81 FR 48438 - Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Notice of Closed Meeting

DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health

Federal Register Volume 81, Issue 142 (July 25, 2016)

Page Range		48438-48439
FR Document		2016-17423

Federal Register, Volume 81 Issue 142 (Monday, July 25, 2016)

[Federal Register Volume 81, Number 142 (Monday, July 25, 2016)]
[Notices]
[Pages 48438-48439]
From the Federal Register Online  [www.thefederalregister.org]
[FR Doc No: 2016-17423]


-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Eunice Kennedy Shriver National Institute of Child Health and 
Human Development (NICHD); Notice of Closed Meeting

    Pursuant to section 10(d) of the Federal Advisory Committee Act, as 
amended (5 U.S.C. App.), notice is hereby given of the following 
meeting.
    The meeting will be closed to the public in accordance with the 
provisions set forth in section 552b(c)(4) and 552b(c)(6), Title 5 
U.S.C., as amended. The grant applications and the discussions could 
disclose confidential trade secrets or commercial property such as 
patentable material, and personal information concerning individuals 
associated with the grant applications, the disclosure of which would 
constitute a clearly unwarranted invasion of personal privacy.

    Name of Committee: National Advisory Child Health and Human 
Development Council.
    Date: August 22, 2016.
    Time: 2:00 p.m. to Adjournment.
    Agenda: To review and evaluate grant applications.
    Place: National Institutes of Health, 6710B Rockledge Drive, 
Bethesda, MD 20892 (Telephone Conference Call).
    Contact Person: Della Hann, Ph.D., Director, Division of 
Extramural Research, Eunice Kennedy Shriver National Institute of

[[Page 48439]]

Child Health and Human Development, NIH, 6710B Rockledge Drive, Room 
2314, Bethesda, MD 20892, (301) 496-8535, [email protected].

(Catalogue of Federal Domestic Assistance Program Nos. 93.864, 
Population Research; 93.865, Research for Mothers and Children; 
93.929, Center for Medical Rehabilitation Research; 93.209, 
Contraception and Infertility Loan Repayment Program, National 
Institutes of Health, HHS)

    Dated: July 19, 2016.
Michelle Trout,
Program Analyst, Office of Federal Advisory Committee Policy.

[FR Doc. 2016-17423 Filed 7-22-16; 8:45 am]
 BILLING CODE 4140-01-P

48438 Federal Register / Vol. 81, No. 142 / Monday, July 25, 2016 / Notices

care environments. Non-chemical this project is to provide valuable data methods and practices for preventing
stressors, such as noise, number of about the levels of lead, allergens, and controlling indoor environmental
windows in the child care center, tree pesticides, and PCBs in child care hazards. This project may be replicated
cover, and shade cover in play area, will facilities located in Portland Area in other IHS areas.
be included in data collection. Indian Country. This project will help Agency Form Numbers: None.
Community factors, such as mapping prioritize services and funding based on
Members of Affected Public:
the locations of the child care facilities, known needs and risks in order to help
Operators of tribal child care facilities
roads, and agricultural operations, will facilities obtain needed services. This
and pesticide applicators who work in
be included in data collection in order data may help tribes secure funding
child care facilities.
to evaluate the relationship between from the federal Head Start program and
indoor air quality and the outdoor other funding sources for repairs, Status of the Proposed Information
environment. rehabilitations or other corrective Collection: New request.
IHS and EPA will also incorporate action. This study may also provide The table below provides: Types of
follow-up outreach and education with federal Head Start and Tribal Programs data collection instruments, Estimated
facilities to explain results and suggest with data to improve standards and number of respondents, Number of
corrective actions to remediate or initiate policy changes, if necessary. IHS responses per respondent, Annual
reduce exposures from lead, allergens, will also provide indoor air quality kits number of responses, Average burden
pesticides, and PCBs that are detected in to the facilities and environmental hour per response, and Total annual
the facilities. The principal purpose of health training to center staff to provide burden hours.

Average
Number
Number of burden per Estimated
Data collection instrument Type of respondent responses per
respondents response burden hours
respondent (hours)

Child Care Center Director Questionnaire ...... Child Care Center Director 45 1 1.5 67.5
Pesticide Applicator Questionnaire ................. Pesticide Applicator ........... 30 1 0.5 15

Total .......................................................... ............................................ 75 ........................ ........................ 82.5

