Document

Schedules of Controlled Substances: Placement of O-Desmethyltramadol in Schedule I; Correction

On August 12, 2026, the Drug Enforcement Administration (DEA) published a temporary order placing O-desmethyltramadol (other names: O-DSMT; desmetramadol; 3-[(1R,2R)-2-[(dimethy...

Department of Justice
Drug Enforcement Administration
  1. 21 CFR Part 1308
  2. [Docket No. DEA-1641]

AGENCY:

Drug Enforcement Administration, Department of Justice.

ACTION:

Correcting amendment.

SUMMARY:

On August 12, 2026, the Drug Enforcement Administration (DEA) published a temporary order placing O -desmethyltramadol (other names: O -DSMT; desmetramadol; 3-[(1 R, 2 R)-2-[(dimethylamino)methyl]-1-hydroxycyclohexyl]phenol), including its salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers are possible, in schedule I of the Controlled Substances Act. DEA published this temporary order that specifically noted in the summary that the control of O -desmethyltramadol included its salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers are possible, however inadvertently omitted the correct language that should have been included. This document corrects that error, adding the correct language.

DATES:

This correcting amendment is effective October 9, 2026, until August 12, 2028, and applicable beginning August 12, 2026.

FOR FURTHER INFORMATION CONTACT:

Dr. Terrence L. Boos, Drug and Chemical Evaluation Section, Diversion Control Division, Drug Enforcement Administration; Telephone: (571) 362-3249.

SUPPLEMENTARY INFORMATION:

The placement of O -desmethyltramadol under schedule I was effective on August 12, 2026.[1] After publication of the temporary scheduling order, DEA inadvertently omitted the correct language that should have been included in 21 CFR part 1308. This document corrects the language in 21 CFR part 1308 to include the isomers, esters, ethers, salts, and salts of isomers, esters and ethers, whenever the existence of such isomers, esters, ethers and salts is possible of O -desmethyltramadol.

List of Subjects in 21 CFR Part 1308

  • Administrative practice and procedure
  • Drug traffic control
  • Reporting and recordkeeping requirements

For the reasons set out above, DEA corrects 21 CFR part 1308 with the following correcting amendment:

PART 1308—SCHEDULES OF CONTROLLED SUBSTANCES

1. The authority citation for part 1308 continues to read as follows:

Authority: 21 U.S.C. 811, 812, 871(b), 956(b), unless otherwise noted.

2. In § 1308.11, revise paragraph (h)(88) to read as follows:

Schedule I.
* * * * *

(h) * * *

 
*         *         *         *         *         *         *
(88) O -desmethyltramadol, its isomers, esters, ethers, salts, and salts of isomers, esters and ethers (other names: O -DSMT; desmetramadol; 3-[(1 R, 2 R)-2-[(dimethylamino)methyl]-1-hydroxycyclohexyl]phenol) 9667
 
*         *         *         *         *         *         *
( printed page 64618)

Signing Authority

This document of the Drug Enforcement Administration was signed on October 6, 2026, by DEA Administrator Terrance C. Cole. That document with the original signature and date is maintained by DEA. For administrative purposes only, and in compliance with requirements of the Office of the Federal Register, the undersigned DEA Federal Register Liaison Officer has been authorized to sign and submit the document in electronic format for publication, as an official document of DEA. This administrative process in no way alters the legal effect of this document upon publication in the Federal Register .

Heather Achbach,

Federal Register Liaison Officer, Drug Enforcement Administration.

Footnotes

1.  Schedules of Controlled Substances: Temporary Placement of O-desmethyltramadol in Schedule I, 91 FR 52013 (Aug. 12, 2026).

Back to Citation

[FR Doc. 2026-20748 Filed 10-8-26; 8:45 am]

BILLING CODE 4410-09-P

Legal Citation

Federal Register Citation

Use this for formal legal and research references to the published document.

91 FR 64617

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Use this when citing the archival web version of the document.

“Schedules of Controlled Substances: Placement of O-Desmethyltramadol in Schedule I; Correction,” thefederalregister.org (October 9, 2026), https://thefederalregister.org/documents/2026-20748/schedules-of-controlled-substances-placement-of-o-desmethyltramadol-in-schedule-i-correction.