 5 minutes unless prior arrangements have been made. In addition, each speaker should bring 15 copies of his or her comments and presentation for distribution to FIFRA SAP at the meeting by the DFO. 3. Seating at the meeting. Seating at the meeting will be open and on a first-come basis. 4. Request for nominations to serve as ad hoc members of FIFRA SAP for this meeting. As part of a broader process for developing a pool of candidates for each meeting, FIFRA SAP staff routinely solicits the stakeholder community for nominations of prospective candidates for service as ad hoc members of FIFRA SAP. Any interested person or organization may nominate qualified individuals to be considered as prospective candidates for a specific meeting. Individuals nominated for this meeting should have expertise in one or more of the following areas: Ecological risk assessment, human health risk assessment, entomology, bioinformatics, RNAi technology, biotechnology, plant breeding and genomics, and molecular biology. Nominees should be scientists who have sufficient professional qualifications, including training and experience, to provide expert comments on the scientific issues for this meeting. Nominees should be identified by name, occupation, position, address, email address, and telephone number. Nominations should be provided to the DFO listed under FOR FURTHER INFORMATION CONTACT on or before August 1, 2016. The Agency will consider all nominations of prospective candidates for this meeting that are received on or before that date. However, final selection of ad hoc members for this meeting is a discretionary function of the Agency. The selection of scientists to serve on FIFRA SAP is based on the function of the Panel and the expertise needed to address the Agency's charge to the Panel. No interested scientists shall be ineligible to serve by reason of their membership on any other advisory committee to a federal department or agency, or their employment by a federal department or agency except EPA. Other factors considered during the selection process include availability of the potential Panel member to fully participate in the Panel's reviews, absence of any conflicts of interest or appearance of lack of impartiality, independence with respect to the matters under review, and lack of bias. Although financial conflicts of interest, the appearance of lack of impartiality, lack of independence, and bias may result in disqualification, the absence of such concerns does not assure that a candidate will be selected to serve on the FIFRA SAP. Numerous qualified candidates are identified for each Panel. Therefore, selection decisions involve carefully weighing a number of factors including the candidates' areas of expertise and professional qualifications and achieving an overall balance of different scientific perspectives on the Panel. The Agency anticipates selecting approximately eight ad hoc scientists to have the collective breadth of experience needed to address the Agency's charge for this meeting. FIFRA SAP members are subject to the provisions of 5 CFR part 2634--Executive Branch Financial Disclosure, Qualified Trusts, and Certificates of Divestiture, as supplemented by EPA in 5 CFR part 6401. In anticipation of this requirement, prospective candidates for service on FIFRA SAP will be asked to submit confidential financial information which shall fully disclose, among other financial interests, the candidates' employment, stocks, bonds, and where applicable, sources of research support. EPA will evaluate the candidates' financial disclosure forms to assess whether there are financial conflicts of interest, appearance of a lack of impartiality, or any prior involvement with the development of [[Page 42708]] the documents under consideration (including previous scientific peer review) before the candidate is considered further for service on the FIFRA SAP. Those who are selected from the pool of prospective candidates will be asked to attend the public meetings and to participate in the discussion of key issues and assumptions at these meetings. In addition, they will be asked to review and to help finalize the meeting minutes. The list of FIFRA SAP members participating at this meeting will be posted on the FIFRA SAP Web site at http://www.epa.gov/sap or may be obtained from the OPP Docket at http://www.regulations.gov. II. Background A. Purpose of FIFRA SAP FIFRA SAP serves as the primary scientific peer review mechanism of EPA's Office of Chemical Safety and Pollution Prevention and is structured to provide scientific advice, information and recommendations to the EPA Administrator on pesticides and pesticide- related issues as to the impact of regulatory actions on health and the environment. FIFRA SAP is a federal advisory committee established in 1975 under FIFRA that operates in accordance with requirements of