83_FR_58488 83 FR 58265 - Government-Owned Inventions; Availability for Licensing

83 FR 58265 - Government-Owned Inventions; Availability for Licensing

DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health

Federal Register Volume 83, Issue 223 (November 19, 2018)

Page Range58265-58265
FR Document2018-25194

The inventions listed below are owned by an agency of the U.S. Government and are available for licensing in the U.S. to achieve expeditious commercialization of results of federally-funded research and development.

Federal Register, Volume 83 Issue 223 (Monday, November 19, 2018)
[Federal Register Volume 83, Number 223 (Monday, November 19, 2018)]
[Notices]
[Page 58265]
From the Federal Register Online  [www.thefederalregister.org]
[FR Doc No: 2018-25194]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Government-Owned Inventions; Availability for Licensing

AGENCY: National Institutes of Health, HHS.

ACTION: Notice.

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SUMMARY: The inventions listed below are owned by an agency of the U.S. 
Government and are available for licensing in the U.S. to achieve 
expeditious commercialization of results of federally-funded research 
and development.

FOR FURTHER INFORMATION CONTACT: Licensing information may be obtained 
by emailing the indicated licensing contact at the National Heart, 
Lung, and Blood, Office of Technology Transfer and Development Office 
of Technology Transfer, 31 Center Drive, Room 4A29, MSC2479, Bethesda, 
MD 20892-2479; telephone: 301-402-5579. A signed Confidential 
Disclosure Agreement may be required to receive any unpublished 
information.

SUPPLEMENTARY INFORMATION: Technology description follows.

Sickle Cell Anemia Treatment Through RIOK3 Inhibition

    Available for licensing and commercial development are methods for 
the treatment of beta-globinapathies such as sickle cell disease and 
beta-thalassemia by inhibiting the expression and/or activity of RIOK3 
in erythroid cells such as primary erythroid progenitor cell or a CD34+ 
erythroid cells. RIOK3 inhibitors contemplated within the scope of the 
invention can be antibodies, siRNAs, microRNAs, antisense 
oligonucleotides or small molecules like Midostaurin, Axitinib, 
Bosutinib, or Ruxolitinib.

Potential Commercial Applications:

 Sickle cell disease
 beta thalassemia

Development Stage:

 Early stage
    Inventors: Bjorg Gudmundsdottir, Laxminath Tumburu, John Tisdale 
(all of NHLBI)
    Intellectual Property: HHS Reference No. E-200-2018; U.S 
Provisional Patent Application 62/756,497 filed November 6, 2018.
    Licensing Contact: Michael Shmilovich, Esq, CLP; 301-435-5019; 
[email protected].

    Dated: November 7, 2018.
Michael A. Shmilovich,
Senior Licensing and Patenting Manager, National Heart, Lung, and Blood 
Institute, Office of Technology Transfer and Development.
[FR Doc. 2018-25194 Filed 11-16-18; 8:45 am]
 BILLING CODE 4140-01-P



                                                                          Federal Register / Vol. 83, No. 223 / Monday, November 19, 2018 / Notices                                                 58265