There are no direct costs to and personal information concerning DEPARTMENT OF HEALTH AND
respondents other than their time to individuals associated with the grant HUMAN SERVICES
voluntarily complete the forms and applications, the disclosure of which
submit them for consideration. would constitute a clearly unwarranted National Institutes of Health
Comment Due Date: Comments invasion of personal privacy.
regarding this information collection are Eunice Kennedy Shriver National
best assured of having full effect if Name of Committee: Eunice Kennedy Institute of Child Health and Human
received within 60 days of the date of Shriver, National Institute of Child Health Development (NICHD); Notice of
this publication. and Human Development Special Emphasis Closed Meeting
Panel; Genetic Quality Control in the
Dated: July 13, 2016. Mammalian Germline. Pursuant to section 10(d) of the
Elizabeth A. Fowler, Date: September 6, 2016. Federal Advisory Committee Act, as
Deputy Director for Management Operations, Time: 12:00 p.m. to 3:00 p.m. amended (5 U.S.C. App.), notice is
Indian Health Service. Agenda: To review and evaluate grant hereby given of the following meeting.
[FR Doc. 2016–17494 Filed 7–22–16; 8:45 am] applications. The meeting will be closed to the
BILLING CODE 4165–16–P Place: National Institutes of Health, 6710B public in accordance with the
Rockledge Drive, Room 2137C, Bethesda, MD provisions set forth in section 552b(c)(4)
20892 (Telephone Conference Call). and 552b(c)(6), Title 5 U.S.C., as
DEPARTMENT OF HEALTH AND Contact Person: Dennis E. Leszczynski, amended. The grant applications and
HUMAN SERVICES Ph.D., Scientific Review Officer, Division of the discussions could disclose
Scientific Review, Eunice Kennedy Shriver confidential trade secrets or commercial
National Institutes of Health National Institute of Child Health and property such as patentable material,
Human Development, NIH, 6710B Rockledge and personal information concerning
Eunice Kennedy Shriver National Drive, Room 2137C, Bethesda, MD 20892, individuals associated with the grant
Institute of Child Health & Human (301) 435–6884, leszczyd@mail.nih.gov. applications, the disclosure of which
Development; Notice of Closed
(Catalogue of Federal Domestic Assistance would constitute a clearly unwarranted
Meeting
Program Nos. 93.864, Population Research; invasion of personal privacy.
Pursuant to section 10(d) of the 93.865, Research for Mothers and Children; Name of Committee: National Advisory
Federal Advisory Committee Act, as 93.929, Center for Medical Rehabilitation Child Health and Human Development
amended (5 U.S.C. App.), notice is Research; 93.209, Contraception and Council.
hereby given of the following meeting. Infertility Loan Repayment Program, National Date: August 22, 2016.
The meeting will be closed to the Institutes of Health, HHS) Time: 2:00 p.m. to Adjournment.
mstockstill on DSK3G9T082PROD with NOTICES

public in accordance with the Agenda: To review and evaluate grant
Dated: July 19, 2016. applications.
provisions set forth in sections Michelle Trout, Place: National Institutes of Health, 6710B
552b(c)(4) and 552b(c)(6), Title 5 U.S.C., Rockledge Drive, Bethesda, MD 20892
Program Analyst, Office of Federal Advisory
as amended. The contract proposals and (Telephone Conference Call).
Committee Policy.
the discussions could disclose Contact Person: Della Hann, Ph.D.,
[FR Doc. 2016–17422 Filed 7–22–16; 8:45 am]
confidential trade secrets or commercial Director, Division of Extramural Research,
property such as patentable material, BILLING CODE 4140–01–P Eunice Kennedy Shriver National Institute of

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Federal Register / Vol. 81, No. 142 / Monday, July 25, 2016 / Notices 48439