the Federal Advisory Committee Act (5 U.S.C. Appendix). FIFRA SAP is composed of a permanent panel consisting of seven members who are appointed by the EPA Administrator from nominees provided by the National Institutes of Health and the National Science Foundation. FIFRA established a Science Review Board (SRB) consisting of at least 60 scientists who are available to FIFRA SAP on an ad hoc basis to assist in reviews conducted by FIFRA SAP. As a scientific peer review mechanism, FIFRA SAP provides comments, evaluations, and recommendations to improve the effectiveness and quality of analyses made by Agency scientists. Members of the FIFRA SAP are scientists who have sufficient professional qualifications, including training and experience, to provide expert advice and recommendations to the Agency. B. Public Meeting The use of RNA interference (RNAi) gene silencing technology, particularly RNAi for pesticidal purposes to control macroorganism pests, is a relatively recent innovation. Post-transcriptional silencing of gene function is a very rapid process where double- stranded RNA (dsRNA) directs sequence-specific degradation of a RNA. As EPA anticipated receiving pesticide applications based on RNAi technologies and identified the need to better understand the scientific issues concerning the assessment of the risks to human health and the environment that RNAi technologies pose, it convened a January 28, 2014, Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel (FIFRA SAP). This FIFRA SAP provided EPA with scientific advice regarding the framework for assessing RNAi pesticide products. On October 29, 2015, EPA registered MON 87411, a corn plant- incorporated protectant (PIP) for seed increase/breeding purposes only and not for commercial release, with a time limitation of 2 years and a per-season acreage cap of 15,000 acres. In addition to Bacillus thuringiensis (Bt) Cry3Bb1 protein, MON 87411 expresses DvSnf7 dsRNA. Upon consumption by corn rootworm (CRW), the insect's RNAi machinery recognizes DvSnf7 dsRNA, resulting in down-regulation of the targeted DvSnf7 gene and leading to CRW mortality. Earlier this year, EPA received applications from Monsanto Company and Dow AgroSciences, LLC, requesting registration of commercial release RNAi PIPs expressing DvSnf7 dsRNA and known by the name SmartStax PRO. SmartStax PRO also expresses several Bt insecticidal Cry proteins. EPA will present the human health risk assessment conducted for DvSnf7 dsRNA, as expressed in SmartStax PRO, and will consider the fate of ingested dsRNA and the potential for impacts on gene expression and the immune system. The action of a RNA interference construct relies upon some level of sequence homology with the target gene transcript; however, the fidelity of the sequence match may vary in some instances. EPA will discuss the role that bioinformatic analysis may play in understanding and predicting possible off-target effects within the host genome, as well as in predicting nontarget effects as part of the ecological risk assessment. EPA will also present an ecological risk assessment for DvSnf7 dsRNA, as expressed in SmartStax PRO, and will include descriptions of environmental fate and nontarget exposure, data reviewed in support of the risk assessment, risk characterization and description, and uncertainties. The charge to the panel will request expert opinion on completeness of the data set and uncertainties related to the risk conclusions. C. FIFRA SAP Documents and Meeting Minutes EPA's background paper, related supporting materials, charge/ questions to FIFRA SAP, FIFRA SAP composition (i.e., members and ad hoc members for this meeting), and the meeting agenda will be available by approximately late August. In addition, the Agency may provide additional background documents as the materials become available. You may obtain electronic copies of these documents, and certain other related documents that might be available at http://www.regulations.gov and the FIFRA SAP Web site at http://www.epa.gov/sap. FIFRA SAP will prepare meeting minutes summarizing its recommendations to the Agency approximately 90 days after the meeting. The meeting minutes will be posted to the FIFRA SAP Web site or may be obtained from the OPP Docket at http://www.regulations.gov. Authority: 7 U.S.C. 136 et seq.; 21 U.S.C. 301 et seq. Dated: June 23, 2016. Stanley Barone, Acting Director, Office of Science Coordination and Policy. [FR Doc. 2016-15589 Filed 6-29-16; 8:45 am] BILLING CODE 6560-50-P
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description of the ICR is given below, system is inoperative. These reports are DATES: The meeting will be held on
including its estimated burden and cost used by EPA to determine compliance September 27–28, 2016, from
to the public. An Agency may not with these standards. approximately 9:00 a.m. to 5:00 p.m.