                                               Podcasting website (http://                             Center Drive, Room 7W444, Bethesda, MD                SUPPLEMENTARY INFORMATION:
                                               videocast.nih.gov).                                     20892, 240–276–6340, grayp@mail.nih.gov.              Technology description follows.
                                                 A portion of the National Cancer                         Any interested person may file written
                                                                                                       comments with the committee by forwarding             Sickle Cell Anemia Treatment Through
                                               Advisory Board meeting will be closed
                                                                                                       the statement to the Contact Person listed on         RIOK3 Inhibition
                                               to the public in accordance with the
                                                                                                       this notice. The statement should include the           Available for licensing and
                                               provisions set forth in section                         name, address, telephone number and when
                                               552b(c)(6), Title 5 U.S.C., as amended,                                                                       commercial development are methods
                                                                                                       applicable, the business or professional
                                               for the review, discussion, and                         affiliation of the interested person.
                                                                                                                                                             for the treatment of beta-globinapathies
                                               evaluation of individual intramural                        In the interest of security, NIH has               such as sickle cell disease and beta-
                                               programs and projects conducted by the                  instituted stringent procedures for entrance          thalassemia by inhibiting the expression
                                               National Cancer Institute, including                    onto the NCI-Shady Grove campus. All                  and/or activity of RIOK3 in erythroid
                                               consideration of personnel                              visitors will be asked to show one form of            cells such as primary erythroid
                                               qualifications and performance, and the                 identification (for example, a government-            progenitor cell or a CD34+ erythroid
                                                                                                       issued photo ID, driver’s license, or passport)       cells. RIOK3 inhibitors contemplated
                                               competence of individual investigators,                 and to state the purpose of their visit.
                                               the disclosure of which would                                                                                 within the scope of the invention can be
                                                                                                          Information is also available on the
                                               constitute a clearly unwarranted                        Institute’s/Center’s home page: NCAB: http://
                                                                                                                                                             antibodies, siRNAs, microRNAs,
                                               invasion of personal privacy.                           deainfo.nci.nih.gov/advisory/ncab/ncab.htm,           antisense oligonucleotides or small
                                                                                                       BSA: http://deainfo.nci.nih.gov/advisory/             molecules like Midostaurin, Axitinib,
                                                 Name of Committee: National Cancer
                                               Advisory Board, Ad Hoc Subcommittee on                  bsa/bsa.htm, where an agenda and any                  Bosutinib, or Ruxolitinib.
                                               Global Cancer Research.                                 additional information for the meeting will
                                                                                                       be posted when available.
                                                                                                                                                             Potential Commercial Applications:
                                                 Open: December 3, 2018, 5:30 p.m. to 7:00
                                               p.m.                                                    (Catalogue of Federal Domestic Assistance             • Sickle cell disease
                                                 Agenda: Discussion on Global Cancer                   Program Nos. 93.392, Cancer Construction;             • beta thalassemia
                                               Research.                                               93.393, Cancer Cause and Prevention
                                                                                                       Research; 93.394, Cancer Detection and
                                                                                                                                                             Development Stage:
                                                 Place: Gaithersburg Marriott
                                               Washingtonian Center, 9751 Washington                   Diagnosis Research; 93.395, Cancer                    • Early stage
                                               Boulevard, Gaithersburg, MD 20878.                      Treatment Research; 93.396, Cancer Biology               Inventors: Bjorg Gudmundsdottir,
                                                 Contact Person: Dr. Robert T. Croyle,                 Research; 93.397, Cancer Centers Support;             Laxminath Tumburu, John Tisdale (all
                                               Acting Executive Secretary, NCAB Ad Hoc                 93.398, Cancer Research Manpower; 93.399,             of NHLBI)
                                               Subcommittee on Global Cancer Research,                 Cancer Control, National Institutes of Health,           Intellectual Property: HHS Reference
                                               National Cancer Institute—Shady Grove,                  HHS)                                                  No. E–200–2018; U.S Provisional Patent
                                               National Institutes of Health, 9609 Medical               Dated: November 14, 2018.                           Application 62/756,497 filed November
                                               Center Drive, Room 4E420, Bethesda, MD                  Natasha M. Copeland,                                  6, 2018.
                                               20892, (240) 276–6690, croyler@mail.nih.gov.                                                                     Licensing Contact: Michael
                                                                                                       Program Analyst, Office of Federal Advisory
                                                 Name of Committee: NCI Board of                       Committee Policy.                                     Shmilovich, Esq, CLP; 301–435–5019;
                                               Scientific Advisors and National Cancer                                                                       shmilovm@mail.nih.gov.
                                               Advisory Board.                                         [FR Doc. 2018–25193 Filed 11–16–18; 8:45 am]
                                                 Open: December 4, 2018, 8:45 a.m. to 4:15             BILLING CODE 4140–01–P                                  Dated: November 7, 2018.
                                               p.m.                                                                                                          Michael A. Shmilovich,
                                                 Agenda: Joint meeting of the NCI Board of                                                                   Senior Licensing and Patenting Manager,
                                               Scientific Advisors and National Cancer                 DEPARTMENT OF HEALTH AND                              National Heart, Lung, and Blood Institute,
                                               Advisory Board—NCI Director’s report,                   HUMAN SERVICES                                        Office of Technology Transfer and
                                               presentations, and review of concepts.                                                                        Development.
                                                 Closed: December 4, 2018, 4:15 p.m. to                National Institutes of Health                         [FR Doc. 2018–25194 Filed 11–16–18; 8:45 am]
                                               5:15 p.m.
                                                                                                                                                             BILLING CODE 4140–01–P
                                                 Agenda: Review of intramural program site             Government-Owned Inventions;
                                               visit outcomes and the discussion of                    Availability for Licensing
                                               confidential personnel issues.
                                                 Place: National Cancer Institute—Shady                AGENCY:    National Institutes of Health,             DEPARTMENT OF HEALTH AND
                                               Grove, 9609 Medical Center Drive, Room                  HHS.                                                  HUMAN SERVICES
                                               TE406 & 408, Rockville, MD 20850.                       ACTION:   Notice.
                                                 Contact Person: Paulette S. Gray, Ph.D.,                                                                    National Institutes of Health
                                               Director, Division of Extramural Activities,            SUMMARY:    The inventions listed below
                                               National Cancer Institute—Shady Grove,                  are owned by an agency of the U.S.                    National Institute of Allergy and
                                               National Institutes of Health, 9609 Medical             Government and are available for                      Infectious Diseases; Notice of Closed
                                               Center Drive, Room 7W444, Bethesda, MD                  licensing in the U.S. to achieve                      Meeting
                                               20892, 240–276–6340, grayp@mail.nih.gov.
                                                                                                       expeditious commercialization of                        Pursuant to section 10(d) of the
                                                 Name of Committee: NCI Board of                       results of federally-funded research and
                                               Scientific Advisors and National Cancer                                                                       Federal Advisory Committee Act, as
                                               Advisory Board.
                                                                                                       development.                                          amended, notice is hereby given of a
                                                 Open: December 5, 2018, 9:00 a.m. to 12:45            FOR FURTHER INFORMATION CONTACT:                      meeting of the Division of Intramural
                                               p.m.                                                    Licensing information may be obtained                 Research Board of Scientific Counselors.
                                                 Agenda: Joint meeting of the NCI Board of             by emailing the indicated licensing                     The meeting will be closed to the
                                               Scientific Advisors and National Cancer                 contact at the National Heart, Lung, and              public in accordance with the
                                               Advisory Board—Presentations and review of              Blood, Office of Technology Transfer                  provisions set forth in section
khammond on DSK30JT082PROD with NOTICES