Child Health and Human Development, NIH, cell lines, and orthotopic models based Intellectual Property: Research use—
6710B Rockledge Drive, Room 2314, on Rb, p53 and/or Brca 1/2 inactivation no patent protection will be sought.
Bethesda, MD 20892, (301) 496–8535, useful for biomarker discovery and Publications:
dhann@mail.nih.gov. preclinical testing. 1. Szabova L., Yin C., Bupp S., et al.
(Catalogue of Federal Domestic Assistance Description of Technology: The high Perturbation of Rb, p53 and Brca1
Program Nos. 93.864, Population Research; mortality rate from ovarian cancers can or Brca2 cooperate in inducing
93.865, Research for Mothers and Children;
be attributed to late-stage diagnosis and metastatic serous epithelial ovarian
93.929, Center for Medical Rehabilitation
Research; 93.209, Contraception and lack of effective treatment. Despite cancer. Cancer research.
Infertility Loan Repayment Program, National enormous effort to develop better 2012;72(16):4141–4153.
Institutes of Health, HHS) targeted therapies, platinum-based 2. Szabova L., Bupp S., Kamal M., et al.
Dated: July 19, 2016. chemotherapy still remains the standard Pathway-Specific Engineered
Michelle Trout, of care for ovarian cancer patients, and Mouse Allograft Models
resistance occurs at a high rate. One of Functionally Recapitulate Human
Program Analyst, Office of Federal Advisory
Committee Policy. the rate limiting factors for translation of Serous Epithelial Ovarian Cancer.
new drug discoveries into clinical Katoh M., ed. PLoS ONE.
[FR Doc. 2016–17423 Filed 7–22–16; 8:45 am] treatments has been the lack of suitable 2014;9(4):e95649.
BILLING CODE 4140–01–P preclinical cancer models with high Collaboration Opportunity:
predictive value. Researchers at the NCI seek licensing
NCI CAPR has developed Tri-allelic and/or co-development research
DEPARTMENT OF HEALTH AND K18–T121 tg/∂ /Brca1 fl/fl /p53 fl/fl SEOC
HUMAN SERVICES collaborations for the commercialization
GEM Model, GEM-derived SEOC of agents for the treatment of SEOC.
National Institutes of Health orthotopic mouse model, and biological Contact Information: Requests for
materials derived therefrom, with copies of the patent application or
Government-Owned Inventions; several key histopathologic, inquiries about licensing, research
Availability for Licensing immunophenotypical, and genetic collaborations, and co-development
features of human SEOC. SEOC GEMs opportunities should be sent to John D.
AGENCY: National Institutes of Health, were utilized to create orthotopic Hewes, Ph.D., email: john.hewes@
HHS. immunocompetent transplant models, nih.gov.
ACTION: Notice. and to generate synchronized cohorts of Dated: July 11, 2016.
mice suitable for preclinical studies.
SUMMARY: The invention listed below is John D. Hewes,
NCI CAPR conducted studies that
owned by an agency of the U.S. determine these models are tractable for Technology Transfer Specialist, Technology
Government and is available for Transfer Center, National Cancer Institute.
use in routine efficacy studies and
licensing and/or co-development in the demonstrate the utility of these models [FR Doc. 2016–17419 Filed 7–22–16; 8:45 am]
U.S. in accordance with 35 U.S.C. 209 in evaluating the potential efficacy of BILLING CODE 4140–01–P
and 37 CFR part 404 to achieve novel therapeutics for ovarian cancer.
expeditious commercialization of Potential Commercial Applications:
results of federally-funded research and DEPARTMENT OF HEALTH AND
• These models serve as a foundation
development. Foreign patent HUMAN SERVICES
for preclinical research and evaluation
applications are filed on selected of efficacy of novel therapeutics for
inventions to extend market coverage National Institutes of Health
ovarian cancer.
for companies and may also be available • The GEM models described here National Heart, Lung, and Blood
for licensing and/or co-development. can be used to develop cell lines and Institute; Notice of Closed Meeting
ADDRESSES: Invention Development and allograft models for evaluating drug
Marketing Unit, Technology Transfer potency relative to Brca1 mutation Pursuant to section 10(d) of the
Center, National Cancer Institute, 9609 status. Federal Advisory Committee Act, as
Medical Center Drive, Mail Stop 9702, • These mouse models provide the amended (5 U.S.C. App.), notice is
Rockville, MD, 20850–9702. opportunity for evaluation of effective hereby given of the following meeting.
FOR FURTHER INFORMATION CONTACT: therapeutics, including prediction of The meeting will be closed to the
Information on licensing and co- differential responses in Brca1-wild public in accordance with the
development research collaborations, type and Brca1–deficient tumors and provisions set forth in sections
and copies of the U.S. patent development of relevant biomarkers. 552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
applications listed below may be Value Proposition: as amended. The grant applications and
obtained by contacting: Attn. Invention • Novel resource for evaluating the discussions could disclose
Development and Marketing Unit, disease etiology and biomarkers, confidential trade secrets or commercial
Technology Transfer Center, National therapeutic evaluation, and improved property such as patentable material,
Cancer Institute, 9609 Medical Center imaging strategies in epithelial ovarian and personal information concerning
Drive, Mail Stop 9702, Rockville, MD cancer individuals associated with the grant
20850–9702, Tel. 240–276–5515 or • Similarity to human ovarian cancer applications, the disclosure of which
email ncitechtransfer@mail.nih.gov. A based on transcriptional profiling would constitute a clearly unwarranted
signed Confidential Disclosure • Suitable preclinical cancer models invasion of personal privacy.
mstockstill on DSK3G9T082PROD with NOTICES

Agreement may be required to receive with high predictive value. Name of Committee: National Heart, Lung,
copies of the patent applications. Development Stage: Pre-clinical (in and Blood Institute Special Emphasis Panel
Pediatric Heart Network Clinical Research
SUPPLEMENTARY INFORMATION: vivo validation).
Centers (UG1).
Technology description follows. Inventor(s): Simone Difilippantonio, Date: August 17–18, 2016
Title of invention: Novel metastatic Terry Van Dyke, Zoe Weaver Ohler, Time: 8:30 a.m. to 5:00 p.m.
serous epithelial ovarian cancer (SEOC) Ludmila Szabova, Sujata Bupp, Yurong Agenda: To review and evaluate grant
genetically engineered mouse models, Song, Chaoying Yin. applications.

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Document Created: 2016-07-23 02:00:22
Document Modified: 2016-07-23 02:00:22

Category		Regulatory Information
Collection		Federal Register
sudoc Class		AE 2.7: GS 4.107: AE 2.106:
Publisher		Office of the Federal Register, National Archives and Records Administration
Section		Notices
Dates		August 22, 2016.
FR Citation		81 FR 48438

81 FR 48438 - Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Notice of Closed Meeting

DEPARTMENT OF HEALTH AND HUMAN SERVICESNational Institutes of Health

Federal Register Volume 81, Issue 142 (July 25, 2016)

DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health