conduct or sponsor and a person is not Form Numbers: None. Comments. The Agency encourages
required to respond to a collection of Respondents/Affected Entities: written comments be submitted on or
information unless it displays a Flexible vinyl and urethane coating and before September 13, 2016, to provide
currently valid OMB control number. printing facilities. adequate time for the FIFRA SAP to
DATES: Additional comments may be Respondent’s Obligation to Respond: review and consider the comments. The
submitted on or before August 1, 2016. Mandatory (40 CFR part 60, subpart Agency encourages requests for oral
ADDRESSES: Submit your comments, FFF). comments be submitted on or before
referencing Docket ID Number EPA– Estimated Number of Respondents: 25 September 20, 2016. However, written
HQ–OECA–2012–0657, to: (1) EPA (total). comments and requests to make oral
online using www.regulations.gov (our Frequency of Response: Initially and comments may be submitted until the
preferred method), or by email to semiannually. date of the meeting, but anyone
docket.oeca@epa.gov, or by mail to: EPA Total Estimated Burden: 848 hours submitting written comments after
Docket Center, Environmental (per year). Burden is defined at 5 CFR September 13, 2016, should contact the
Protection Agency, Mail Code 28221T, 1320.3(b). Designated Federal Official (DFO) listed
1200 Pennsylvania Ave. NW., Total Estimated Cost: $320,000 (per under FOR FURTHER INFORMATION
Washington, DC 20460; and (2) OMB via year), which includes $232,000 in both CONTACT. For additional instructions,
email to oira_submission@omb.eop.gov. annualized capital/startup and see Unit I.C. of the SUPPLEMENTARY
operation & maintenance costs. INFORMATION.
Address comments to OMB Desk Officer
Changes in the Estimates: There is an Nominations. Nominations of
for EPA.
EPA’s policy is that all comments adjustment increase in the respondent candidates to serve as ad hoc members
received will be included in the public burden and cost, including total O&M of FIFRA SAP for this meeting should
docket without change, including any cost, in this ICR. This is not due to be provided on or before August 1,
personal information provided, unless program changes; rather, it is due to an 2016.
Webcast. This meeting may be
the comment includes profanity, threats, increase of one additional source being
webcast. Please refer to the FIFRA SAP
information claimed to be Confidential subject to these regulations since the
Web site at http://www.epa.gov/sap for
Business Information (CBI), or other last ICR renewal period. In addition,
information on how to access the
information whose disclosure is this ICR assumes all existing sources
meeting webcast. Please note that the
restricted by statute. will need to re-familiarize themselves
webcast is a supplementary public
FOR FURTHER INFORMATION CONTACT: with the regulation each year. This
process provided only for convenience.
Patrick Yellin, Monitoring, Assistance, change in assumption also contributes
If difficulties arise resulting in
and Media Programs Division, Office of to an increase in the labor hours and
webcasting outages, the meeting will
Compliance, Mail Code 2227A, costs.
continue as planned.
Environmental Protection Agency, 1200 Dated: June 23, 2016. Special accommodations. For
Pennsylvania Ave. NW., Washington, Matthew Leopard, information on access or services for
DC 20460; telephone number: (202) Director, Office of Information Collection. individuals with disabilities, and to
564–2970; fax number: (202) 564–0050; request accommodation of a disability,
[FR Doc. 2016–15567 Filed 6–29–16; 8:45 am]
email address: yellin.patrick@epa.gov. please contact the DFO listed under FOR
BILLING CODE 6560–50–P
SUPPLEMENTARY INFORMATION: FURTHER INFORMATION CONTACT at least
Supporting documents which explain in 10 days prior to the meeting to give EPA
detail the information that the EPA will ENVIRONMENTAL PROTECTION as much time as possible to process
be collecting are available in the public AGENCY your request.
docket for this ICR. The docket can be ADDRESSES:
viewed online at www.regulations.gov Meeting: The meeting will be held at
[EPA–HQ–OPP–2016–0349; FRL–9948–17]
or in person at the EPA Docket Center, the Environmental Protection Agency,
WJC West, Room 3334, 1301 FIFRA Scientific Advisory Panel; Conference Center, Lobby Level, One
Constitution Ave. NW., Washington, Notice of Public Meeting Potomac Yard (South Bldg.), 2777 S.
DC. The telephone number for the Crystal Dr., Arlington, VA 22202.