                                               concepts.                                               and Development Office of Technology                  552b(c)(6), Title 5 U.S.C., as amended
                                                 Place: National Cancer Institute—Shady                Transfer, 31 Center Drive, Room 4A29,                 for the review, discussion, and
                                               Grove, 9609 Medical Center Drive, Room
                                               TE406 & 408, Rockville, MD 20850.
                                                                                                       MSC2479, Bethesda, MD 20892–2479;                     evaluation of individual intramural
                                                 Contact Person: Paulette S. Gray, Ph.D.,              telephone: 301–402–5579. A signed                     programs and projects conducted by the
                                               Director, Division of Extramural Activities,            Confidential Disclosure Agreement may                 NATIONAL INSTITUTE OF ALLERGY
                                               National Cancer Institute—Shady Grove,                  be required to receive any unpublished                AND INFECTIOUS DISEASES,
                                               National Institutes of Health, 9609 Medical             information.                                          including consideration of personnel


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Document Created: 2018-11-17 02:46:48
Document Modified: 2018-11-17 02:46:48
CategoryRegulatory Information
CollectionFederal Register
sudoc ClassAE 2.7:
GS 4.107:
AE 2.106:
PublisherOffice of the Federal Register, National Archives and Records Administration
SectionNotices
ActionNotice.
ContactLicensing information may be obtained by emailing the indicated licensing contact at the National Heart, Lung, and Blood, Office of Technology Transfer and Development Office of Technology Transfer, 31 Center Drive, Room 4A29, MSC2479, Bethesda, MD 20892-2479; telephone: 301-402-5579. A signed Confidential Disclosure Agreement may be required to receive any unpublished information.
FR Citation83 FR 58265 

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