SUPPLEMENTARY INFORMATION:

A prosperous bioeconomy provides a host of opportunities for the current and future growth of all sectors of the U.S. economy. Today, the Bioeconomy ecosystem in the United States is a rapidly changing technological and economic environment. Data rights, analysis, use, storage and security are all critical components of biotechnology, healthcare, medicine, public health, data science, energy, environment, and agriculture. Ongoing research and innovation in these areas provide the foundation for solving the problems of today and the potentially unforeseen issues of tomorrow. To that end, stimulating the research enterprise, developing and sustaining workforce talent, and supporting the infrastructure for the manufacturing of products remain critical components to any Bioeconomy objective.

To inform the Federal government's decision-making and establish the Nation's guiding values and principles in the promotion and protection of the U.S. Bioeconomy, OSTP seeks public input on how U.S. Government action regarding the Bioeconomy can support ( printed page 47562) scientific discovery, the development of technological advances, and increase the impact of a vibrant bioeconomy on the Nation's vitality and our citizens' lives. To that end, responders are specifically requested to answer one or more of the following questions in their submissions. Consortia responses are also encouraged.

1. What specific actions could the U.S. Government take to reinforce a values-based ecosystem that will guide the transformation and expansion of the U.S. Bioeconomy, in both the short- and long-term? Please consider:

a. Policy or regulatory opportunities and gaps throughout the continuum of basic science translation, product development and commercialization;

b. Scientific areas where research funding could be strategically targeted to stimulate discovery;

c. Novel public-private partnership mechanisms;

d. International opportunities;

e. Challenges to taking identified actions or implementing change.

2. In what ways can the U.S. Government partner with the private sector, industry, professional organizations, and academia to ensure the training and continued development of a skilled workforce to support the growth of the Bioeconomy? Please consider:

a. Potential needs and solutions at the skilled technical, undergraduate, professional master's program or graduate level;

b. Specific needs within basic science, translational research, product development, and commercialization;

c. Approaches for the development of non-traditional, multi-disciplinary educational backgrounds that address the convergent nature of emerging technologies and integrate core values including safety and security;

d. Effective geographic distribution of workforce and talent development across the United States;

e. The development of a public and private ecosystem that will attract and retain domestic and foreign talent within the United States at all skill levels.

3. In what ways can the U.S. Government partner with the private sector, industry, professional organizations, and academia to establish a more robust and efficient Bioeconomy infrastructure? Please consider:

a. Current infrastructure—from databases to world-class technology and manufacturing capabilities;

b. Geographic distribution of manufacturing capabilities compared to future manufacturing needs;

c. Leveraging existing public-private partnerships and identifying trusted information sharing mechanisms to accelerate innovation and facilitate fruitful, equitable domestic and international collaborations;

d. Institutional models for achieving translation of basic science discoveries to application and/or entry into the marketplace.

4. Across the spectrum, from basic discovery to practical application, what data policies, information-sharing mechanisms, and safeguards will be necessary for a prosperous U.S. Bioeconomy? Please consider:

a. Scientific, regulatory, manufacturing standards and/or benchmarks and/or best practices around data that should be developed to best accelerate Bioeconomy growth;

b. Possible safeguards for technology, data, and emergent products, such as patent/intellectual property protection, data quality and provenance validation, and privacy and security assurances.

84 FR 47561