Docket Center is 202–566–1744. For AGENCY: Environmental Protection Comments: Submit your comments,
additional information about EPA’s Agency (EPA). identified by docket identification (ID)
public docket, visit: http:// ACTION: Notice. number EPA–HQ–OPP–2016–0349, by
www.epa.gov/dockets. one of the following methods:
Abstract: Owners and operators of SUMMARY: There will be a 2-day meeting • Federal eRulemaking Portal: http://
affected facilities are required to comply of the Federal Insecticide, Fungicide, www.regulations.gov. Follow the online
with reporting and recordkeeping and Rodenticide Act Scientific Advisory instructions for submitting comments.
requirements for the general provisions Panel (FIFRA SAP) to consider and Do not submit electronically any
of 40 CFR part 60, subpart A, as well as review a set of scientific issues being information you consider to be
for the specific requirements at 40 CFR considered by the Environmental Confidential Business Information (CBI)
part 60 subpart FFF. This includes Protection Agency regarding the human
mstockstill on DSK3G9T082PROD with NOTICES
or other information whose disclosure is
submitting initial notification reports, health and ecological risk assessments restricted by statute.
performance tests and periodic reports for SmartStax PRO (MON 89034 x • Mail: OPP Docket, Environmental
and results, and maintaining records of TC1507 x MON 87411 x DAS–59122–7), Protection Agency Docket Center (EPA/
the occurrence and duration of any a plant-incorporated protectant DC), (28221T), 1200 Pennsylvania Ave.
startup, shutdown, or malfunction in intended to control corn rootworm NW., Washington, DC 20460–0001.
the operation of an affected facility, or through ribonucleic acid (RNA) • Hand Delivery: To make special
any period during which the monitoring interference. arrangements for hand delivery or
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![42708 Federal Register / Vol. 81, No. 126 / Thursday, June 30, 2016 / Notices
the documents under consideration anticipated receiving pesticide C. FIFRA SAP Documents and Meeting
(including previous scientific peer applications based on RNAi Minutes
review) before the candidate is technologies and identified the need to EPA’s background paper, related
considered further for service on the better understand the scientific issues supporting materials, charge/questions
FIFRA SAP. Those who are selected concerning the assessment of the risks to FIFRA SAP, FIFRA SAP composition
from the pool of prospective candidates to human health and the environment (i.e., members and ad hoc members for
will be asked to attend the public that RNAi technologies pose, it this meeting), and the meeting agenda
meetings and to participate in the convened a January 28, 2014, Federal will be available by approximately late
discussion of key issues and Insecticide, Fungicide, and Rodenticide August. In addition, the Agency may
assumptions at these meetings. In Act Scientific Advisory Panel (FIFRA provide additional background
addition, they will be asked to review SAP). This FIFRA SAP provided EPA documents as the materials become
and to help finalize the meeting with scientific advice regarding the available. You may obtain electronic
minutes. The list of FIFRA SAP framework for assessing RNAi pesticide copies of these documents, and certain
members participating at this meeting products. other related documents that might be
will be posted on the FIFRA SAP Web On October 29, 2015, EPA registered available at http://www.regulations.gov
site at http://www.epa.gov/sap or may and the FIFRA SAP Web site at http://
MON 87411, a corn plant-incorporated
be obtained from the OPP Docket at www.epa.gov/sap.
protectant (PIP) for seed increase/
http://www.regulations.gov. FIFRA SAP will prepare meeting
breeding purposes only and not for
II. Background commercial release, with a time minutes summarizing its
limitation of 2 years and a per-season recommendations to the Agency
A. Purpose of FIFRA SAP approximately 90 days after the
acreage cap of 15,000 acres. In addition
FIFRA SAP serves as the primary to Bacillus thuringiensis (Bt) Cry3Bb1 meeting. The meeting minutes will be
scientific peer review mechanism of protein, MON 87411 expresses DvSnf7 posted to the FIFRA SAP Web site or
EPA’s Office of Chemical Safety and dsRNA. Upon consumption by corn may be obtained from the OPP Docket
Pollution Prevention and is structured rootworm (CRW), the insect’s RNAi at http://www.regulations.gov.
to provide scientific advice, information machinery recognizes DvSnf7 dsRNA, Authority: 7 U.S.C. 136 et seq.; 21 U.S.C.
and recommendations to the EPA resulting in down-regulation of the 301 et seq.
Administrator on pesticides and targeted DvSnf7 gene and leading to Dated: June 23, 2016.
pesticide-related issues as to the impact CRW mortality. Earlier this year, EPA Stanley Barone,
of regulatory actions on health and the received applications from Monsanto Acting Director, Office of Science
environment. FIFRA SAP is a federal Company and Dow AgroSciences, LLC, Coordination and Policy.
advisory committee established in 1975 requesting registration of commercial [FR Doc. 2016–15589 Filed 6–29–16; 8:45 am]
under FIFRA that operates in release RNAi PIPs expressing DvSnf7 BILLING CODE 6560–50–P
accordance with requirements of the dsRNA and known by the name
Federal Advisory Committee Act (5 SmartStax PRO. SmartStax PRO also
U.S.C. Appendix). FIFRA SAP is expresses several Bt insecticidal Cry FEDERAL COMMUNICATIONS
composed of a permanent panel proteins. COMMISSION
consisting of seven members who are
EPA will present the human health
appointed by the EPA Administrator Deletion of Items From Sunshine Act
risk assessment conducted for DvSnf7
from nominees provided by the National Meeting
dsRNA, as expressed in SmartStax PRO,
Institutes of Health and the National
and will consider the fate of ingested June 24, 2016.
Science Foundation. FIFRA established
dsRNA and the potential for impacts on The following items have been
a Science Review Board (SRB)
gene expression and the immune deleted from the list of items scheduled
consisting of at least 60 scientists who
system. The action of a RNA for consideration at the Friday, June 24,
are available to FIFRA SAP on an ad hoc
interference construct relies upon some 2016, Open Meeting and previously
basis to assist in reviews conducted by
level of sequence homology with the listed in the Commission’s Notice of
FIFRA SAP. As a scientific peer review
target gene transcript; however, the June 17, 2016. Items 1, 2, 4, 5, 6, and
mechanism, FIFRA SAP provides
fidelity of the sequence match may vary 7 on the consent agenda have been
comments, evaluations, and
in some instances. EPA will discuss the adopted by the Commission.
recommendations to improve the
role that bioinformatic analysis may
effectiveness and quality of analyses 2. Public Safety & Homeland Security
play in understanding and predicting
made by Agency scientists. Members of Bureau:
possible off-target effects within the host Title: Amendment of Part 11 of the
the FIFRA SAP are scientists who have
genome, as well as in predicting Commission’s Rules Regarding the
sufficient professional qualifications,
nontarget effects as part of the ecological Emergency Alert System (PS Docket
including training and experience, to
risk assessment. No. 15–94)
provide expert advice and
recommendations to the Agency. EPA will also present an ecological Summary: The Commission will
risk assessment for DvSnf7 dsRNA, as consider a Report and Order that
B. Public Meeting expressed in SmartStax PRO, and will would revise the Emergency Alert
The use of RNA interference (RNAi) include descriptions of environmental System rules by adding new event
gene silencing technology, particularly fate and nontarget exposure, data codes covering extreme high winds
mstockstill on DSK3G9T082PROD with NOTICES
RNAi for pesticidal purposes to control reviewed in support of the risk and storm surges caused by
macroorganism pests, is a relatively assessment, risk characterization and Category 3 (and greater) hurricanes.
recent innovation. Post-transcriptional description, and uncertainties. The * * * * *
silencing of gene function is a very charge to the panel will request expert
rapid process where double-stranded opinion on completeness of the data set Consent Agenda
RNA (dsRNA) directs sequence-specific and uncertainties related to the risk The Commission will consider the
degradation of a RNA. As EPA conclusions. following subjects listed below as a
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Document Created: 2018-02-08 07:45:36
Document Modified: 2018-02-08 07:45:36
| Category | Regulatory Information | |
| Collection | Federal Register | |
| sudoc Class | AE 2.7: GS 4.107: AE 2.106: | |
| Publisher | Office of the Federal Register, National Archives and Records Administration | |
| Section | Notices | |
| Action | Notice. | |
| Dates | The meeting will be held on September 27-28, 2016, from approximately 9:00 a.m. to 5:00 p.m. | |
| Contact | Steven Knott, DFO, Office of Science Coordination and Policy (7201M), Environmental Protection Agency, 1200 Pennsylvania Ave. NW., Washington, DC 20460-0001; telephone number: | |
| FR Citation | 81 FR 42706 |
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